KEGG   ORTHOLOGY: K18242
Entry
K18242                      KO                                     
Symbol
nagG
Name
salicylate 5-hydroxylase large subunit [EC:1.14.13.172]
Pathway
map00626  Naphthalene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00638  Salicylate degradation, salicylate => gentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00626 Naphthalene degradation
    K18242  nagG; salicylate 5-hydroxylase large subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.172  salicylate 5-hydroxylase
     K18242  nagG; salicylate 5-hydroxylase large subunit
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18242
Other DBs
RN: R07709 R07710
COG: COG4638
Genes
EBT: EBL_c34270
KAS: KATP_22590
PLU: plu1000
PLUM: A4R40_04995
PTT: VY86_00155
ALT: ambt_18005
TTU: TERTU_1474
MMW: Mmwyl1_2669
MME: Marme_2404
MPC: Mar181_2357
RSO: RSc1090(nagG)
RSE: F504_1061(ohbB)
REH: H16_A1633(nagG)
CNC: CNE_1c16410(nagG)
BMK: DM80_1440
BUB: BW23_5815
BGU: KS03_3913
BFN: OI25_3046
PPNO: DA70_21370
PPNM: LV28_08950
PPUL: RO07_03180
PSPU: NA29_24090
PAPI: SG18_03370
BPT: Bpet2804
AXX: ERS451415_00957(andAc_1)
POL: Bpro_0983
PNA: Pnap_2488
AAV: Aave_0165
AJS: Ajs_3090
AAA: Acav_0196
RTA: Rta_25990
LIM: L103DPR2_01958(nagG_2)
LIH: L63ED372_02715(nagG_2)
HYB: Q5W_19155
HPSE: HPF_02890(nagG)
LCH: Lcho_0797
AZO: azo2516(nagG)
AOA: dqs_2673
SWI: Swit_3056
SPHD: HY78_10295
BLAS: BSY18_3955
TMO: TMO_a0554(bphA)
ACTI: UA75_12800
ACAD: UA74_12720
AHG: AHOG_11995(nagG)
AG: AAD12607(nagG)
 » show all
Reference
PMID:9573207
  Authors
Fuenmayor SL, Wild M, Boyes AL, Williams PA
  Title
A gene cluster encoding steps in conversion of naphthalene to gentisate in Pseudomonas sp. strain U2.
  Journal
J Bacteriol 180:2522-30 (1998)
DOI:10.1128/JB.180.9.2522-2530.1998
  Sequence

KEGG   ORTHOLOGY: K18243
Entry
K18243                      KO                                     
Symbol
nagH
Name
salicylate 5-hydroxylase small subunit [EC:1.14.13.172]
Pathway
map00626  Naphthalene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00638  Salicylate degradation, salicylate => gentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00626 Naphthalene degradation
    K18243  nagH; salicylate 5-hydroxylase small subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.172  salicylate 5-hydroxylase
     K18243  nagH; salicylate 5-hydroxylase small subunit
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18243
Other DBs
RN: R07709 R07710
COG: COG5517
Genes
EBT: EBL_c34280
KAS: KATP_22600
PLU: plu1001
PLUM: A4R40_05000
PTT: VY86_00150
ALT: ambt_18010
TTU: TERTU_1475
CYQ: Q91_0876 Q91_2234
CZA: CYCME_2552
CYY: CPC19_01630
RSO: RSc1089(nagH)
RSN: RSPO_c02275(nagH)
RSE: F504_1060(ohbA)
REH: H16_A1632(nagH)
CNC: CNE_1c16400(nagH)
RME: Rmet_3712(nagH)
BMK: DM80_1441
BUB: BW23_5816
BGU: KS03_3914
BFN: OI25_3047
PPNO: DA70_21375
PPNM: LV28_08945
PPUL: RO07_03175
PSPU: NA29_24085
PAPI: SG18_03365
BPT: Bpet2805
AXX: ERS451415_00956(andAd_1)
POL: Bpro_0984
AAV: Aave_0166
AAA: Acav_0197
RTA: Rta_25980
LIM: L103DPR2_01957(nagH)
LIH: L63ED372_02714(nagH)
HYB: Q5W_19150
HPSE: HPF_02895(nagH)
LCH: Lcho_0796
AZO: azo2515(nagH)
AOA: dqs_2672
NAR: Saro_3834
BLAS: BSY18_3956
TMO: TMO_a0553
NFR: ERS450000_00310(andAd)
AG: AAD12608(nagH)
 » show all
Reference
PMID:9573207
  Authors
Fuenmayor SL, Wild M, Boyes AL, Williams PA
  Title
A gene cluster encoding steps in conversion of naphthalene to gentisate in Pseudomonas sp. strain U2.
  Journal
J Bacteriol 180:2522-30 (1998)
DOI:10.1128/JB.180.9.2522-2530.1998
  Sequence

KEGG   ORTHOLOGY: K14578
Entry
K14578                      KO                                     
Symbol
nahAb, nagAb, ndoA, nbzAb, dntAb
Name
naphthalene 1,2-dioxygenase ferredoxin component
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map00626  Naphthalene degradation
map00627  Aminobenzoate degradation
map00633  Nitrotoluene degradation
map00642  Ethylbenzene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00534  Naphthalene degradation, naphthalene => salicylate
M00638  Salicylate degradation, salicylate => gentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K14578  nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
   00633 Nitrotoluene degradation
    K14578  nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
   00642 Ethylbenzene degradation
    K14578  nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
   00626 Naphthalene degradation
    K14578  nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
   00624 Polycyclic aromatic hydrocarbon degradation
    K14578  nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K14578
Other DBs
RN: R02968 R05422 R05423 R05424 R05425 R05426 R05427 R06909 R06930 R06937 R07704 R07706 R07709 R07710 R09159 R09233
COG: COG2146
Genes
EBT: EBL_c34290(ndoA)
KAS: KATP_22610
PSD: DSC_14870
PPT: PPS_2607
PPI: ND054(nahAb)
PPUD: DW66_2865
PPJ: RK21_02167
PFK: PFAS1_28605
PMAO: PMYSY11_1632
PTAE: NCTC10697_01911(nahAb)
RMA: Rmag_0678
VOK: COSY_0630
IFO: CVFO_0997
APHF: CVPH_0811
PSE: NH8B_2003
RSO: RSc1088(nagAb)
RSL: RPSI07_2303(doxA)
RSM: CMR15_20207(doxA)
RSE: F504_1059
REH: H16_A1631(nagI)
BMK: DM80_1442(ndoA)
BUB: BW23_5817(ndoA)
BGU: KS03_3915(ndoA)
BXE: Bxe_C0940
BXB: DR64_7510(ndoA) DR64_8472
BFN: OI25_3048(ndoA)
PDIO: PDMSB3_0226(doxA)
PPNO: DA70_21380
PPNM: LV28_08940
PPUL: RO07_03170
PSPU: NA29_24080
PAPI: SG18_03360
BPAR: BN117_1348(ndoA)
BPA: BPP2189(ndoA)
BBH: BN112_1870(ndoA)
BBR: BB1586(ndoA)
BBM: BN115_1540(ndoA)
BBX: BBS798_1545(ndoA)
BPT: Bpet2806
AXX: ERS451415_00955(ndoA_1) ERS451415_02890(ndoA_2)
POL: Bpro_0985
AAV: Aave_0167
AJS: Ajs_3091
AAA: Acav_0198
CTES: O987_21885
LIM: L103DPR2_01956(ndoA)
LIH: L63ED372_02713(ndoA)
HYB: Q5W_18510
HPSE: HPF_02900(nagAb)
LCH: Lcho_0795
APET: ToN1_03800
AZO: azo2514(nagAb)
AOA: dqs_2671
AZA: AZKH_1938
BEL: BE61_33690(hcaC)
MIND: mvi_47130
MSL: Msil_1467
JAN: Jann_3956
SHUM: STHU_47060
TMO: TMO_a0552(doxA)
AG: AAA25905(nahAb) AAB09765(dntAb) AAL76201(nbzAb) AGH09225(mntAb)
 » show all
Reference
PMID:8486285
  Authors
Simon MJ, Osslund TD, Saunders R, Ensley BD, Suggs S, Harcourt A, Suen WC, Cruden DL, Gibson DT, Zylstra GJ
  Title
Sequences of genes encoding naphthalene dioxygenase in Pseudomonas putida strains G7 and NCIB 9816-4.
  Journal
Gene 127:31-7 (1993)
DOI:10.1016/0378-1119(93)90613-8
Reference
  Authors
Dennis JJ, Zylstra GJ
  Title
Complete sequence and genetic organization of pDTG1, the 83 kilobase naphthalene degradation plasmid from Pseudomonas putida strain NCIB 9816-4.
  Journal
J Mol Biol 341:753-68 (2004)
DOI:10.1016/j.jmb.2004.06.034
  Sequence

KEGG   ORTHOLOGY: K14581
Entry
K14581                      KO                                     
Symbol
nahAa, nagAa, ndoR, nbzAa, dntAa
Name
naphthalene 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.7]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map00626  Naphthalene degradation
map00627  Aminobenzoate degradation
map00633  Nitrotoluene degradation
map00642  Ethylbenzene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00534  Naphthalene degradation, naphthalene => salicylate
M00638  Salicylate degradation, salicylate => gentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
   00633 Nitrotoluene degradation
    K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
   00642 Ethylbenzene degradation
    K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
   00626 Naphthalene degradation
    K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
   00624 Polycyclic aromatic hydrocarbon degradation
    K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.7  ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific)
     K14581  nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K14581
Other DBs
RN: R02968 R05422 R05423 R05424 R05425 R05426 R05427 R06909 R06930 R06937 R07704 R07706 R07709 R07710 R09159 R09233
Genes
EBT: EBL_c34260(ndoR)
KAS: KATP_22580
PPI: ND053(nahAa)
PFK: PFAS1_28600
PSC: A458_06735
PSTU: UIB01_22615
PBM: CL52_14600
ALT: ambt_18035
MMW: Mmwyl1_2668
MME: Marme_2403
RSO: RSc1091(nagAa)
RSL: RPSI07_2300(ndoR)
RSM: CMR15_20210(ndoR)
RSE: F504_1062
BMK: DM80_1434(ndoR) DM80_1439(ndoR)
BFN: OI25_3043(ndoR)
PPNO: DA70_21365
PPNM: LV28_08955
PPUL: RO07_03185
PSPU: NA29_24095
PAPI: SG18_03375
AFQ: AFA_02200
POL: Bpro_0980
PNA: Pnap_2489
AAV: Aave_0164
AJS: Ajs_3089
AAA: Acav_0195
LCH: Lcho_0800
TIN: Tint_1781
THI: THI_2205
AZO: azo2517(nagAa)
AOA: dqs_2674
SHZ: shn_02370
MNO: Mnod_0136
RBM: TEF_01260
PSF: PSE_0864
LABT: FIU93_04780(nagAa1)
SGI: SGRAN_2805(thnY)
TMO: TMO_2240(ndoR)
AG: AAA25904(nahAa) AAB09763(dntAa) AAD12606(nagAa) AAL76199(nbzAa) AGH09224(mntAa)
 » show all
Reference
PMID:8486285
  Authors
Simon MJ, Osslund TD, Saunders R, Ensley BD, Suggs S, Harcourt A, Suen WC, Cruden DL, Gibson DT, Zylstra GJ
  Title
Sequences of genes encoding naphthalene dioxygenase in Pseudomonas putida strains G7 and NCIB 9816-4.
  Journal
Gene 127:31-7 (1993)
DOI:10.1016/0378-1119(93)90613-8
Reference
  Authors
Dennis JJ, Zylstra GJ
  Title
Complete sequence and genetic organization of pDTG1, the 83 kilobase naphthalene degradation plasmid from Pseudomonas putida strain NCIB 9816-4.
  Journal
J Mol Biol 341:753-68 (2004)
DOI:10.1016/j.jmb.2004.06.034
  Sequence

KEGG   ENZYME: 1.14.13.172
Entry
EC 1.14.13.172              Enzyme                                 
Name
salicylate 5-hydroxylase;
nagG (gene name);
nagH (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
salicylate,NADH:oxygen oxidoreductase (5-hydroxylating)
Reaction(IUBMB)
salicylate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O [RN:R07709]
Reaction(KEGG)
R07709;
(other) R07710
Substrate
salicylate [CPD:C00805];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
2,5-dihydroxybenzoate [CPD:C00628];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
This enzyme, which was characterized from the bacterium Ralstonia sp. U2, comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.7, ferredoxin---NAD(P)+ reductase), an iron-sulfur oxygenase, and ferredoxin.
History
EC 1.14.13.172 created 2013
Pathway
ec00626  Naphthalene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18242  salicylate 5-hydroxylase large subunit
K18243  salicylate 5-hydroxylase small subunit
Genes
EBTEBL_c34270 EBL_c34280
KASKATP_22590 KATP_22600
PLUplu1000 plu1001
PLUMA4R40_04995 A4R40_05000
PTTVY86_00150 VY86_00155
ALTambt_18005 ambt_18010
TTUTERTU_1474 TERTU_1475
CYQQ91_0876 Q91_2234
CZACYCME_2552
CYYCPC19_01630
MMWMmwyl1_2669 Mmwyl1_2670
MMEMarme_2404 Marme_2405
MPCMar181_2357 Mar181_2358
MPRIMP3633_2253 MP3633_2254
MARLHH196_06880 HH196_06885
FCEJN531_005580 JN531_005585
GBIPG2T_03615
RSORSc1089(nagH) RSc1090(nagG)
RSLRPSI07_2301 RPSI07_2302
RSNRSPO_c02274 RSPO_c02275(nagH)
RSMCMR15_20208 CMR15_20209
RSEF504_1060(ohbA) F504_1061(ohbB)
RSYRSUY_15110 RSUY_15120
RPJN234_28705 N234_28710
RMNTK49_07930 TK49_07935
RPUCDC45_05590 CDC45_05595
RSGJK151_19135 JK151_19140
REHH16_A1632(nagH) H16_A1633(nagG)
CNCCNE_1c16400(nagH) CNE_1c16410(nagG)
CUHBJN34_29220 BJN34_29225
REUReut_B4719 Reut_B4720
RMERmet_3712(nagH)
CBWRR42_s2751 RR42_s2752
CCUPBKK81_31195 BKK81_31200
CUPBKK80_25150 BKK80_25155
CUUBKK79_30860 BKK79_30865
COXE0W60_10140 E0W60_10145
BMKDM80_1440 DM80_1441
BCEPAPZ15_32865 APZ15_32870
BPYRABD05_24780 ABD05_24785
BUBBW23_5815 BW23_5816
BGLbglu_2g20110 bglu_2g20120
BGUKS03_3913 KS03_3914
BUGBC1001_0576 BC1001_0577
BUQAC233_10900 AC233_10905
BURKDM992_22160 DM992_22165
BPXBUPH_04466 BUPH_04467
BUZAYM40_33040 AYM40_33045 AYM40_33150 AYM40_33155
BFNOI25_3046 OI25_3047
PARBCJU94_38670 CJU94_38675
PTERC2L65_39070 C2L65_39075
PMEGFNZ07_23540 FNZ07_23545 FNZ07_29070 FNZ07_29075
PPKU875_04295 U875_04300
PPNODA70_21370 DA70_21375
PPNMLV28_08945 LV28_08950
PRBX636_05145 X636_05150
PPULRO07_03175 RO07_03180
PSPUNA29_24085 NA29_24090
PAPISG18_03365 SG18_03370
PVEUC34_19330 UC34_19335
POXMB84_24085 MB84_24090
PFGAB870_06325 AB870_06330
PNRAT302_02760 AT302_02765
PANDDRB87_17855 DRB87_17860
PFIBPI93_008710 PI93_008715
PCOMNTU39_21090 NTU39_21095
BPTBpet2804 Bpet2805
AXYAXYL_00938 AXYL_00939 AXYL_06578 AXYL_06581(bphA)
AXONH44784_011911 NH44784_011921
AXNAX27061_0965 AX27061_0966
AXXERS451415_00956(andAd_1) ERS451415_00957(andAc_1)
ADTAPT56_05010 APT56_05015
AISBUW96_21015 BUW96_21020
ASWCVS48_01680 CVS48_01685
ACHRC2U31_09370
ACHBDVB37_04180 DVB37_04185
ADYHLG70_17185 HLG70_17190
PUDG9Q38_01795 G9Q38_01800 G9Q38_05245 G9Q38_05250
PIGEGT29_23975 EGT29_23980
PARKLSG25_18560 LSG25_18565
RHFEUB48_13715 EUB48_13720
POLBpro_0983 Bpro_0984
PNAPnap_2462 Pnap_2487 Pnap_2488
POSDT070_14060 DT070_14065
POOF7R28_16540 F7R28_16545
AAVAave_0165 Aave_0166
AJSAjs_3090
AAAAcav_0196 Acav_0197
ACKC380_09995 C380_10000
VAPVapar_5348 Vapar_5349
VPEVarpa_2933 Varpa_2934
VPDVAPA_1c07030 VAPA_1c07040 VAPA_1c20400 VAPA_1c20410
VBOCKY39_17840 CKY39_17845
VAMC4F17_05690 C4F17_05695
RTARta_25980 Rta_25990
RTEAHK414_18880 HK414_18885
LIML103DPR2_01957(nagH) L103DPR2_01958(nagG_2)
LIHL63ED372_02714(nagH) L63ED372_02715(nagG_2)
HYRBSY239_1027 BSY239_1029
HYBQ5W_19150 Q5W_19155
HYLLPB072_20440 LPB072_20445
HPSEHPF_02890(nagG) HPF_02895(nagH)
HYNF9K07_14335 F9K07_14340
HTNKI616_03135 KI616_03140
ATERMW290_00170 MW290_00175
JAJEKL02_16425 EKL02_16430
MASWAM586_27630 AM586_27635 AM586_27695 AM586_27700 AM586_27790 AM586_27795
LCHLcho_0796 Lcho_0797
AZOazo2515(nagH) azo2516(nagG)
AOAdqs_2672 dqs_2673
AZRCJ010_15880 CJ010_15885
CFHC1707_18700 C1707_18705
BPONIFE19_06475 IFE19_06480
NARSaro_3834
NPPPP1Y_AT15862
SWISwit_0895 Swit_3056 Swit_3057
SPHDHY78_10290 HY78_10295 HY78_22215
SBARH5V43_22430
BLASBSY18_3955 BSY18_3956
PALGHFP57_01960 HFP57_01965
AZLAZL_a09200 AZL_a09210
ALIAZOLI_p20648 AZOLI_p20649
TMOTMO_a0553 TMO_a0554(bphA)
FERFNB15_08990 FNB15_08995
NFRERS450000_00310(andAd)
AGRAAGRA3207_001975
ACTIUA75_12800
ACADUA74_12720
AHGAHOG_11995(nagG)
HRSHER32_17540
CGLENCTC11432_01739
 » show all
Reference
1  [PMID:9573207]
  Authors
Fuenmayor SL, Wild M, Boyes AL, Williams PA
  Title
A gene cluster encoding steps in conversion of naphthalene to gentisate in Pseudomonas sp. strain U2.
  Journal
J Bacteriol 180:2522-30 (1998)
DOI:10.1128/JB.180.9.2522-2530.1998
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.172
IUBMB Enzyme Nomenclature: 1.14.13.172
ExPASy - ENZYME nomenclature database: 1.14.13.172
BRENDA, the Enzyme Database: 1.14.13.172

KEGG   REACTION: R07709
Entry
R07709                      Reaction                               
Name
salicylate,NADH:oxygen oxidoreductase (5-hydroxylating)
Definition
Salicylate + NADH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O
Equation
Comment
NADPH (see R07710)
Reaction class
RC00001  C00003_C00004
RC00490  C00628_C00805
Enzyme
Pathway
rn00626  Naphthalene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00638  Salicylate degradation, salicylate => gentisate
Orthology
K14578  naphthalene 1,2-dioxygenase ferredoxin component
K14581  naphthalene 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.7]
K18242  salicylate 5-hydroxylase large subunit [EC:1.14.13.172]
K18243  salicylate 5-hydroxylase small subunit [EC:1.14.13.172]
Other DBs
RHEA: 35310

KEGG   REACTION: R07710
Entry
R07710                      Reaction                               
Name
salicylate,NADPH:oxygen oxidoreductase (5-hydroxylating)
Definition
Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
Equation
Comment
NADH (see R07709)
Reaction class
RC00001  C00005_C00006
RC00490  C00628_C00805
Enzyme
Pathway
rn00626  Naphthalene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00638  Salicylate degradation, salicylate => gentisate
Orthology
K14578  naphthalene 1,2-dioxygenase ferredoxin component
K14581  naphthalene 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.7]
K18242  salicylate 5-hydroxylase large subunit [EC:1.14.13.172]
K18243  salicylate 5-hydroxylase small subunit [EC:1.14.13.172]

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