KEGG   ORTHOLOGY: K18285
Entry
K18285                      KO                                     
Symbol
mqnE
Name
aminodeoxyfutalosine synthase [EC:2.5.1.120]
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01240  Biosynthesis of cofactors
Module
M00930  Menaquinone biosynthesis, futalosine pathway
M00931  Menaquinone biosynthesis, modified futalosine pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K18285  mqnE; aminodeoxyfutalosine synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.120  aminodeoxyfutalosine synthase
     K18285  mqnE; aminodeoxyfutalosine synthase
Other DBs
RN: R10667
COG: COG1060
Genes
HPY: HP_0654
HEO: C694_03380
HPJ: jhp_0599
HPA: HPAG1_0639
HPS: HPSH_03585
HHP: HPSH112_03740
HHQ: HPSH169_03355
HHR: HPSH417_03165
HPG: HPG27_616
HPP: HPP12_0667
HPL: HPB8_857
HPZ: HPKB_0690
HPD: KHP_0667
HEY: MWE_0854
HPYR: K747_07365
HPYI: K750_05585
HPYU: K751_04110
HPYM: K749_02000
HEB: U063_0958
HEZ: U064_0962
HHE: HH_1021
HAC: Hac_0839
HMS: HMU06060
HCE: HCW_05760
HCM: HCD_05315
HCP: HCN_0074
HWI: A0Z60_03060(mqnE)
HSH: NHP194022_16570(mqnE)
WSU: WS2177
SUA: Saut_1516
SULN: FJR47_06880(mqnE)
SULG: FJR48_03675(mqnE)
SULC: CVO_02635(mqnE)
SPAL: FM071_07125(mqnE)
SSEI: FJR45_04310(mqnE)
SBAL: HUE88_02945(mqnE)
SMAS: HUE87_09410(mqnE)
SULR: B649_03315
CJE: Cj1368
CJU: C8J_1287
CJI: CJSA_1302
CJM: CJM1_1328
CJS: CJS3_1466
CJEJ: N564_01364
CJEU: N565_01404
CJEN: N755_01401
CJEI: N135_01456
CJER: H730_07805
CJY: QZ67_01505(mqnE_2)
CJQ: UC78_1315(mqnE_2)
CJR: CJE1560
CFZ: CSG_2310
CLA: CLA_0427
CCQ: N149_1332(mqnE)
CCF: YSQ_02015
CCY: YSS_07410
CCOI: YSU_02050
CCOF: VC76_06860(mqnE_2)
CCOO: ATE51_00826(mqnE_1)
CIS: CINS_0406
CVO: CVOL_0417
CPEL: CPEL_0436
CGRA: CGRAC_1021
CURE: CUREO_1051
CHYO: CHH_0511
CSPF: CSF_0597
CCUN: CCUN_1423
CLX: CLAN_0672
CAVI: CAV_1189
CHW: A2J15_004620(mqnE)
CAMY: CSUIS_0728
COJ: CORN_0434
CGEO: CGEO_1102
CCOR: CCORG_0672
CARM: CARM_0411
CMUC: CMCT_0624
CSHO: CSHOW_1378
CINF: CINF_0853
SDL: Sdel_1686
SMUL: SMUL_2362
SHAL: SHALO_2108
SULJ: SJPD1_2127
SULT: FA592_03180(mqnE)
ABU: Abu_0251
ABT: ABED_0234
ASK: EI285_08550(mqnE)
ATP: ATR_0180
ACIB: ACBT_1955
ACRE: ACRYA_1762
APOC: APORC_1850
ATHR: ATH_1745
AELL: AELL_0398
AAQI: AAQM_0315
ASUI: ASUIS_0323
ACLO: ACLO_0374
ARC: ABLL_0385
PACO: AACT_0429
ALK: ALEK_3080
AMYT: AMYT_2431
AMAR: AMRN_2478
ACAA: ACAN_2465
AMOL: AMOL_2449
APAI: APAC_2268
HBV: ABIV_2310
HEBR: AEBR_2684
HYO: NNO_1448
SUN: SUN_0538
SINU: IMZ28_08270(mqnE)
NIS: NIS_0648
NAM: NAMH_1275
CMED: FE773_03450(mqnE)
CPAF: C6V80_07275(mqnE)
GSU: GSU0441(mqnC-2)
GSK: KN400_0416(mqnC-2)
GME: Gmet_3391(mqnC-2)
GBZ: JZM60_06560(mqnE)
GEM: GM21_0218
GEB: GM18_0263
GEF: FO488_00965(mqnE)
GUR: Gura_4284
GEO: Geob_0418(mqnC-2)
GLO: Glov_0625
GBM: Gbem_0234(mqnC-2)
GBN: GEOBRER4_02290(mqnC-2)
GER: KP004_17930(mqnE)
GSUB: KP001_15300(mqnE)
GNT: KP003_21020(mqnE)
GPL: M1B72_20780(mqnE)
PCA: Pcar_0319(mqnC-2)
PPD: Ppro_3578
DES: DSOUD_0278(mqnC-2)
DEU: DBW_0510
DVE: DESUT3_01690(mqnC-2)
DEP: AOP6_0162(mqnC-2)
DVU: DVU_2756
DVL: Dvul_0551
DVM: DvMF_1188
DDS: Ddes_1279
DTR: RSDT_0540(mqnE)
DFL: DFE_3185
DMA: DMR_08720
DGG: DGI_2623
DDE: Dde_0798
DMS: E8L03_14105(mqnE)
DAS: Daes_2223
DPI: BN4_20498
PPRF: DPRO_3994(mqnE)
PSEL: GM415_11850(mqnE)
PSEF: PSDVSF_35170(mqnE)
PBIZ: LWC08_10440(mqnE)
DBA: Dbac_2962
DRT: Dret_0149
DSF: UWK_02735
DOG: HP555_10420(mqnE)
DBK: DGMP_16180(mqnE)
DOL: Dole_1271
DML: Dmul_31780(cofH)
DTO: TOL2_C34500(cofH)
DOV: DSCO28_01310(mqnE)
DWD: DSCW_12280(mqnE)
DALK: DSCA_05040(mqnE)
DLI: dnl_08230(cofH1)
DEK: DSLASN_15620(mqnE)
ADE: Adeh_0372
AORY: AMOR_20960(mqnE)
APAU: AMPC_32310(mqnE)
SFU: Sfum_3089
DAX: FDQ92_08525(mqnE)
DBR: Deba_2194
DHR: LGS26_06785(mqnE)
BSHI: LGQ02_17210(mqnE)
BHA: BH3411
BCL: ABC2933
BKW: BkAM31D_19845(mqnE_2)
ASED: IRT44_01985(mqnE)
SALE: EPH95_08990(mqnE)
SCIB: HUG20_16255(mqnE)
SCIA: HUG15_19185(mqnE)
AIA: AWH56_011005(mqnE)
BBEV: BBEV_0644
BSE: Bsel_1178
PSUA: FLK61_36675(mqnE)
SLMS: MM221_04535(mqnE)
HYI: K2M58_10705(mqnE) K2M58_10710(mqnE)
BRW: GOP56_13065(mqnE)
BCHS: JNE38_25725(mqnE)
BCOP: JD108_05055(mqnE)
PPY: PPE_03905
PPO: PPM_4103(M1_4511)
PPOL: X809_36635
PPOY: RE92_16725
PMW: B2K_05750
PLV: ERIC2_c29720(cofH2)
PSAB: PSAB_19705
PRI: PRIO_5647
PSON: JI735_03215(mqnE)
PSWU: SY83_00115
PLW: D5F53_02780(mqnE)
PLEN: EIM92_08800(mqnE)
PPSC: EHS13_08755(mqnE)
PLUT: EI981_23755(mqnE)
PALB: EJC50_10910(mqnE)
PBK: Back11_30130(mqnE)
PPRT: ET464_19395(mqnE)
PBAC: HUB98_11815(mqnE)
PRZ: GZH47_07645(mqnE)
PLYC: GXP70_08735(mqnE)
PSOP: KP014_26230(mqnE)
PTRI: KDC22_27580(mqnE)
PALO: E6C60_3453
PCEL: HUB94_21490(mqnE)
PTJ: JRJ22_24285(mqnE)
PALR: HGI30_18060(mqnE)
ASOC: CB4_01045(mqnE_1)
ATHE: K3F53_15455(mqnE)
COH: EAV92_01450(mqnE)
COHN: KCTCHS21_45070(mqnE)
CCHL: FPL14_06465(mqnE)
CHEB: HH215_13775(mqnE)
SACA: FFV09_06490(mqnE)
TVU: AB849_002130(mqnE)
PABS: JIR001_06960(mqnE_1) JIR001_06970(mqnE_2)
STH: STH817
CMIC: caldi_02180(mqnE_1) caldi_20340(mqnE_2)
SWO: Swol_1157
SLP: Slip_1167
SALQ: SYNTR_0718
SGY: Sgly_2856
PTH: PTH_0209(ThiH)
DRM: Dred_2195
DAE: Dtox_1643
DAU: Daud_1089
TFR: BR63_14140(mqnE)
HMO: HM1_1947
HCV: FTV88_1659(mqnE)
CTHM: CFE_1271
CHY: CHY_1806
MTA: Moth_1846
MTHO: MOTHE_c18760(mqnE)
MTHZ: MOTHA_c19560(mqnE)
ADG: Adeg_1450
TACI: TDSAC_0246
MHG: MHY_27660
MFUN: GXM21_06140(mqnE) GXM21_06145(mqnE)
MANA: MAMMFC1_02995(mqnE_1) MAMMFC1_03449(mqnE_3)
STED: SPTER_38990(mqnE)
SCO: SCO4494(SCD35.01)
SALB: XNR_3569
SMA: SAVERM_4813(cofH1)
SGR: SGR_4206
SGB: WQO_14525
SHY: SHJG_5673
SSOI: I1A49_25785(mqnE)
SFA: Sfla_3609
SBH: SBI_06076
SVE: SVEN_3124
STRP: F750_3111
SFI: SFUL_2949
SALU: DC74_3919
SALL: SAZ_20730
STRE: GZL_04979
SLD: T261_4549
STRM: M444_20155
SAMB: SAM23877_4308(mqnE)
SPRI: SPRI_3302
SRW: TUE45_05083(mqnE_2)
SLE: sle_31070(sle_31070)
SRN: A4G23_03229(mqnE_2)
SKY: D0C37_19480(mqnE)
SALW: CP975_20240(mqnE)
SGM: GCM10017557_47850(mqnE)
SPHW: NFX46_03035(mqnE)
STRD: NI25_16410
SLAU: SLA_3191
SALJ: SMD11_3743
SLX: SLAV_21775(mqnE3)
SFK: KY5_4605
SGE: DWG14_03600(mqnE)
SRJ: SRO_3180
SGD: ELQ87_16665(mqnE)
SQZ: FQU76_20070(mqnE)
SCYA: EJ357_26895(mqnE)
SNQ: CP978_19475(mqnE)
SKA: CP970_18415(mqnE)
SVN: CP980_14565(mqnE)
SNK: CP967_19810(mqnE)
SRK: FGW37_14725(mqnE)
SFIC: EIZ62_13650(mqnE)
SGAL: CP966_21140(mqnE)
SVR: CP971_19225(mqnE)
SFY: GFH48_18050(mqnE)
SAQU: EJC51_28155(mqnE)
SGF: HEP81_03391(mqnE)
SSEO: D0Z67_16710(mqnE)
SBY: H7H31_13750(mqnE)
SRIM: CP984_21700(mqnE)
SSUB: CP968_14640(mqnE)
SPHV: F9278_29850(mqnE)
SCIN: CP977_15085(mqnE)
SCHA: CP983_18235(mqnE)
SGX: H4W23_17575(mqnE)
SCOE: CP976_25100(mqnE)
SBAT: G4Z16_12975(mqnE)
SSPB: CP982_24300(mqnE)
SNF: JYK04_04971(mqnE)
SPLA: CP981_17925(mqnE)
SBRO: GQF42_25420(mqnE) GQF42_32270(mqnE)
STUI: GCM10017668_40660(mqnE)
SCHF: IPT68_20890(mqnE)
SHUN: DWB77_03357(mqnE)
SHAR: HUT13_10000(mqnE)
SCYG: S1361_22795(mqnE2)
SFEU: IM697_41415(mqnE)
SLIA: HA039_13980(mqnE)
SDW: K7C20_17110(mqnE)
SVD: CP969_22460(mqnE)
SCAL: I6J39_14105(mqnE)
SAUH: SU9_015290(mqnE) SU9_033115(mqnE)
SFB: CP974_17525(mqnE)
SMOB: J7W19_14540(mqnE)
SPRA: CP972_20685(mqnE)
SROI: IAG44_16745(mqnE)
SXN: IAG42_14905(mqnE)
SGJ: IAG43_18200(mqnE)
SHK: J2N69_21285(mqnE)
SANU: K7396_19735(mqnE) K7396_33670(mqnE)
STRY: EQG64_14170(mqnE)
SDD: D9753_14975(mqnE)
SGOB: test1122_15330(mqnE)
SINE: KI385_21060(mqnE)
SLF: JEQ17_26785(mqnE)
SDEC: L3078_27375(mqnE)
SAOV: G3H79_15425(mqnE)
SDUR: M4V62_19330(mqnE)
SYAN: NRK68_19535(mqnE)
SCT: SCAT_3453
KSK: KSE_33060
YIA: LO772_14780(mqnE)
STRH: GXP74_03985(mqnE)
ABRY: NYE86_32155(mqnE)
FAL: FRAAL1010
ACE: Acel_0259
SAQ: Sare_4505
MIL: ML5_0333
MICH: FJK98_01710(mqnE)
MTEM: GCE86_27245(mqnE)
MCAB: HXZ27_01780(mqnE)
MSAG: GCM10017556_29290(mqnE)
MCRA: ID554_11370(mqnE)
ASE: ACPL_421
AMS: AMIS_2050
ACTN: L083_0397
AFS: AFR_01470
ACTS: ACWT_0306
AIH: Aiant_44970(mqnE)
ACTR: Asp14428_43930(mqnE)
VER: HUT12_02310(mqnE)
PRY: Prubr_22350(mqnE)
CATI: CS0771_15980(mqnE)
DVC: Dvina_00765(mqnE) Dvina_31160(mqnE)
DFU: Dfulv_00800(mqnE) Dfulv_28960(mqnE)
DROS: Drose_00715(mqnE)
DAUR: Daura_00795(mqnE) Daura_29775(mqnE)
NHY: JQS43_01470(mqnE)
CCAZ: COUCH_38240(mqnE)
CAI: Caci_8066
SNA: Snas_0587
NAV: JQS30_01965(mqnE)
GLY: K3N28_06340(mqnE)
JTL: M6D93_02585(mqnE)
HAU: Haur_2163
DRA: DR_0366
DGE: Dgeo_2097
DFC: DFI_12970
DEIN: DAAJ005_15875(mqnE)
DGA: DEGR_29780(mqnE)
DPH: EHF33_07725(mqnE)
DRD: LMT64_10130(mqnE)
DRB: N0D28_06260(mqnE)
TRA: Trad_0908
TTH: TT_C0452
TTJ: TTHA0804(TTHA0804)
TAQ: TO73_1465
TANT: KNN15_08620(mqnE)
MRB: Mrub_0787
CTR: CT_426
CTA: CTA_0466
CTY: CTR_4271
CRA: CTO_0466
CTRQ: A363_00459
CTB: CTL0685
CTO: CTL2C_573
CTJ: JALI_4271
CTZ: CTB_4271
CSW: SW2_4341
CES: ESW3_4341
CTRB: BOUR_00455
CTEC: EC599_4401
CFS: FSW4_4341
CFW: FSW5_4341
CTFW: SWFP_4601
CTCH: O173_02335
CTRI: BN197_4321
CTRA: BN442_4321
CTCT: CTW3_02340
CMU: TC_0710
CMUR: Y015_03735
CMX: DNC_03590
CMZ: TAC_03735
CPN: CPn_0513
CPA: CP_0240
CPJ: CPj0513(CPj0513)
CPT: CpB0534
CPM: G5S_0559
CPEC: CPE3_0236
CPEO: CPE1_0236
CPER: CPE2_0236
CHB: G5O_0261
CHR: Cpsi_2431
CPSC: B711_0266
CPSN: B712_0259
CPSB: B595_0265
CPSG: B598_0260
CPSM: B602_0259
CPSI: B599_0258
CPSV: B600_0271
CPSW: B603_0259
CPST: B601_0258
CPSD: BN356_2381
CPSA: AO9_01235
CAV: M832_00620(cofH)
CCA: CCA_00230
CAB: CAB227
CABO: AB7_2531
CFE: BAE81548.1(CF0776)
CHLA: C834K_0249
CSUI: Chls_761(aminodeoxyfutalosine_synthase)
CSEE: C10C_0468
XII: AMD24_00441(mqnE_2)
MIN: Minf_1916(thiH)
MKC: kam1_401
MEAP: MTHMO_2006(mqnE)
VBS: EGM51_03005(mqnC)
RBA: RB2748
PSL: Psta_0917
PIR: VN12_23070(mqnE_2)
RUL: UC8_19200(mqnE_1)
RML: FF011L_21890(mqnE_2)
MFF: MFFC18_03410(mqnE_1)
ROL: CA51_40020(mqnE_2)
AHEL: Q31a_04840(mqnE_1)
LCRE: Pla8534_17400(mqnE_1)
AAGG: ETAA8_50360(mqnE_1)
BVO: Pan97_13950(mqnE_1)
RLC: K227x_22030(mqnE_2)
TTF: THTE_2437
AMUC: Pan181_05860(mqnE_1)
PND: Pla175_15020(mqnE_1)
AMOB: HG15A2_43540(mqnE_2)
PLM: Plim_0097
PEH: Spb1_08680(mqnE_1)
PLS: VT03_28800(mqnE_1)
PLH: VT85_20755(mqnE_2)
GMR: GmarT_50850(mqnE_2)
GPN: Pan110_52720(mqnE_2)
MRI: Mal4_30060(mqnE_2)
SDYN: Mal52_35610(mqnE_2)
PLON: Pla110_38330(mqnE_2)
GES: VT84_02115(mqnE_1)
FTJ: FTUN_3248
ULI: ETAA1_12950(mqnE_1)
TSPH: KIH39_00365(mqnE)
IPA: Isop_1895
SACI: Sinac_1135
PBOR: BSF38_04469(mqnE)
AGV: OJF2_56500(mqnE_2)
BPIT: BPIT_10430
JET: L3J17_07190(mqnE)
PCOR: KS4_21410(mqnE_2)
MCAD: Pan265_11320(mqnE_1)
HBS: IPV69_21595(mqnE)
ACA: ACP_0913
GRW: FTO74_05150(mqnE)
GRB: GOB94_15760(mqnE)
TALB: FTW19_14115(mqnE)
ABAS: ACPOL_0222
EDA: GWR55_07695(mqnE)
EDG: H7846_13275(mqnE)
ADIN: H7849_03885(mqnE)
ORP: MOP44_25890(mqnE)
SUS: Acid_1309
PFER: IRI77_06785(mqnE)
CHLO: J8C02_02820(mqnE)
THYD: TTHT_0590(mqnE)
FSC: FSU_2870
GAU: GAU_1634
GBA: J421_3267
AFD: Alfi_1359
AOK: A3BBH6_14110(mqnC-2)
ACOU: A5CBH24_12130(mqnC-2)
AIT: AI2BBH_14900(mqnE)
TTZ: FHG85_11080(mqnE)
BACC: BRDCF_p1368(cofH)
CPI: Cpin_4713
CHIT: FW415_14890(mqnE)
CHIH: GWR21_01295(mqnE)
COY: HF329_13800(mqnE)
CFIL: MYF79_15985(mqnE)
CHF: KTO58_12415(mqnE)
FGG: FSB75_03820(mqnE)
ARK: D6B99_13205(mqnE)
AGI: FSB73_12810(mqnE)
ARAC: E0W69_005745(mqnE)
ATEE: K9M52_12630(mqnE)
FLN: FLA_3666
PSEG: D3H65_03410(mqnE)
PGIN: FRZ67_04170(mqnE)
PGO: FSB84_27780(mqnE)
FLS: GLV81_10245(mqnE)
LACS: H4075_09750(mqnE)
FEI: K9M53_07335(mqnE)
FLP: LK994_13040(mqnE)
FLC: KJS93_08830(mqnE)
FLV: KJS94_06925(mqnE)
SEDT: TEGAF0_05530(mqnC-2)
SGN: SGRA_3725
PHE: Phep_1880
PEJ: FYC62_07435(mqnE)
PEK: FFJ24_007745(mqnE)
PROE: H9L23_09185(mqnE)
PEX: IZT61_01845(mqnE)
PMUO: LOK61_07260(mqnE)
SPSC: E2P86_09140(mqnE)
SPHZ: E3D81_13170(mqnE)
SPHE: GFH32_06720(mqnE)
SPDR: G6053_09275(mqnE)
SSPI: I6J01_13800(mqnE)
SMUI: I6J00_08175(mqnE)
SSIY: JVX97_11765(mqnE)
MUC: MuYL_2738
MGOT: MgSA37_02948(mqnE_2)
MUH: HYN43_009490(mqnE)
MGIN: FRZ54_17480(mqnE)
MGK: FSB76_30905(mqnE)
MRUB: DEO27_010040(mqnE)
MGOS: DIU38_010635(mqnE)
MMAB: HQ865_09370(mqnE)
MGIK: GO620_006870(mqnE)
MDJ: LLH06_13410(mqnE)
MROB: HH214_20515(mqnE)
AGD: FRZ59_13255(mqnE)
OLI: FKG96_14680(mqnE)
AAE: aq_648
HTH: HTH_1238
TAL: Thal_0761
TTK: TST_1168
GTL: EP073_12060(mqnE)
MSCH: N508_000830(mqnE)
CABY: Cabys_3286(mqnE)
DTP: JZK55_02930(mqnE)
THET: F1847_05655(mqnE)
TAV: G4V39_03365(mqnE)
TMAI: FVE67_01015(mqnE)
NLI: G3M70_17655(mqnE)
MOX: DAMO_1584
FPL: Ferp_1892
GAC: GACE_1763
GAH: GAH_00871
TVO: TVG1448112(TVG1448112)
FAI: FAD_1708
CDIV: CPM_0509
ACJ: ACAM_0191
IHO: Igni_1086
IIS: EYM_01165
IPC: IPA_03555
PIS: Pisl_1325
PCL: Pcal_0738
PAS: Pars_0220
PYR: P186_2546
POG: Pogu_2263
TNE: Tneu_0222
CMA: Cmaq_1417
TTN: TTX_1950(thiH)
TUZ: TUZN_1542
VDI: Vdis_0278
VMO: VMUT_1357
NMR: Nmar_0742
NCT: NMSP_0686(cofH_1)
NGA: Ngar_c27070(cofH3)
NVN: NVIE_015990(cofH2)
NEV: NTE_00789
TAA: NMY3_02629(mqnE_2)
NFN: NFRAN_0237(mqnE)
NCV: NCAV_1093(mqnE)
NBV: T478_0614
NDV: NDEV_1291
CCAI: NAS2_0521
 » show all
Reference
  Authors
Mahanta N, Fedoseyenko D, Dairi T, Begley TP
  Title
Menaquinone biosynthesis: formation of aminofutalosine requires a unique radical SAM enzyme.
  Journal
J Am Chem Soc 135:15318-21 (2013)
DOI:10.1021/ja408594p
  Sequence
[sco:SCO4494] [ttj:TTHA0804]

KEGG   ENZYME: 2.5.1.120
Entry
EC 2.5.1.120                Enzyme                                 
Name
aminodeoxyfutalosine synthase;
MqnE;
AFL synthase;
aminofutalosine synthase;
S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (HCO3--hydrolysing, 6-amino-6-deoxyfutalosine-forming)
Reaction(IUBMB)
S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate + H2O = 6-amino-6-deoxyfutalosine + L-methionine + HCO3- [RN:R10667]
Reaction(KEGG)
R10667
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3-[(1-carboxyvinyl)oxy]benzoate [CPD:C20772];
H2O [CPD:C00001]
Product
6-amino-6-deoxyfutalosine [CPD:C20773];
L-methionine [CPD:C00073];
HCO3- [CPD:C00288]
Comment
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the transferred adenosyl group. The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis.
History
EC 2.5.1.120 created 2014
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K18285  aminodeoxyfutalosine synthase
Genes
HPYHP_0654
HEOC694_03380
HPJjhp_0599
HPAHPAG1_0639
HPSHPSH_03585
HHPHPSH112_03740
HHQHPSH169_03355
HHRHPSH417_03165
HPGHPG27_616
HPPHPP12_0667
HPBHELPY_0717
HPLHPB8_857
HPCHPPC_03515
HCAHPPC18_03165
HPMHPSJM_03330
HPEHPELS_03265
HPOHMPREF4655_20946
HPIhp908_0667
HPQhp2017_0644
HPWhp2018_0645
HPUHPCU_03550
HEFHPF16_0663
HPFHPF30_0674
HEQHPF32_0665
HEXHPF57_0677
HPTHPSAT_03515
HPZHPKB_0690
HPVHPV225_0662
HPXHMPREF0462_0713
HENHPSNT_03370
HPHHPLT_03270
HEGHPGAM_03375
HPNHPIN_03370
HEPHPPN120_03440
HEUHPPN135_03230
HESHPSA_03095
HPYSHPSA20_0683
HCNHPB14_03400
HPDKHP_0667
HEYMWE_0854
HERC695_03385
HEIC730_03385
HPYAHPAKL117_03100
HPYKHPAKL86_04235
HPYOHPOK113_0668
HPYLHPOK310_0648
HPYBHPOKI102_03740
HPYCHPOKI112_03770
HPYDHPOKI128_03120
HPYEHPOKI154_03345
HPYFHPOKI422_03745
HPYGHPOKI673_03325
HPYHHPOKI828_03335
HPYJHPOKI898_03740
HPYRK747_07365
HPYIK750_05585
HPYUK751_04110
HPYMK749_02000
HEMK748_00485
HEBU063_0958
HEZU064_0962
HHEHH_1021
HACHac_0839
HMSHMU06060
HFEHFELIS_02460
HBIHBZC1_18300
HCEHCW_05760
HCMHCD_05315
HCPHCN_0074
HCBHCBAA847_0068
HHMBN341_4610
HTYBN2458_PEG1864
HBLXJ32_01345
HADCDV25_02645
HETBBW65_04645
HCLNCTC13205_00985
HWIA0Z60_03060(mqnE)
HSHNHP194022_16570(mqnE)
WSUWS2177
TDNSuden_1475
SUASaut_1516
SULNFJR47_06880(mqnE)
SULGFJR48_03675(mqnE)
SULCCVO_02635(mqnE)
SPALFM071_07125(mqnE)
SSEIFJR45_04310(mqnE)
SBALHUE88_02945(mqnE)
SMASHUE87_09410(mqnE)
SKUSulku_0663
SULRB649_03315
CJECj1368
CJBBN148_1368
CJJCJJ81176_1370
CJUC8J_1287
CJNICDCCJ07001_1303
CJICJSA_1302
CJMCJM1_1328
CJSCJS3_1466
CJPA911_06645
CJEJN564_01364
CJEUN565_01404
CJENN755_01401
CJEIN135_01456
CJERH730_07805
CJVMTVDSCj20_1349
CJYQZ67_01505(mqnE_2)
CJQUC78_1315(mqnE_2)
CJLPJ17_07235
CJWPJ18_07020
CJRCJE1560
CJDJJD26997_0282
CJZM635_02540
CJXBN867_13530
CFFCFF8240_0584
CFTCFF04554_0578
CFVCFVI03293_0581
CFXCFV97608_0631
CFZCSG_2310
CAMPCFT03427_0588
CFPCR44_02995
CCVCCV52592_0220
CHACHAB381_0832
CCOCCC13826_1483
CCOCCCON33237_1219
CLACLA_0427
CLRUPTC16701_0423
CLMUPTC16712_0429
CLQUPTC4110_0423
CLNUPTC3659_0447
CLLCONCH_0430
CCOLBN865_07710c
CCCG157_01990
CCQN149_1332(mqnE)
CCFYSQ_02015
CCYYSS_07410
CCOIYSU_02050
CCOFVC76_06860(mqnE_2)
CCOOATE51_00826(mqnE_1)
CAJCIG1485E_0636
CISCINS_0406
CVOCVOL_0417
CPELCPEL_0436
CAMRCAQ16704_0443
CSMCSUB8521_0459
CSFCSUB8523_0445
CGRACGRAC_1021
CURECUREO_1051
CHYOCHH_0511
CHVCHELV3228_0365
CSPFCSF_0597
CPINCPIN18020_0481
CCUNCCUN_1423
CLXCLAN_0672
CAVICAV_1189
CHWA2J15_004620(mqnE)
CAMZCVIC12175_0662
CAMYCSUIS_0728
COJCORN_0434
CUXCUP3940_1281
CRXCRECT_0724
CGEOCGEO_1102
CCORCCORG_0672
CARMCARM_0411
CMUCCMCT_0624
CSHOCSHOW_1378
CINFCINF_0853
CNVCNZW441b_1235
SDLSdel_1686
SBASulba_1761
SMULSMUL_2362
SHALSHALO_2108
SULSSdiek1_2175
SULJSJPD1_2127
SULTFA592_03180(mqnE)
ABUAbu_0251
ABTABED_0234
ABLA7H1H_0253
ASKEI285_08550(mqnE)
ATPATR_0180
ACIBACBT_1955
ACREACRYA_1762
ALANALANTH_0302
APOCAPORC_1850
AFCAFAEC_1989
ATHRATH_1745
ANTArnit_2823
AELLAELL_0398
AAQIAAQM_0315
ASUIASUIS_0323
ACLOACLO_0374
AVPAVENP_0385
ADZADFLV_0399
ARCABLL_0385
PACOAACT_0429
ALKALEK_3080
ALPLPB137_12420
AHSAHALO_2376
AMYTAMYT_2431
AMARAMRN_2478
ACAAACAN_2465
AMOLAMOL_2449
APAIAPAC_2268
HBVABIV_2310
HEBRAEBR_2684
AANAAANAER_2627
HYONNO_1448
NSANitsa_0571
SUNSUN_0538
SLHYH65_08455
SINUIMZ28_08270(mqnE)
NISNIS_0648
NAMNAMH_1275
NAPC3L23_06710
CMEDFE773_03450(mqnE)
CPAFC6V80_07275(mqnE)
GSUGSU0441(mqnC-2)
GSKKN400_0416(mqnC-2)
GMEGmet_3391(mqnC-2)
GPIGPICK_15520
GAOA2G06_02045
GBZJZM60_06560(mqnE)
GEMGM21_0218
GEBGM18_0263
GEFFO488_00965(mqnE)
GURGura_4284
GEOGeob_0418(mqnC-2)
GLOGlov_0625
GBMGbem_0234(mqnC-2)
GBNGEOBRER4_02290(mqnC-2)
GSBGSUB_15775
GERKP004_17930(mqnE)
GSUBKP001_15300(mqnE)
GNTKP003_21020(mqnE)
GPLM1B72_20780(mqnE)
PCAPcar_0319(mqnC-2)
PACEA6070_14130
PEFA7E78_11905
PPDPpro_3578
DESDSOUD_0278(mqnC-2)
DEUDBW_0510
DVEDESUT3_01690(mqnC-2)
DEPAOP6_0162(mqnC-2)
DVUDVU_2756
DVLDvul_0551
DVMDvMF_1188
DVGDeval_2547
DDSDdes_1279
DFIAXF13_03250
DPGDESPIGER_2583
DEFCNY67_07310
DTRRSDT_0540(mqnE)
DFLDFE_3185
DSDGD606_09000
DMADMR_08720
DCBC3Y92_16115
DGGDGI_2623
DDEDde_0798
DMSE8L03_14105(mqnE)
DSADesal_1216
DHYDESAM_22965
DAFDesaf_1722
DASDaes_2223
DPIBN4_20498
PPRFDPRO_3994(mqnE)
PSELGM415_11850(mqnE)
DDNDND132_3431
PSEFPSDVSF_35170(mqnE)
DSXGD604_01550
PBIZLWC08_10440(mqnE)
DBADbac_2962
DOAAXF15_03590
DRTDret_0149
DSFUWK_02735
DAKDaAHT2_0566
DPRDespr_1800
DEOCAY53_06255
DOGHP555_10420(mqnE)
DBKDGMP_16180(mqnE)
DOLDole_1271
DMLDmul_31780(cofH)
DTOTOL2_C34500(cofH)
DOVDSCO28_01310(mqnE)
DWDDSCW_12280(mqnE)
DALKDSCA_05040(mqnE)
DLIdnl_08230(cofH1)
DMMdnm_058280
DEKDSLASN_15620(mqnE)
ADEAdeh_0372
ACPA2cp1_0401
AFWAnae109_4206
ANKAnaeK_0400
AORYAMOR_20960(mqnE)
APAUAMPC_32310(mqnE)
VINAKJ08_0219
LLUAKJ09_06555
DAODesac_1411
SFUSfum_3089
DAXFDQ92_08525(mqnE)
DBRDeba_2194
HMRHipma_0825
DAVDESACE_01580
DHRLGS26_06785(mqnE)
BSHILGQ02_17210(mqnE)
BCOBcell_3405
BHABH3411
BCLABC2933
BLEBleG1_2931
BKWBkAM31D_19845(mqnE_2)
BPFBpOF4_04830
ASEDIRT44_01985(mqnE)
FPNABE65_016500
FARABE41_015470
RUEDT065_08895
SALEEPH95_08990(mqnE)
SCIBHUG20_16255(mqnE)
SCIAHUG15_19185(mqnE)
AIAAWH56_011005(mqnE)
BBEVBBEV_0644
BSEBsel_1178
PSUAFLK61_36675(mqnE)
SLMSMM221_04535(mqnE)
HYIK2M58_10705(mqnE) K2M58_10710(mqnE)
BBEBBR47_47720
BLRBRLA_c040840
BFMBP422_19660
BAGRBA6348_07620
BRWGOP56_13065(mqnE)
BCHSJNE38_25725(mqnE)
BCOPJD108_05055(mqnE)
PJDPjdr2_4851
GYMGYMC10_5458
PPYPPE_03905
PPMPPSC2_20480
PPOPPM_4103(M1_4511)
PPOLX809_36635
PPQPPSQR21_041410
PPOYRE92_16725
PMSKNP414_03735
PMQPM3016_1130
PMWB2K_05750
PTAHPL003_01475
PLVERIC2_c29720(cofH2)
PSABPSAB_19705
PDUPDUR_22270
PBDPBOR_30120
PGMPGRAT_27000
PODPODO_25745
PAENP40081_31665
PAEFR50345_25675
PAEQR50912_28520
PSTEPSTEL_22320
PAEAR70723_27240
PAEER70331_26320
PAEHH70357_29085
PAEJH70737_25480
PBJVN24_15850
PIHUB51_01690
PRIPRIO_5647
PSONJI735_03215(mqnE)
PPEOABE82_20545
PNPIJ22_03070
POWIJ21_13570
PBVAR543_20665
PXLBS614_28400
PYGAWM70_14350
PSWUSY83_00115
PDHB9T62_26245
PIBBBD41_18865
PCXLPB68_07050
PKBB4V02_04835
PAIHASL14_17355
PVOPVOR_29504
PLWD5F53_02780(mqnE)
PLENEIM92_08800(mqnE)
PPSCEHS13_08755(mqnE)
PLUTEI981_23755(mqnE)
PALBEJC50_10910(mqnE)
PCHIPC41400_25520
PBKBack11_30130(mqnE)
PPRTET464_19395(mqnE)
PBACHUB98_11815(mqnE)
PRZGZH47_07645(mqnE)
PLYCGXP70_08735(mqnE)
PSOPKP014_26230(mqnE)
PTRIKDC22_27580(mqnE)
PALOE6C60_3453
PCELHUB94_21490(mqnE)
PTJJRJ22_24285(mqnE)
PALRHGI30_18060(mqnE)
TCOTheco_0872
ANXACH33_03460
ASOCCB4_01045(mqnE_1)
ATHEK3F53_15455(mqnE)
COHEAV92_01450(mqnE)
COHNKCTCHS21_45070(mqnE)
CCHLFPL14_06465(mqnE)
CHEBHH215_13775(mqnE)
SACAFFV09_06490(mqnE)
BTSBtus_0514 Btus_1478 Btus_1757
KYRCVV65_04040 CVV65_07730 CVV65_08990
TUMCBW65_19810
TABCIG75_09645
LFBC1X05_03220
TVUAB849_002130(mqnE)
PABSJIR001_06960(mqnE_1) JIR001_06970(mqnE_2)
STHSTH817
CMICcaldi_02180(mqnE_1) caldi_20340(mqnE_2)
SWOSwol_1157
SLPSlip_1167
SALQSYNTR_0718
SGYSgly_2856
DORDesor_1299 Desor_3397
DAIDesaci_1904 Desaci_1922
DMIDesmer_1198 Desmer_2662
DCADesca_1586
PTHPTH_0209(ThiH)
DRMDred_2195
DRUDesru_1561
DAEDtox_1643
DKUDesku_1550
DAUDaud_1089
TFRBR63_14140(mqnE)
AACXDEACI_1819 DEACI_2410
TJRTherJR_1772
DGIDesgi_2116
HMOHM1_1947
HCVFTV88_1659(mqnE)
CTHMCFE_1271
CHYCHY_1806
MTAMoth_1846
MTHOMOTHE_c18760(mqnE)
MTHZMOTHA_c19560(mqnE)
ADGAdeg_1450
TNRThena_0254
TACITDSAC_0246
AARAcear_0507
SSGSelsp_0312 Selsp_2220
SRISELR_27040 SELR_27050
SELEADJ74_05060 ADJ74_05100
SELOAXE86_04795 AXE86_04855
SELTBCS37_01090 BCS37_01135
MHGMHY_27660
MFUNGXM21_06140(mqnE) GXM21_06145(mqnE)
PUFUFO1_1286 UFO1_4449
PFTJBW_00026 JBW_02992
MANAMAMMFC1_02995(mqnE_1) MAMMFC1_03449(mqnE_3)
STEDSPTER_38990(mqnE)
SCOSCO4494(SCD35.01)
SALBXNR_3569
SMASAVERM_4813(cofH1)
SGRSGR_4206
SGBWQO_14525
SCBSCAB_38341
SSXSACTE_2714
SVLStrvi_0750
SHYSHJG_5673
SHOSHJGH_5434
SRCM271_22260
SMALSMALA_0018 SMALA_4340
SSOII1A49_25785(mqnE)
SFASfla_3609
SBHSBI_06076
SVESVEN_3124
SDVBN159_3892
SALSSLNWT_0689 SLNWT_2736
STRPF750_3111
SFISFUL_2949
SCIB446_21370
SALUDC74_3919
SALLSAZ_20730
SLVSLIV_15805
SGUSGLAU_19505
SVTSVTN_16290
STREGZL_04979
SCWTU94_18875
SLDT261_4549
SLCSL103_01690
SXISXIM_22210
STRMM444_20155
STRCAA958_20480
SAMBSAM23877_4308(mqnE)
SPRISPRI_3302
SCZABE83_21210
SCXAS200_21095
SRWTUE45_05083(mqnE_2)
STRFASR50_20625
SLEsle_31070(sle_31070)
SRNA4G23_03229(mqnE_2)
SPAVSpa2297_18860
STRTA8713_18065
SCLFBB341_10940
SGSAVL59_03490
STSIA4E84_23385
SKYD0C37_19480(mqnE)
SALWCP975_20240(mqnE)
SGMGCM10017557_47850(mqnE)
SCADDN051_17580
SPHWNFX46_03035(mqnE)
SLSSLINC_4907
SNRSNOUR_22775
SPLULK06_013020
STRDNI25_16410
SNWBBN63_13510
SAUOBV401_25545
SSIAA7J05_15750
SVUB1H20_13865
SPUNBFF78_18360
SGVB1H19_19435
SLAUSLA_3191
SALFSMD44_05000
SALJSMD11_3743
SLXSLAV_21775(mqnE3)
STROSTRMOE7_18175
SFKKY5_4605
SNZDC008_20040
SGEDWG14_03600(mqnE)
SRJSRO_3180
SLKSLUN_23200
SDXC4B68_17050
SGDELQ87_16665(mqnE)
SQZFQU76_20070(mqnE)
SCYAEJ357_26895(mqnE)
SASTCD934_17715
SNQCP978_19475(mqnE)
STIRDDW44_17370
SKACP970_18415(mqnE)
SGZC0216_02340
SVNCP980_14565(mqnE)
SNKCP967_19810(mqnE)
SHAWCEB94_23735
SRKFGW37_14725(mqnE)
SFICEIZ62_13650(mqnE)
SGALCP966_21140(mqnE)
SSPODDQ41_18420
SVRCP971_19225(mqnE)
SPADDVK44_12585
SFYGFH48_18050(mqnE)
SAQUEJC51_28155(mqnE)
SGFHEP81_03391(mqnE)
SCAVCVT27_13385
SSEOD0Z67_16710(mqnE)
SBYH7H31_13750(mqnE)
SRIMCP984_21700(mqnE)
SSUBCP968_14640(mqnE)
SPHVF9278_29850(mqnE)
SCINCP977_15085(mqnE)
SFUGCNQ36_20170
SPACB1H29_15900
STSUB7R87_19635
SCHACP983_18235(mqnE)
SGXH4W23_17575(mqnE)
SCOECP976_25100(mqnE)
SBATG4Z16_12975(mqnE)
SSPBCP982_24300(mqnE)
SNFJYK04_04971(mqnE)
SPLACP981_17925(mqnE)
SBROGQF42_25420(mqnE) GQF42_32270(mqnE)
STUIGCM10017668_40660(mqnE)
SATAC5746_18140
SCHFIPT68_20890(mqnE)
SHUNDWB77_03357(mqnE)
SHARHUT13_10000(mqnE)
SCYGS1361_22795(mqnE2)
SFEUIM697_41415(mqnE)
SLIAHA039_13980(mqnE)
SDWK7C20_17110(mqnE)
SVDCP969_22460(mqnE)
SCALI6J39_14105(mqnE)
SAUHSU9_015290(mqnE) SU9_033115(mqnE)
SFBCP974_17525(mqnE)
SMOBJ7W19_14540(mqnE)
SPRACP972_20685(mqnE)
SPEUCGZ69_20490
SROIIAG44_16745(mqnE)
SXNIAG42_14905(mqnE)
SGJIAG43_18200(mqnE)
SHKJ2N69_21285(mqnE)
SANUK7396_19735(mqnE) K7396_33670(mqnE)
STRYEQG64_14170(mqnE)
SDDD9753_14975(mqnE)
SACTDMT42_22585
SMAOCAG99_10800
SGOBtest1122_15330(mqnE)
SINEKI385_21060(mqnE)
SLFJEQ17_26785(mqnE)
SDECL3078_27375(mqnE)
SAOVG3H79_15425(mqnE)
SDURM4V62_19330(mqnE)
SYANNRK68_19535(mqnE)
SCTSCAT_3453
SCYSCATT_34390
KSKKSE_33060
KABB7C62_13925
KAUB6264_13865
KITCFP65_3043
STRIC7M71_017855 C7M71_025805
YIALO772_14780(mqnE)
STRHGXP74_03985(mqnE)
ABRYNYE86_32155(mqnE)
FRAFrancci3_0519
FREFranean1_6111
FRIFraEuI1c_6291
FALFRAAL1010
FSYFsymDg_4024
ACEAcel_0259
STPStrop_4085
SAQSare_4505
MAUMicau_0360
MILML5_0333
MICBMicB006_0371
MTUACSH63_23465
MICHFJK98_01710(mqnE)
MTEMGCE86_27245(mqnE)
MCABHXZ27_01780(mqnE)
MSAGGCM10017556_29290(mqnE)
VMAVAB18032_05970
MCRAID554_11370(mqnE)
ASEACPL_421
AMSAMIS_2050
ACTNL083_0397
AFSAFR_01470
ACTSACWT_0306
AIHAiant_44970(mqnE)
ACTRAsp14428_43930(mqnE)
PLKCIK06_01885
PLABC6361_18685
PLATC6W10_28375
VERHUT12_02310(mqnE)
ASERAsera_19140
PRYPrubr_22350(mqnE)
CATICS0771_15980(mqnE)
DVCDvina_00765(mqnE) Dvina_31160(mqnE)
DFUDfulv_00800(mqnE) Dfulv_28960(mqnE)
DROSDrose_00715(mqnE)
DAURDaura_00795(mqnE) Daura_29775(mqnE)
NHYJQS43_01470(mqnE)
CCAZCOUCH_38240(mqnE)
CAICaci_8066
SNASnas_0587
NAVJQS30_01965(mqnE)
GLYK3N28_06340(mqnE)
JTLM6D93_02585(mqnE)
HAUHaur_2163
DRADR_0366
DGEDgeo_2097
DDRDeide_22460
DMRDeima_2581
DPTDeipr_1946
DGODGo_CA2378
DPDDeipe_2671
DSWQR90_01395
DCHSY84_07900
DABAUC44_14910
DPUSU48_13645
DEZDKM44_04190
DWUDVJ83_12995
DFCDFI_12970
DEINDAAJ005_15875(mqnE)
DGADEGR_29780(mqnE)
DPHEHF33_07725(mqnE)
DRDLMT64_10130(mqnE)
DRBN0D28_06260(mqnE)
TRATrad_0908
TTHTT_C0452
TTJTTHA0804(TTHA0804)
TTSThthe16_0809
TTLTtJL18_1247
TSCTSC_c07250
THCTCCBUS3UF1_8200
TOSTheos_0580
TAQTO73_1465
TPARAV541_06710
TBCA0O31_01722
TANTKNN15_08620(mqnE)
MRBMrub_0787
MREK649_03570
MSVMesil_1525
MTAIMtai_v1c05070
OPROcepr_1306
MHDMarky_1483
CCZCCALI_00141
FGIOP10G_0491
NPYNPRO_25300
CTRCT_426
CTDCTDEC_0426
CTFCTDLC_0426
CTRDSOTOND1_00452
CTROSOTOND5_00450
CTRTSOTOND6_00449
CTACTA_0466
CTYCTR_4271
CRACTO_0466
CTRQA363_00459
CTRXA5291_00458
CTRZA7249_00457
CTRPL11322_00445
CTLJL1115_00445
CTLXL1224_00445
CTLLL1440_00448
CTBCTL0685
CTRRL225667R_00447
CTLFCTLFINAL_03570
CTLICTLINITIAL_03560
CTLCTLon_0681
CTRUL2BUCH2_00444
CTRLL2BLST_00444
CTRVL2BCV204_00444
CTRML2BAMS1_00444
CTLAL2BAMS2_00444
CTLML2BAMS3_00444
CTLSL2BAMS4_00445
CTLZL2BAMS5_00445
CTLCL2BCAN1_00445
CTLNL2BCAN2_00445
CTLBL2B795_00445
CTLQL2B8200_00444
CTOCTL2C_573
CTRNL3404_00445
CTJJALI_4271
CTZCTB_4271
CTGE11023_02220
CTKE150_02235
CSWSW2_4341
CESESW3_4341
CTRBBOUR_00455
CTRESOTONE4_00450
CTRSSOTONE8_00456
CTECEC599_4401
CFSFSW4_4341
CFWFSW5_4341
CTFWSWFP_4601
CTRFSOTONF3_00450
CTCHO173_02335
CTNG11074_02210
CTQG11222_02210
CTVCTG9301_02215
CTWG9768_02205
CTRGSOTONG1_00451
CTRIBN197_4321
CTRABN442_4321
CTRHSOTONIA1_00452
CTRJSOTONIA3_00452
CTRKSOTONK1_00449
CTJTCTJTET1_02235
CTCFCTRC69_02245
CTFSCTRC342_02255
CTHFCTRC852_02270
CTCJCTRC943_02215
CTHJCTRC953_02215
CTMJCTRC966_02230
CTTJCTRC971_02220
CTJSCTRC122_02250
CTRCCTRC55_02230
CTRWCTRC3_02255
CTRYCTRC46_02230
CTCTCTW3_02340
CMUTC_0710
CMURY015_03735
CMNBB17_03785
CMMNC80_03565
CMGNC81_03585
CMXDNC_03590
CMZTAC_03735
CPNCPn_0513
CPACP_0240
CPJCPj0513(CPj0513)
CPTCpB0534
CLPCPK_ORF01028
CPMG5S_0559
CPECCPE3_0236
CPEOCPE1_0236
CPERCPE2_0236
CHPCPSIT_0256
CHBG5O_0261
CHSCPS0A_0262
CHICPS0B_0258
CHTCPS0D_0259
CHCCPS0C_0260
CHRCpsi_2431
CPSCB711_0266
CPSNB712_0259
CPSBB595_0265
CPSGB598_0260
CPSMB602_0259
CPSIB599_0258
CPSVB600_0271
CPSWB603_0259
CPSTB601_0258
CPSDBN356_2381
CPSAAO9_01235
CAVM832_00620(cofH)
CCACCA_00230
CABCAB227
CABOAB7_2531
CFEBAE81548.1(CF0776)
CGZM787_003085
CHLAC834K_0249
CSUIChls_761(aminodeoxyfutalosine_synthase)
CBUEHBN95_04315
CSEEC10C_0468
XIIAMD24_00441(mqnE_2)
MINMinf_1916(thiH)
MKCkam1_401
MEAPMTHMO_2006(mqnE)
VBSEGM51_03005(mqnC)
RBARB2748
PSLPsta_0917
PIRVN12_23070(mqnE_2)
RULUC8_19200(mqnE_1)
RMLFF011L_21890(mqnE_2)
MFFMFFC18_03410(mqnE_1)
ROLCA51_40020(mqnE_2)
AHELQ31a_04840(mqnE_1)
LCREPla8534_17400(mqnE_1)
AAGGETAA8_50360(mqnE_1)
BVOPan97_13950(mqnE_1)
RLCK227x_22030(mqnE_2)
TTFTHTE_2437
LPAVPLANPX_4481
AMUCPan181_05860(mqnE_1)
PNDPla175_15020(mqnE_1)
AMOBHG15A2_43540(mqnE_2)
PLMPlim_0097
PEHSpb1_08680(mqnE_1)
PBSPlabr_1336
PLSVT03_28800(mqnE_1)
PLHVT85_20755(mqnE_2)
FMRFuma_00537
GMRGmarT_50850(mqnE_2)
GPNPan110_52720(mqnE_2)
MRIMal4_30060(mqnE_2)
SDYNMal52_35610(mqnE_2)
PLONPla110_38330(mqnE_2)
GESVT84_02115(mqnE_1)
GOGC1280_34545
GMSSOIL9_76670
TIMGMBLW1_36960
LRSPX52LOC_05718
FTJFTUN_3248
ULIETAA1_12950(mqnE_1)
TSPHKIH39_00365(mqnE)
IPAIsop_1895
SACISinac_1135
PBORBSF38_04469(mqnE)
AGVOJF2_56500(mqnE_2)
KSTKSMBR1_1675
BPITBPIT_10430
JETL3J17_07190(mqnE)
PHMPSMK_11680
PCORKS4_21410(mqnE_2)
MCADPan265_11320(mqnE_1)
HBSIPV69_21595(mqnE)
ABAAcid345_0584
ACAACP_0913
ACMAciX9_2267
GMAAciX8_3319
GRWFTO74_05150(mqnE)
GRBGOB94_15760(mqnE)
TSAAciPR4_4026
TRSTerro_1502
TALBFTW19_14115(mqnE)
ABASACPOL_0222
EDAGWR55_07695(mqnE)
EDGH7846_13275(mqnE)
ADINH7849_03885(mqnE)
ORPMOP44_25890(mqnE)
SUSAcid_1309
PFERIRI77_06785(mqnE)
CTMCabther_A0580
CHLOJ8C02_02820(mqnE)
ABACLuPra_00778 LuPra_04444
THYDTTHT_0590(mqnE)
FSUFisuc_2321
FSCFSU_2870
GAUGAU_1634
GGRHKW67_05875
GBAJ421_3267
AFDAlfi_1359
ALDGFH31_09870
AOKA3BBH6_14110(mqnC-2)
ACOUA5CBH24_12130(mqnC-2)
AITAI2BBH_14900(mqnE)
AIUNQ491_08260
RBCBN938_0143
TTZFHG85_11080(mqnE)
BLQL21SP5_00688
BACCBRDCF_p1368(cofH)
CPICpin_4713
CBAECOR50_18635
CHITFW415_14890(mqnE)
CHIHGWR21_01295(mqnE)
COYHF329_13800(mqnE)
CFILMYF79_15985(mqnE)
CHFKTO58_12415(mqnE)
NKONiako_1021
NSONIASO_00465
NIAA8C56_13140
FLASY85_04225
FGGFSB75_03820(mqnE)
ARBA9P82_05275
ARKD6B99_13205(mqnE)
AGIFSB73_12810(mqnE)
ARACE0W69_005745(mqnE)
ATEEK9M52_12630(mqnE)
FLNFLA_3666
PSEGD3H65_03410(mqnE)
PGINFRZ67_04170(mqnE)
PGOFSB84_27780(mqnE)
FLSGLV81_10245(mqnE)
LACSH4075_09750(mqnE)
FEIK9M53_07335(mqnE)
FLPLK994_13040(mqnE)
FLCKJS93_08830(mqnE)
FLVKJS94_06925(mqnE)
SEDTTEGAF0_05530(mqnC-2)
HHYHalhy_5958
SGNSGRA_3725
AUPAsAng_0009420
PHEPhep_1880
PEPAQ505_09310
PCMAY601_1708
PSTYBFS30_26500
PGSCPT03_09475
PEJFYC62_07435(mqnE)
PEKFFJ24_007745(mqnE)
PROEH9L23_09185(mqnE)
PEXIZT61_01845(mqnE)
PMUOLOK61_07260(mqnE)
PSNPedsa_1153
SHGSph21_3379
SHTKO02_12810
SPHNBV902_19790
SMIZ4412673_01833
SPSCE2P86_09140(mqnE)
SPHZE3D81_13170(mqnE)
SPHEGFH32_06720(mqnE)
SPDRG6053_09275(mqnE)
SDJNCTC13534_02546
STHANCTC11429_05114
SSPII6J01_13800(mqnE)
SMUII6J00_08175(mqnE)
SSIYJVX97_11765(mqnE)
SCNSolca_1863
MUPA0256_19215
MUCMuYL_2738
MGOTMgSA37_02948(mqnE_2)
MUHHYN43_009490(mqnE)
MGINFRZ54_17480(mqnE)
MGKFSB76_30905(mqnE)
MRUBDEO27_010040(mqnE)
MGOSDIU38_010635(mqnE)
MMABHQ865_09370(mqnE)
MGIKGO620_006870(mqnE)
MDJLLH06_13410(mqnE)
MROBHH214_20515(mqnE)
AGDFRZ59_13255(mqnE)
OLIFKG96_14680(mqnE)
SBXCA265_08200
AAEaq_648
HYAHY04AAS1_0810
HHOHydHO_0805
HYSHydSN_0822
HTHHTH_1238
HTEHydth_1230
TALThal_0761
TRDTHERU_02910
SULSYO3AOP1_1499
SAFSULAZ_0984
PMXPERMA_0871
TTKTST_1168
TAMTheam_0969 Theam_0970
DTEDester_0260 Dester_0261
DINSelin_2420
DDFDEFDS_1711
DAPDacet_1842
GTLEP073_12060(mqnE)
CNICalni_1638
FSIFlexsi_1895
MSCHN508_000830(mqnE)
CABYCabys_3286(mqnE)
TYETHEYE_A1742
DTPJZK55_02930(mqnE)
TIDThein_1226
TOPTOPB45_0506
TCMHL41_03805
THETF1847_05655(mqnE)
CTHITHC_1484 THC_1560
TAVG4V39_03365(mqnE)
TMAIFVE67_01015(mqnE)
NLIG3M70_17655(mqnE)
MOXDAMO_1584
AFGAFULGI_00003890
APOArcpr_0184
AVEArcve_0115
ASTAsulf_00150
FPLFerp_1892
GACGACE_1763
GAHGAH_00871
TVOTVG1448112(TVG1448112)
FACFACI_IFERC01G0817
FAIFAD_1708
CDIVCPM_0509
ACJACAM_0191
IHOIgni_1086
IISEYM_01165
IPCIPA_03555
PFMPyrfu_0199
PDLPyrde_1749
PISPisl_1325
PCLPcal_0738
PASPars_0220
PYRP186_2546
POGPogu_2263
TNETneu_0222
PYWPYWP30_00289
CMACmaq_1417
TTNTTX_1950(thiH)
TUZTUZN_1542
VDIVdis_0278
VMOVMUT_1357
NMRNmar_0742
NIRNSED_04040
NKRNKOR_03815
NIDNPIRD3C_1498
NINNADRNF5_1389
NIWNisw_01105
NCLC5F47_05355
NOXC5F49_05220
NUEC5F50_05570
NIPNsoK4_03450
NCTNMSP_0686(cofH_1)
NICDSQ20_05550
CSYCENSYa_1817
NGANgar_c27070(cofH3)
NVNNVIE_015990(cofH2)
NEVNTE_00789
TAANMY3_02629(mqnE_2)
NFNNFRAN_0237(mqnE)
NCVNCAV_1093(mqnE)
NBVT478_0614
TAHSU86_002430
NIUDSQ19_04290
NDVNDEV_1291
CCAINAS2_0521
 » show all
Reference
1  [PMID:24083939]
  Authors
Mahanta N, Fedoseyenko D, Dairi T, Begley TP
  Title
Menaquinone biosynthesis: formation of aminofutalosine requires a unique radical SAM enzyme.
  Journal
J Am Chem Soc 135:15318-21 (2013)
DOI:10.1021/ja408594p
  Sequence
[sco:SCO4494] [ttj:TTHA0804]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.120
IUBMB Enzyme Nomenclature: 2.5.1.120
ExPASy - ENZYME nomenclature database: 2.5.1.120
BRENDA, the Enzyme Database: 2.5.1.120

KEGG   REACTION: R10667
Entry
R10667                      Reaction                               
Name
S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming)
Definition
S-Adenosyl-L-methionine + 3-[(1-Carboxyvinyl)oxy]benzoate + H2O <=> 6-Amino-6-deoxyfutalosine + L-Methionine + HCO3-
Equation
Reaction class
RC00021  C00019_C00073
RC03234  C20772_C20773
Enzyme
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00930  Menaquinone biosynthesis, futalosine pathway
M00931  Menaquinone biosynthesis, modified futalosine pathway
Orthology
K18285  aminodeoxyfutalosine synthase [EC:2.5.1.120]
Other DBs
RHEA: 33078

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