KEGG   ORTHOLOGY: K18395
Entry
K18395            Tight     KO                                     
Symbol
LTMJ
Name
cytochrome P450 monooxygenase [EC:1.14.13.-]
Pathway
map00403  Indole diterpene alkaloid biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00403 Indole diterpene alkaloid biosynthesis
    K18395  LTMJ; cytochrome P450 monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-
     K18395  LTMJ; cytochrome P450 monooxygenase
Other DBs
RN: R10367 R10692 R10694
Genes
AG: AFO85405(LTMJ)
Reference
  Authors
Young CA, Felitti S, Shields K, Spangenberg G, Johnson RD, Bryan GT, Saikia S, Scott B
  Title
A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii.
  Journal
Fungal Genet Biol 43:679-93 (2006)
DOI:10.1016/j.fgb.2006.04.004
Reference
  Authors
Saikia S, Takemoto D, Tapper BA, Lane GA, Fraser K, Scott B
  Title
Functional analysis of an indole-diterpene gene cluster for lolitrem B biosynthesis in the grass endosymbiont Epichloe festucae.
  Journal
FEBS Lett 586:2563-9 (2012)
DOI:10.1016/j.febslet.2012.06.035

KEGG   REACTION: R10367
Entry
R10367                      Reaction                               
Definition
20,21-Diprenylterpendole I + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O
Equation
C20532 + 3 C00007 + 3 C00005 + 3 C00080 <=> C20548 + 3 C00006 + 4 C00001
Comment
cytochrome P450 monooxygenase, LtmJ
Reaction class
RC00001  C00005_C00006
RC03248  C20532_C20548
Enzyme
1.14.13.-
Pathway
rn00403  Indole diterpene alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K18395  cytochrome P450 monooxygenase [EC:1.14.13.-]

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