KEGG   ORTHOLOGY: K18566
Entry
K18566                      KO                                     

Name
thnF, cmmF
Definition
N-acetyltransferase [EC:2.3.1.-]
Pathway
ko00332  Carbapenem biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00332 Carbapenem biosynthesis
    K18566  thnF, cmmF; N-acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.-  
     K18566  thnF, cmmF; N-acetyltransferase
Other DBs
RN: R10745 R10746
COG: COG0456
Genes
SCT: SCAT_p0825(thnF)
SCY: SCATT_p09100
SFA: Sfla_0163
STRP: F750_6858
Reference
  Authors
Freeman MF, Moshos KA, Bodner MJ, Li R, Townsend CA
  Title
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
  Journal
Proc Natl Acad Sci U S A 105:11128-33 (2008)
DOI:10.1073/pnas.0804500105
  Sequence
Reference
  Authors
Li R, Lloyd EP, Moshos KA, Townsend CA
  Title
Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.
  Journal
Chembiochem 15:320-31 (2014)
DOI:10.1002/cbic.201300319

KEGG   REACTION: R10745
Entry
R10745                      Reaction                               

Name
acetyl-CoA:thienamycin N-acetyltransferase
Definition
Acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin
Equation
Reaction class
RC00004  C00010_C00024
RC00096  C06664_C17377
Enzyme
2.3.1.-
Pathway
rn00332  Carbapenem biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K18566  N-acetyltransferase [EC:2.3.1.-]

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