KEGG   ORTHOLOGY: K18568
Entry
K18568                      KO                                     

Name
thnR
Definition
CoA pyrophosphatase [EC:3.6.1.-]
Pathway
ko00332  Carbapenem biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00332 Carbapenem biosynthesis
    K18568  thnR; CoA pyrophosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.-  
     K18568  thnR; CoA pyrophosphatase
Other DBs
RN: R10747
COG: COG0494
GO: 0010945
Genes
SCT: SCAT_p0837(thnR)
SCY: SCATT_p08980
SFA: Sfla_0150
STRP: F750_6871(yeaB)
Reference
  Authors
Freeman MF, Moshos KA, Bodner MJ, Li R, Townsend CA
  Title
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
  Journal
Proc Natl Acad Sci U S A 105:11128-33 (2008)
DOI:10.1073/pnas.0804500105
  Sequence

KEGG   REACTION: R10747
Entry
R10747                      Reaction                               

Name
CoA nucleotidohydrolase
Definition
CoA + H2O <=> Pantetheine 4'-phosphate + Adenosine 3',5'-bisphosphate
Equation
Reaction class
RC00002  C00010_C00054  C00010_C01134
Enzyme
3.6.1.-
Pathway
rn00332  Carbapenem biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K17879  peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-]
K18568  CoA pyrophosphatase [EC:3.6.1.-]
Other DBs
RHEA: 64991

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