KEGG   ORTHOLOGY: K19459
Entry
K19459                      KO                                     

Symbol
LMP1
Name
EBV latent membrane protein 1
Pathway
map05169  Epstein-Barr virus infection
map05203  Viral carcinogenesis
Network
nt06114  PI3K signaling (viruses)
nt06119  JAK-STAT signaling (viruses)
nt06122  IFN signaling (viruses)
nt06123  TNF signaling (viruses and bacteria)
nt06140  Transcription (viruses)
nt06165  Epstein-Barr virus (EBV)
  Element
N00224  EBV EBNALP RBP-Jk-mediated transcription
N00225  EBV EBNA2 to RBP-Jk-mediated transcription
N00226  EBV EBNA3A/3B/3C to RBP-Jk-mediated transcription
N00265  EBV LMP1 to NFKB signaling pathway
N00472  EBV LMP1 to IFN signaling pathway
N00485  EBV LMP1 to PI3K signaling pathway
N00486  EBV LMP1 to Jak-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K19459  LMP1; EBV latent membrane protein 1
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K19459  LMP1; EBV latent membrane protein 1
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19459  LMP1; EBV latent membrane protein 1
Viral proteins [BR:ko03200]
 dsDNA viruses
  Epstein-Barr virus (Human herpesvirus 4)
   K19459  LMP1; EBV latent membrane protein 1
Genes
VG: 2949777(CeHV15gLMP1) 3783750(LMP-1) 5176215(HHV4tp2_gp80)
Reference
PMID:6086953
  Authors
Fennewald S, van Santen V, Kieff E
  Title
Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane protein.
  Journal
J Virol 51:411-9 (1984)
DOI:10.1128/JVI.51.2.411-419.1984
  Sequence
[vg:3783750]
Reference
  Authors
Song YJ, Izumi KM, Shinners NP, Gewurz BE, Kieff E
  Title
IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3.
  Journal
Proc Natl Acad Sci U S A 105:18448-53 (2008)
DOI:10.1073/pnas.0809933105
  Sequence
[vg:3783750]

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