KEGG   ORTHOLOGY: K20594
Entry
K20594            Tight     KO                                     
Symbol
genK, gacD, gntK
Name
cobalamin-dependent radical SAM methyltransferase [EC:2.1.1.-]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20594  genK, gacD, gntK; cobalamin-dependent radical SAM methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     K20594  genK, gacD, gntK; cobalamin-dependent radical SAM methyltransferase
Other DBs
RN: R11294
COG: COG1032
Genes
AG: CAF31440(genK)
Reference
  Authors
Kim HJ, McCarty RM, Ogasawara Y, Liu YN, Mansoorabadi SO, LeVieux J, Liu HW
  Title
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
  Journal
J Am Chem Soc 135:8093-6 (2013)
DOI:10.1021/ja312641f
  Sequence

DBGET integrated database retrieval system