KEGG   ORTHOLOGY: K20594
Entry
K20594            Tight     KO                                     
Symbol
genK, gacD, gntK
Name
cobalamin-dependent radical SAM methyltransferase [EC:2.1.1.-]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20594  genK, gacD, gntK; cobalamin-dependent radical SAM methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     K20594  genK, gacD, gntK; cobalamin-dependent radical SAM methyltransferase
Other DBs
RN: R11294
COG: COG1032
Genes
AG: CAF31440(genK)
Reference
PMID:23679096
  Authors
Kim HJ, McCarty RM, Ogasawara Y, Liu YN, Mansoorabadi SO, LeVieux J, Liu HW
  Title
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
  Journal
J Am Chem Soc 135:8093-6 (2013)
DOI:10.1021/ja312641f
  Sequence
[ag:CAF31440]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (1)   
   PubMed (1)   
All databases (11)   

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