KEGG   ORTHOLOGY: K20681
Entry
K20681            Tight     KO                                     
Symbol
fdtC
Name
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
Pathway
map00523  Polyketide sugar unit biosynthesis
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K20681  fdtC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K20681  fdtC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.197  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
     K20681  fdtC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Other DBs
RN: R09873
COG: COG1207
Genes
AG: AAS55721(fdtC)
Reference
PMID:12740380
  Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
  Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200
  Sequence
[ag:AAS55721]

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Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1)   
   KEGG GENES (1)   
Literature (1)   
   PubMed (1)   
All databases (19)   

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KEGG   ENZYME: 2.3.1.197
Entry
EC 2.3.1.197                Enzyme                                 
Name
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase;
FdtC;
dTDP-D-Fucp3N acetylase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose = CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [RN:R09873]
Reaction(KEGG)
R09873
Substrate
acetyl-CoA [CPD:C00024];
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose [CPD:C19947]
Product
CoA [CPD:C00010];
dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [CPD:C20156]
Comment
The product, dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose, is a component of the glycan chain of the crystalline bacterial cell surface layer protein (S-layer glycoprotein) of Aneurinibacillus thermoaerophilus.
History
EC 2.3.1.197 created 2012
Pathway
ec00523  Polyketide sugar unit biosynthesis
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Reference
1  [PMID:12740380]
  Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
  Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200
  Sequence
[ag:AAS55721]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.197
IUBMB Enzyme Nomenclature: 2.3.1.197
ExPASy - ENZYME nomenclature database: 2.3.1.197
BRENDA, the Enzyme Database: 2.3.1.197

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Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (212)   
   UniProt (210)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (254)   
   RefSeq(nuc) (1)   
   GenBank (127)   
   EMBL (126)   
Protein domain (2)   
   InterPro (2)   
All databases (485)   

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KEGG   REACTION: R09873
Entry
R09873                      Reaction                               
Name
acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Definition
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose
Equation
C00024 + C19947 <=> C00010 + C20156
Reaction class
RC00004  C00010_C00024
RC00166  C19947_C20156
Enzyme
2.3.1.197
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Orthology
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
Other DBs
RHEA: 32098

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (20)   

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