KEGG   ORTHOLOGY: K21206
Entry
K21206            Tight     KO                                     

Symbol
CYP82D61
Name
(-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase [EC:1.14.14.132]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K21206  CYP82D61; (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.132  (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
     K21206  CYP82D61; (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP82 family
   K21206  CYP82D61; (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
Genes
AG: ALG05144(CYP82D61)
Reference
  Authors
Lau W, Sattely ES
  Title
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.
  Journal
Science 349:1224-8 (2015)
DOI:10.1126/science.aac7202
  Sequence

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