KEGG   ORTHOLOGY: K21224
Entry
K21224                      KO                                     
Symbol
kedN5
Name
radical SAM C-methyltransferase
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00831  Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21224  kedN5; radical SAM C-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21224  kedN5; radical SAM C-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K21224  kedN5; radical SAM C-methyltransferase
Other DBs
RN: R11389
COG: COG1032
Genes
SGR: SGR_913
SROI: IAG44_01145
SACC: EYD13_10955(rimO1)
SESP: BN6_45930
KPHY: AOZ06_30985
AHM: TL08_15140
ALO: CRK61978
SAQ: Sare_2941
MAU: Micau_3868
MIL: ML5_4549
MTUA: CSH63_06280
AG: AFV52163(kedN5)
 » show all
Reference
PMID:23360970
  Authors
Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B
  Title
Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.
  Journal
Mol Biosyst 9:478-91 (2013)
DOI:10.1039/c3mb25523a
  Sequence
[ag:AFV52163]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (18)   
   KEGG GENES (12)   
   RefGene (5)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (31)   

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