KEGG   ORTHOLOGY: K21224
Entry
K21224                      KO                                     
Symbol
kedN5
Name
radical SAM C-methyltransferase
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00831  Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21224  kedN5; radical SAM C-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21224  kedN5; radical SAM C-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K21224  kedN5; radical SAM C-methyltransferase
Other DBs
RN: R11389
COG: COG1032
Genes
SGR: SGR_913
SROI: IAG44_01145
SACC: EYD13_10955(rimO1)
SESP: BN6_45930
KPHY: AOZ06_30985
AHM: TL08_15140
ALO: CRK61978
SAQ: Sare_2941
MAU: Micau_3868
MIL: ML5_4549
AG: AFV52163(kedN5)
 » show all
Reference
  Authors
Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B
  Title
Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.
  Journal
Mol Biosyst 9:478-91 (2013)
DOI:10.1039/c3mb25523a
  Sequence

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