KEGG   ORTHOLOGY: K21278
Entry
K21278                      KO                                     
Symbol
DUSP1
Name
dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
Pathway
map04010  MAPK signaling pathway
map04726  Serotonergic synapse
map05012  Parkinson disease
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K21278  DUSP1; dual specificity protein phosphatase 1
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K21278  DUSP1; dual specificity protein phosphatase 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K21278  DUSP1; dual specificity protein phosphatase 1
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K21278  DUSP1; dual specificity protein phosphatase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K21278  DUSP1; dual specificity protein phosphatase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K21278  DUSP1; dual specificity protein phosphatase 1
    3.1.3.48  protein-tyrosine-phosphatase
     K21278  DUSP1; dual specificity protein phosphatase 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    K21278  DUSP1; dual specificity protein phosphatase 1
Other DBs
GO: 0017017 0004725
Genes
HSA: 1843(DUSP1)
PTR: 471742(DUSP1)
PPS: 100978783(DUSP1)
GGO: 101145560(DUSP1)
PON: 100435862(DUSP1)
NLE: 100591464(DUSP1)
MCC: 702981(DUSP1)
MCF: 102116284(DUSP1)
MTHB: 126956345
CSAB: 103244980(DUSP1)
CATY: 105581659(DUSP1)
PANU: 100997568(DUSP1)
TGE: 112625873(DUSP1)
RRO: 104670131(DUSP1)
RBB: 108520017(DUSP1)
TFN: 117065462(DUSP1)
PTEH: 111547221(DUSP1)
CJC: 100393730(DUSP1)
SBQ: 101043469(DUSP1)
CSYR: 103252868(DUSP1)
MMUR: 105871862(DUSP1)
LCAT: 123637948(DUSP1)
OGA: 100945193(DUSP1)
MMU: 19252(Dusp1)
MCAL: 110312644(Dusp1)
MPAH: 110337954(Dusp1)
RNO: 114856(Dusp1)
MCOC: 116078286(Dusp1)
MUN: 110547818(Dusp1)
CGE: 100769474(Dusp1)
MAUA: 101831197(Dusp1)
PLEU: 114709487(Dusp1)
MORG: 121464047(Dusp1)
MFOT: 126498056
AAMP: 119812340(Dusp1)
NGI: 103748194(Dusp1)
HGL: 101701425(Dusp1)
CPOC: 100725668(Dusp1)
CCAN: 109694781(Dusp1)
DORD: 105985414(Dusp1)
DSP: 122099537(Dusp1)
NCAR: 124987585
OCU: 100340993
OPI: 101531665(DUSP1)
TUP: 102481474(DUSP1)
GVR: 103595912(DUSP1)
CFA: 489117(DUSP1)
CLUD: 112651454(DUSP1)
VVP: 112926138(DUSP1)
VLG: 121488137(DUSP1)
AML: 100483084(DUSP1)
UMR: 103664491(DUSP1)
UAH: 113264095(DUSP1)
UAR: 123788597(DUSP1)
ELK: 111140958
LLV: 125100671
MPUF: 101693585(DUSP1)
ORO: 101376261(DUSP1)
EJU: 114208648(DUSP1)
ZCA: 113929802(DUSP1)
MLX: 118016761(DUSP1)
NSU: 110588080(DUSP1)
LWW: 102740993(DUSP1)
FCA: 101093416(DUSP1)
PYU: 121011080(DUSP1)
PBG: 122492214(DUSP1)
LRUF: 124520324
PTG: 102960774(DUSP1)
PPAD: 109267510(DUSP1)
AJU: 106975373(DUSP1)
HHV: 120234102(DUSP1)
BTA: 539175(DUSP1)
BOM: 102266766(DUSP1)
BIU: 109574921(DUSP1)
BBUB: 102410828(DUSP1)
BBIS: 104996902(DUSP1)
CHX: 102180080(DUSP1)
OAS: 101107632(DUSP1)
ODA: 120879670(DUSP1)
CCAD: 122454393(DUSP1)
SSC: 100522469(DUSP1)
CFR: 102505108(DUSP1)
CBAI: 105082649(DUSP1)
CDK: 105089401(DUSP1)
VPC: 102538892(DUSP1)
BACU: 103004641(DUSP1)
LVE: 103073987(DUSP1)
OOR: 101278083(DUSP1)
DLE: 111185473(DUSP1)
PCAD: 102994142(DUSP1)
PSIU: 116751751(DUSP1)
ECB: 100069834(DUSP1)
EPZ: 103542920(DUSP1)
EAI: 106837352(DUSP1)
MYB: 102264079(DUSP1)
MYD: 102760550(DUSP1)
MMYO: 118658302(DUSP1)
MLF: 102434907(DUSP1)
MNA: 107535716(DUSP1)
PKL: 118711557(DUSP1)
HAI: 109379363(DUSP1)
DRO: 112319677(DUSP1)
SHON: 118994956(DUSP1)
AJM: 119036235(DUSP1)
PDIC: 114510076(DUSP1)
PHAS: 123813204(DUSP1)
MMF: 118615867(DUSP1)
RFQ: 117016981(DUSP1)
PALE: 102894546(DUSP1)
PGIG: 120615021(DUSP1)
PVP: 105299303(DUSP1)
RAY: 107511030(DUSP1)
MJV: 108398732(DUSP1)
TOD: 119235228(DUSP1)
SARA: 101553959(DUSP1)
LAV: 100665180(DUSP1)
TMU: 101352955
ETF: 101661665(DUSP1)
DNM: 101426146(DUSP1)
MDO: 100031265(DUSP1)
GAS: 123237492(DUSP1)
SHR: 100923908(DUSP1)
PCW: 110196069(DUSP1)
OAA: 100076090(DUSP1)
GGA: 374192(DUSP1)
PCOC: 116232035(DUSP1)
MGP: 100546569(DUSP1)
CJO: 107320475(DUSP1)
NMEL: 110405394(DUSP1)
APLA: 101802393(DUSP1)
ACYG: 106042748(DUSP1)
AFUL: 116495021(DUSP1)
TGU: 100219518(DUSP1)
LSR: 110471461(DUSP1)
SCAN: 103824102(DUSP1)
PMOA: 120498639(DUSP1)
OTC: 121332379(DUSP1)
PRUF: 121365634(DUSP1)
GFR: 102033656(DUSP1)
FAB: 101821078(DUSP1)
PHI: 102114546(DUSP1)
PMAJ: 107210905(DUSP1)
CCAE: 111935377(DUSP1)
CCW: 104689650(DUSP1)
CBRC: 103611569(DUSP1)
ETL: 114066568(DUSP1)
ZAB: 102068767(DUSP1)
ACHL: 103803993(DUSP1)
FPG: 101917721(DUSP1)
FCH: 102053987(DUSP1)
CLV: 102089263(DUSP1)
EGZ: 104133636(DUSP1)
NNI: 104018968(DUSP1)
PLET: 104627753(DUSP1)
PCRI: 104027404(DUSP1)
PCAO: 104045232(DUSP1)
ACUN: 113485411(DUSP1)
TALA: 104363136(DUSP1)
PADL: 103912304(DUSP1)
AFOR: 103904504(DUSP1)
ACHC: 115334328(DUSP1)
HALD: 104320040(DUSP1)
HLE: 104838995(DUSP1)
AGEN: 126050842
GCL: 127022068
CSTI: 104559941(DUSP1)
CMAC: 104485259(DUSP1)
MUI: 104537598(DUSP1)
GSTE: 104259287(DUSP1)
LDI: 104351976(DUSP1)
MNB: 103778990(DUSP1)
OHA: 104332214(DUSP1)
NNT: 104411934(DUSP1)
DPUB: 104303946(DUSP1)
PGUU: 104469727(DUSP1)
ACAR: 104530417
CPEA: 104392648(DUSP1)
AVIT: 104280282(DUSP1)
CVF: 104283862(DUSP1)
CUCA: 104065581(DUSP1)
TEO: 104381646(DUSP1)
BRHI: 104496350(DUSP1)
AAM: 106497521(DUSP1)
AROW: 112964735(DUSP1)
NPD: 112954502(DUSP1)
TGT: 104572807
DNE: 112996968(DUSP1)
SCAM: 104142462(DUSP1)
ASN: 102375445(DUSP1)
AMJ: 102559641(DUSP1)
CPOO: 109310009(DUSP1)
GGN: 109290041(DUSP1)
PSS: 102463448(DUSP1)
CMY: 102948279(DUSP1)
CPIC: 101936270(DUSP1)
TST: 117881879(DUSP1)
CABI: 116837244(DUSP1)
MRV: 120370112(DUSP1)
ACS: 100557150(dusp1)
PVT: 110086132(DUSP1)
SUND: 121923180(DUSP1)
PBI: 103061052(DUSP1)
PMUR: 107294676(DUSP1)
CTIG: 120311985(DUSP1)
TSR: 106540028(DUSP1)
PGUT: 117657042 117657383(DUSP1)
VKO: 123035828(DUSP1)
PMUA: 114591047(DUSP1)
ZVI: 118080296(DUSP1)
GJA: 107124748(DUSP1)
STOW: 125429842(DUSP1)
XLA: 380262(dusp1.L) 398254(dusp1.S)
XTR: 448043(dusp1)
NPR: 108788764(DUSP1)
RTEM: 120932271(DUSP1)
BBUF: 120978125(DUSP1)
BGAR: 122928163(DUSP1)
DRE: 406340(dusp1)
PPRM: 120464368(dusp1)
MAMB: 125259015(dusp1)
IPU: 108268678(dusp1)
PHYP: 113542903(dusp1)
SMEO: 124386498(dusp1)
TFD: 113647798(dusp1)
AMEX: 103038437(dusp1)
EEE: 113576529
TRU: 101074284(dusp1)
LCO: 104936101(dusp1)
NCC: 104959297(dusp1)
CGOB: 115014913(dusp1)
ELY: 117261229(dusp1)
EFO: 125894304(dusp1)
PLEP: 121948033(dusp1)
SLUC: 116064228(dusp1)
ECRA: 117951932(dusp1)
ESP: 116697230(dusp1)
PFLV: 114562612(dusp1)
GAT: 120818003(dusp1)
PPUG: 119211338(dusp1)
MSAM: 119889382(dusp1)
CUD: 121516018(dusp1)
ALAT: 119007720(dusp1)
MZE: 101487702(dusp1)
ONL: 100694058(dusp1)
OAU: 116324554(dusp1)
OLA: 101173794(dusp1)
OML: 112153347(dusp1)
XMA: 102232508(dusp1)
XCO: 114139363(dusp1)
XHE: 116714079(dusp1)
PRET: 103471107(dusp1)
PFOR: 103144546(dusp1)
PLAI: 106947098(dusp1)
PMEI: 106929685(dusp1)
GAF: 122837415(dusp1)
CVG: 107093461(dusp1)
CTUL: 119783207(dusp1)
GMU: 124859767(dusp1)
NFU: 107394133(dusp1)
KMR: 108242066(dusp1)
ALIM: 106510863(dusp1)
NWH: 119409059(dusp1)
AOCE: 111578781(dusp1)
MCEP: 125008164(dusp1)
CSEM: 103391114(dusp1)
POV: 109647322(dusp1)
SSEN: 122778966(dusp1)
HHIP: 117768814(dusp1)
HSP: 118112328(dusp1)
LCF: 108882864
SDU: 111226686(dusp1)
SLAL: 111652061(dusp1)
XGL: 120785624(dusp1)
HCQ: 109515925(dusp1)
BPEC: 110163462(dusp1)
MALB: 109968408(dusp1)
BSPL: 114864794(dusp1)
OTW: 112241347 112241498(dusp1)
OMY: 110487960 110504465(dusp1)
OGO: 123994218(dusp1) 124011447
ONE: 115123656(dusp1)
SNH: 120047837 120062585(dusp1)
ELS: 105026777(dusp1)
SFM: 108931840(dusp1)
PKI: 111857699(dusp1)
AANG: 118224188(dusp1)
LOC: 102688449(dusp1)
PSEX: 120542340(dusp1)
LCM: 102364866(DUSP1)
CMK: 103190804(dusp1)
RTP: 109914245(dusp1) 109924522
BFO: 118413453
BBEL: 109485283
CIN: 778913(dusp1.2.4.5)
SKO: 100369648
PTRU: 123510318
VDE: 111255027
VJA: 111268975
PCAN: 112564659
BGT: 106050206
GAE: 121383351
HRF: 124149166
CRG: 105344429
MYI: 110447324
PMAX: 117339294
OSN: 115219997
EGL: EGR_07162
NVE: 5521409
EPA: 110238003
ATEN: 116299033
ADF: 107337768
AMIL: 114965681
PDAM: 113680105
SPIS: 111335069
 » show all
Reference
PMID:1406996
  Authors
Keyse SM, Emslie EA
  Title
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase.
  Journal
Nature 359:644-7 (1992)
DOI:10.1038/359644a0
  Sequence
[hsa:1843]

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