KEGG   ORTHOLOGY: K21325
Entry
K21325                      KO                                     
Symbol
calS11
Name
dTDP-rhamnose C3-O-methyltransferase [EC:2.1.1.-]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K21325  calS11; dTDP-rhamnose C3-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     K21325  calS11; dTDP-rhamnose C3-O-methyltransferase
Other DBs
RN: R11469
Genes
STP: Strop_2056
SAQ: Sare_2046
AG: AAM70337(calS11)
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN Jr, Thorson JS
  Title
Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis.
  Journal
ACS Chem Biol 8:1632-9 (2013)
DOI:10.1021/cb400068k

KEGG   REACTION: R11469
Entry
R11469                      Reaction                               
Name
S-adenosyl-L-methionine:dTDP-L-rhamnose 3'-O-methyltransferase
Definition
S-Adenosyl-L-methionine + dTDP-L-rhamnose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-beta-L-rhamnose
Equation
Reaction class
RC00466  C03319_C21350
Enzyme
2.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K21325  dTDP-rhamnose C3-O-methyltransferase [EC:2.1.1.-]

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