KEGG   ORTHOLOGY: K21398
Entry
K21398                      KO                                     

Symbol
SLC11A2, DMT1, NRAMP2
Name
natural resistance-associated macrophage protein 2
Pathway
map04142  Lysosome
map04216  Ferroptosis
map04978  Mineral absorption
map05010  Alzheimer disease
map05012  Parkinson disease
Disease
H01196  Hypochromic microcytic anemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
  09143 Cell growth and death
   04216 Ferroptosis
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
   05012 Parkinson disease
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC11: Proton-coupled metal ion transporter
   K21398  SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
Other DBs
GO: 0005375 0005384 0005385 0015086 0015087 0015093 0015094 0015099 0015100
TC: 2.A.55.2.1 2.A.55.2.2
Genes
HSA: 4891(SLC11A2)
PTR: 451897(SLC11A2)
PPS: 100985494(SLC11A2)
GGO: 101136937(SLC11A2)
PON: 100434194(SLC11A2)
NLE: 100587635(SLC11A2)
MCC: 693986(SLC11A2)
MCF: 101865397(SLC11A2)
CSAB: 103238312(SLC11A2)
CATY: 105580347(SLC11A2)
PANU: 101014799(SLC11A2)
RRO: 104679680(SLC11A2)
RBB: 108521603(SLC11A2)
TFN: 117090124(SLC11A2)
PTEH: 111542001(SLC11A2)
CJC: 100399071 100403822(SLC11A2)
SBQ: 101034061(SLC11A2)
MMUR: 105870047
MMU: 18174(Slc11a2)
MCAL: 110310195(Slc11a2)
MPAH: 110334498(Slc11a2)
RNO: 25715(Slc11a2)
MCOC: 116079784(Slc11a2)
MUN: 110561547(Slc11a2)
CGE: 100764508(Slc11a2)
PLEU: 114696672(Slc11a2)
NGI: 103730627(Slc11a2)
HGL: 101723788(Slc11a2)
CPOC: 100718794
CCAN: 109696737
OCU: 100342532(SLC11A2)
OPI: 101529528(SLC11A2)
TUP: 102472123(SLC11A2)
CFA: 486543(SLC11A2)
VVP: 112921138(SLC11A2)
VLG: 121480002(SLC11A2)
AML: 100479673(SLC11A2)
UMR: 103675484(SLC11A2)
UAH: 113257616(SLC11A2)
ORO: 101381263(SLC11A2)
ELK: 111157824
MPUF: 101691433(SLC11A2)
EJU: 114225792(SLC11A2)
MLX: 118008847(SLC11A2)
FCA: 101089199(SLC11A2)
PYU: 121038575(SLC11A2)
PBG: 122473395(SLC11A2)
PTG: 102965906(SLC11A2)
PPAD: 109249112(SLC11A2)
AJU: 106969220(SLC11A2)
HHV: 120237890(SLC11A2)
BTA: 112441543 512464 521189(SLC11A2)
BBUB: 102405734(SLC11A2) 102407231
CHX: 102190297(SLC11A2) 102190935
SSC: 733595(SLC11A2)
CFR: 102515134(SLC11A2)
CBAI: 105076232(SLC11A2)
CDK: 105107145(SLC11A2)
BACU: 103011734(SLC11A2)
LVE: 103068514(SLC11A2)
OOR: 101279475(SLC11A2)
DLE: 111174003(SLC11A2)
PCAD: 102989308(SLC11A2)
PSIU: 116760797(SLC11A2)
ECB: 100052385(SLC11A2)
EPZ: 103545846(SLC11A2)
EAI: 106835221(SLC11A2)
MYB: 102252488(SLC11A2)
MYD: 102771606(SLC11A2)
MMYO: 118649602(SLC11A2)
MLF: 102426506(SLC11A2)
MNA: 107528272(SLC11A2)
PKL: 118730148(SLC11A2)
HAI: 109371397(SLC11A2)
DRO: 112318244(SLC11A2)
SHON: 118976391(SLC11A2)
AJM: 119038722 119042978(SLC11A2)
PDIC: 114513495(SLC11A2)
MMF: 118623447(SLC11A2)
RFQ: 117028241(SLC11A2)
PALE: 102888126(SLC11A2)
PGIG: 120602147(SLC11A2)
RAY: 107509802(SLC11A2)
MJV: 108401554(SLC11A2)
TOD: 119247918(SLC11A2)
LAV: 100661689(SLC11A2)
TMU: 101340601
MDO: 100023292(SLC11A2)
GAS: 123230469 123249601(SLC11A2)
SHR: 100927191(SLC11A2)
PCW: 110194012(SLC11A2)
OAA: 100090781(SLC11A2)
GGA: 751817(SLC11A2)
CJO: 107325802(SLC11A2)
APLA: 101793552(SLC11A2)
ACYG: 106048713(SLC11A2)
TGU: 115491394
SCAN: 103825258
PMOA: 120499468
OTC: 121334296
PRUF: 121356361(SLC11A2)
GFR: 102034086
FAB: 101810585(SLC11A2)
PHI: 102102844(SLC11A2)
PMAJ: 107199188
CCAE: 111940458(SLC11A2)
ETL: 114071818
FPG: 101915138(SLC11A2)
FCH: 102046218(SLC11A2)
EGZ: 104127753(SLC11A2)
NNI: 104019186(SLC11A2)
ACUN: 113490968
PADL: 103914313(SLC11A2)
AAM: 106485343
AROW: 112972131(SLC11A2)
NPD: 112952246(SLC11A2)
DNE: 112991458(SLC11A2)
ASN: 102388285(SLC11A2)
AMJ: 102575517(SLC11A2)
PSS: 102452842(SLC11A2)
CMY: 102944546(SLC11A2)
CPIC: 101953240(SLC11A2)
TST: 117889286(SLC11A2)
CABI: 116828533(SLC11A2)
MRV: 120391040(SLC11A2)
ACS: 100560898(slc11a2)
PVT: 110074391(SLC11A2)
SUND: 121921131(SLC11A2)
PBI: 103052874(SLC11A2)
PMUR: 107291517(SLC11A2)
TSR: 106546106(SLC11A2)
PGUT: 117662688(SLC11A2)
VKO: 123029901(SLC11A2)
PMUA: 114593023(SLC11A2)
ZVI: 118079054(SLC11A2)
GJA: 107118395(SLC11A2)
XLA: 108708604(slc11a2.L) 108708997(slc11a2.S)
XTR: 100144712(slc11a2)
NPR: 108791586(SLC11A2)
DRE: 678623(slc11a2)
SRX: 107747835
SGH: 107561796
CCAR: 109070414
IPU: 100304514
AMEX: 103037062
EEE: 113572426
LCO: 104937242
NCC: 104954751(slc11a2)
PPUG: 119193943(slc11a2) 119222307
OAU: 116309203 116329892(slc11a2)
GAF: 122833794(slc11a2) 122835529
NFU: 107385674(slc11a2)
KMR: 108235664(slc11a2)
ALIM: 106533487(slc11a2)
OMY: 100135867(nramp-alpha) 100135868(nramp-beta) 110492017
AANG: 118208182 118210585(slc11a2)
LOC: 102685311(slc11a2)
PSPA: 121308961(slc11a2)
LCM: 102354576(SLC11A2)
CMK: 103191366
RTP: 109911483
SKO: 100378874
DME: Dmel_CG3671(Mvl)
DER: 6553517
DSE: 6620068
DSI: Dsimw501_GD20014(Dsim_Mvl)
DYA: Dyak_GE25020(Dyak_Mvl)
DAN: 6501296
DSR: 110190139
DPE: 6594357
DMN: 108156840
DWI: 6650319
DGR: 6567772
DAZ: 108621372
DNV: 108659627
DHE: 111596437
DVI: 6632868
CCAT: 101449204
BOD: 106617080
MDE: 101889828
SCAC: 106092907
LCQ: 111684771
ACOZ: 120955073
AARA: 120901741
AME: 494509
ACER: 108000661
BIM: 100747233
BBIF: 117206283
BVK: 117243198
BVAN: 117155426
BTER: 100642226
BPYO: 122575227
CCAL: 108627698
OBB: 114876340
MGEN: 117226442
NMEA: 116432768
CGIG: 122400931
SOC: 105194195
MPHA: 105840451
AEC: 105143223
ACEP: 105627549
PBAR: 105427181
VEM: 105563242
HST: 105189561
DQU: 106747860
CFO: 105254494
FEX: 115239909
LHU: 105677051
PGC: 109862085
OBO: 105274956
PCF: 106793091
PFUC: 122517017
VPS: 122628896
NVI: 100116484
CSOL: 105366640
MDL: 103576937
CGLO: 123269159
FAS: 105272016
DAM: 107040928
CCIN: 107275034
LDC: 111507490
DNX: 107167604
RMD: 113551438
BTAB: 109032455
DCI: 103506700
ZNE: 110837408
CSEC: 111868901
FCD: 110852674
DPX: DAPPUDRAFT_347258(MVL1)
PVM: 113810232
HAME: 121866188
HAZT: 108682466
DSV: 119442730
RMP: 119188239
VDE: 111244283
VJA: 111263974
TUT: 107365956
CSCU: 111621304
PTEP: 107445388
CEL: CELE_K11G12.3(smf-2) CELE_K11G12.4(smf-1) CELE_Y69A2AR.4(smf-3)
CBR: CBG_10874(Cbr-smf-2) CBG_10875(Cbr-smf-1) CBG_13883(Cbr-smf-3)
BMY: BM_BM13827(Bm13827)
BGT: 106069981
NVE: 5515499
EPA: 110254631
ATEN: 116306781
ADF: 107330888
AMIL: 114955276
PDAM: 113682799
HMG: 100212794
ATH: AT1G15960(NRAMP6) AT1G47240(NRAMP2) AT1G80830(NRAMP1) AT2G23150(NRAMP3) AT4G18790(NRAMP5) AT5G67330(NRAMP4)
GMX: 100787785(NRAMP7) 100789871(NRAMP1B) 100791117(NRAMP3A) 100795013(NRAMP3B) 100797298(NRAMP6A) 100800523(NRAMP5B) 100801411(NRAMP4A) 100803732(NRAMP4B) 100807811(NRAMP1A) 100808501(NRAMP6B) 100812381(NRAMP2A) 100815628(NRAMP5A) 547711(DMT1)
LJA: Lj0g3v0120889.1(Lj0g3v0120889.1) Lj0g3v0158689.2(Lj0g3v0158689.2) Lj1g3v0862950.1(Lj1g3v0862950.1) Lj1g3v1698940.2(Lj1g3v1698940.2) Lj2g3v1925820.1(Lj2g3v1925820.1) Lj4g3v0793350.1(Lj4g3v0793350.1) Lj4g3v1500410.2(Lj4g3v1500410.2) Lj6g3v2258850.1(Lj6g3v2258850.1)
SLY: 101246519 543868(NRAMP1) 543927(LeNramp2) 544257(NRAMP3)
DOSA: Os02t0131800-01(Os02g0131800) Os03t0208500-01(Os03g0208500) Os06t0676000-01(Os06g0676000) Os07t0257200-01(Os07g0257200) Os07t0258400-01(Os07g0258400) Os12t0581600-01(Os12g0581600)
OLU: OSTLU_27409(NRAMP1)
DDI: DDB_G0276973(nramp1)
DFA: DFA_03314(nramp1)
PCB: PCHAS_123900(PC000265.01.0)
SPAR: SPRG_04695
 » show all
Reference
  Authors
Mackenzie B, Takanaga H, Hubert N, Rolfs A, Hediger MA
  Title
Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1).
  Journal
Biochem J 403:59-69 (2007)
DOI:10.1042/BJ20061290
  Sequence
[hsa:4891]

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