KEGG   ORTHOLOGY: K22326
Entry
K22326            Tight     KO                                     

Name
CYP5437
Definition
vinorine hydroxylase [EC:1.14.14.104]
Pathway
ko00901  Indole alkaloid biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K22326  CYP5437; vinorine hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.104  vinorine hydroxylase
     K22326  CYP5437; vinorine hydroxylase
Other DBs
RN: R05877
GO: 0050596
Genes
AG: ASG81458(CYP5437)
Reference
  Authors
Dang TT, Franke J, Tatsis E, O'Connor SE
  Title
Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina.
  Journal
Angew Chem Int Ed Engl 56:9440-9444 (2017)
DOI:10.1002/anie.201705010
  Sequence

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