KEGG   ORTHOLOGY: K24034
Entry
K24034                      KO                                     

Symbol
SPE3-LYS9
Name
spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10]
Pathway
map00270  Cysteine and methionine metabolism
map00300  Lysine biosynthesis
map00310  Lysine degradation
map00330  Arginine and proline metabolism
map00480  Glutathione metabolism
map01100  Metabolic pathways
map01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00300 Lysine biosynthesis
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00310 Lysine degradation
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
   00330 Arginine and proline metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.10  saccharopine dehydrogenase (NADP+, L-glutamate-forming)
     K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.16  spermidine synthase
     K24034  SPE3-LYS9; spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming)
Other DBs
RN: R01920 R02315 R08359
COG: COG0421 COG1748
GO: 0004766 0004755
Genes
CNE: CNG01150
CNB: CNBG3640
CGI: CGB_G5220C
TMS: TREMEDRAFT_74272
TASA: A1Q1_06672
TVS: TRAVEDRAFT_53623
DSQ: DICSQDRAFT_85486
PCO: PHACADRAFT_187523 PHACADRAFT_262714
SHS: STEHIDRAFT_76391
HIR: HETIRDRAFT_471805
ABP: AGABI1DRAFT64147(AGABI1DRAFT_64147)
ABV: AGABI2DRAFT184364(AGABI2DRAFT_184364)
MGL: MGL_1529
MRT: MRET_3829
 » show all
Reference
  Authors
Kingsbury JM, Yang Z, Ganous TM, Cox GM, McCusker JH
  Title
Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans.
  Journal
Eukaryot Cell 3:752-63 (2004)
DOI:10.1128/EC.3.3.752-763.2004
  Sequence
[cne:CNG01150]

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