KEGG   ORTHOLOGY: K24304
Entry
K24304                      KO                                     
Symbol
lea5
Name
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase
Pathway
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K24304  lea5; UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase
Other DBs
RN: R12558
COG: COG0381
Genes
VVU: VV1_0807
VVM: VVMO6_02803
VHA: VIBHAR_00671
VCA: M892_09495
SSEI: FJR45_00980(neuC)
DBK: DGMP_13520
BBAE: FRD01_15940(neuC)
THAI: IT893_15830(neuC)
TEB: T8CH_0144(legG)
EMAI: KZP23_21775(neuC)
PPEC: H9W90_01220(neuC)
AG: ADJ19197(lea5)
 » show all
Reference
  Authors
Li X, Perepelov AV, Wang Q, Senchenkova SN, Liu B, Shevelev SD, Guo X, Shashkov AS, Chen W, Wang L, Knirel YA
  Title
Structural and genetic characterization of the O-antigen of Escherichia coli O161 containing a derivative of a higher acidic diamino sugar, legionaminic acid.
  Journal
Carbohydr Res 345:1581-7 (2010)
DOI:10.1016/j.carres.2010.04.008
  Sequence
Reference
  Authors
McDonald ND, DeMeester KE, Lewis AL, Grimes CL, Boyd EF
  Title
Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide.
  Journal
J Biol Chem 293:19113-19126 (2018)
DOI:10.1074/jbc.RA118.004966

KEGG   REACTION: R12558
Entry
R12558                      Reaction                               
Definition
UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose
Equation
Comment
2-epimerase
Reaction class
RC00290  C22247_C22248
Enzyme
5.1.3.-
Pathway
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Orthology
K24304  UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucose 2-epimerase

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