KEGG   MODULE: M00884
Entry
M00884            Pathway   Module                                 
Name
Lipoic acid biosynthesis, octanoyl-CoA => dihydrolipoyl-E2
Definition
K23750 K03644
Diagram
M00884

Orthology
K23750  
LIP3; octanoyl-CoA:protein transferase [EC:2.3.1.-] [RN:R12431]
K03644  
LIP5; lipoyl synthase [EC:2.8.1.8] [RN:R12423]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00785  Lipoic acid metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
Compound
C01944  Octanoyl-CoA
C22160  [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine
C15973  [Lipoyl-carrier protein E2]-N6-[(R)-dihydrolipoyl]-L-lysine
Reference
  Authors
Hermes FA, Cronan JE
  Title
The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis.
  Journal
Yeast 30:415-27 (2013)
DOI:10.1002/yea.2979

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