KEGG   MODULE: M00891
Entry
M00891            Pathway   Module                                 
Name
Ditryptophenaline biosynthesis, tryptophan + phenylalanine => ditryptophenaline
Definition
K23646 K23647 K21477
Diagram
M00891

Orthology
K23646  
DTPA; ditryptophenaline biosynthesis nonribosomal peptide synthase [EC:6.3.2.-] [RN:R12413]
K23647  
DTPB; ditryptophenaline biosynthesis N-methyltransferase [EC:2.1.1.-] [RN:R12414]
K21477  
DTPC; ditryptophenaline biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-] [RN:R12415]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other fungal compounds
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R12413  
R12414  
R12415  
Compound
C00078  L-Tryptophan
C00079  L-Phenylalanine
C22142  Cyclo(L-Trp-L-Phe)
C22143  N-Methyl-cyclo(L-Trp-L-Phe)
C22144  (-)-Ditryptophenaline
Reference
PMID:24677498
  Authors
Saruwatari T, Yagishita F, Mino T, Noguchi H, Hotta K, Watanabe K
  Title
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis.
  Journal
Chembiochem 15:656-9 (2014)
DOI:10.1002/cbic.201300751

  All links  
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG REACTION (3)   
Gene (3)   
   KEGG ORTHOLOGY (3)   
Literature (1)   
   PubMed (1)   
All databases (15)   

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