KEGG   MODULE: M00891
Entry
M00891            Pathway   Module                                 
Name
Ditryptophenaline biosynthesis, tryptophan + phenylalanine => ditryptophenaline
Definition
K23646 K23647 K21477
Diagram
M00891

Orthology
K23646  
DTPA; ditryptophenaline biosynthesis nonribosomal peptide synthase [EC:6.3.2.-] [RN:R12413]
K23647  
DTPB; ditryptophenaline biosynthesis N-methyltransferase [EC:2.1.1.-] [RN:R12414]
K21477  
DTPC; ditryptophenaline biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-] [RN:R12415]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other fungal compounds
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C00078  L-Tryptophan
C00079  L-Phenylalanine
C22142  Cyclo(L-Trp-L-Phe)
C22143  N-Methyl-cyclo(L-Trp-L-Phe)
C22144  (-)-Ditryptophenaline
Reference
  Authors
Saruwatari T, Yagishita F, Mino T, Noguchi H, Hotta K, Watanabe K
  Title
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis.
  Journal
Chembiochem 15:656-9 (2014)
DOI:10.1002/cbic.201300751

DBGET integrated database retrieval system