KEGG   NETWORK: N00082
Entry
N00082                      Network                                
Name
Loss of NKX3-1 to PI3K signaling pathway
Definition
NKX3-1* // AKT -| BAD
  Expanded
4824v1 // (207,208,10000) -| 572
Class
nt06272 Prostate cancer
nt06214 PI3K signaling (cancer)
Type
Variant
Pathway
hsa05215  Prostate cancer
Disease
H00024  Prostate cancer
Gene
4824  NKX3-1; NK3 homeobox 1
207  AKT1; AKT serine/threonine kinase 1
208  AKT2; AKT serine/threonine kinase 2
10000  AKT3; AKT serine/threonine kinase 3
572  BAD; BCL2 associated agonist of cell death
Variant
4824v1 (NKX3-1*)  NKX3-1 loss
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:11854455
  Authors
Kim MJ, Cardiff RD, Desai N, Banach-Petrosky WA, Parsons R, Shen MM, Abate-Shen C
  Title
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.
  Journal
Proc Natl Acad Sci U S A 99:2884-9 (2002)
DOI:10.1073/pnas.042688999

  All links  
Pathway (1)   
   KEGG PATHWAY (1)   
Network (1)   
   KEGG VARIANT (1)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (5)   
   KEGG GENES (5)   
Literature (2)   
   PubMed (2)   
All databases (10)   

Download RDF
DBGET integrated database retrieval system