KEGG   NETWORK: N00798
Entry
N00798                      Network                                
Name
Thyroid hormone signaling pathway
Definition
(SLC16A10,SLC16A2) -> T3 -> (THRB,THRA) == RXR => (MYH6,ATP2A2)
  Expanded
(117247,6567) -> C02465 -> (7068,7067) == (6256,6257,6258) => (4624,488)
Class
nt06322 TRH-TSH-TH signaling
Type
Reference
Pathway
hsa04919  Thyroid hormone signaling pathway
Gene
117247  SLC16A10; solute carrier family 16 member 10
6567  SLC16A2; solute carrier family 16 member 2
7068  THRB; thyroid hormone receptor beta
7067  THRA; thyroid hormone receptor alpha
6256  RXRA; retinoid X receptor alpha
6257  RXRB; retinoid X receptor beta
6258  RXRG; retinoid X receptor gamma
4624  MYH6; myosin heavy chain 6
488  ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Metabolite
C02465  Triiodothyronine
Reference
  Authors
Pascual A, Aranda A
  Title
Thyroid hormone receptors, cell growth and differentiation.
  Journal
Biochim Biophys Acta 1830:3908-16 (2013)
DOI:10.1016/j.bbagen.2012.03.012
Reference
  Authors
Ojamaa K
  Title
Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy.
  Journal
Vascul Pharmacol 52:113-9 (2010)
DOI:10.1016/j.vph.2009.11.008

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