| Entry |
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| Name |
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating);
pyruvate dehydrogenase complex
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| Definition |
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
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| Equation |
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|
 |
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| Comment |
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| Reaction class |
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| Enzyme |
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| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
| rn01120 | Microbial metabolism in diverse environments |
| rn01210 | 2-Oxocarboxylic acid metabolism |
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| Module |
| M00307 | Pyruvate oxidation, pyruvate => acetyl-CoA |
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| Orthology |
| K00161 | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] |
| K00162 | pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] |
| K00627 | pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] |
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| Other DBs |
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