KEGG   REACTION: R00286
Entry
R00286                      Reaction                               

Name
UDP-glucose:NAD+ 6-oxidoreductase
Definition
UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + 2 H+
Equation
C00029 + C00001 + 2 C00003 <=> C00167 + 2 C00004 + 2 C00080
Reaction class
RC00001  C00003_C00004
RC00291  C00029_C00167
Enzyme
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00014  Glucuronate pathway (uronate pathway)
M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Orthology
K00012  UDPglucose 6-dehydrogenase [EC:1.1.1.22]
Other DBs
RHEA: 23599

KEGG   RCLASS: RC00291
Entry
RC00291                     RClass                                 

Definition
C1b-C6a:*-O6a:C1y+O1a-C1y+O6a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.22        1.1.1.132       1.1.1.136       1.1.1.186       
1.1.1.336       1.1.1.-         1.1.3.28        1.1.3.39
Pathway
rn00040  Pentose and glucuronate interconversions
rn00051  Fructose and mannose metabolism
rn00053  Ascorbate and aldarate metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00523  Polyketide sugar unit biosynthesis
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Orthology
K00012  UDPglucose 6-dehydrogenase [EC:1.1.1.22]
K00066  GDP-mannose 6-dehydrogenase [EC:1.1.1.132]
K02472  UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
K02474  UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]
K13015  UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136]
K21331  dTDP-alpha-D-glucose dehydrogenase [EC:1.1.1.-]
K22926  UDP-N-acetylglucosamine 6-dehydrogenase [EC:1.1.1.136]

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