KEGG   REACTION: R00707
Entry
R00707                      Reaction                               
Name
(S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase
Definition
(S)-1-Pyrroline-5-carboxylate + NAD+ + 2 H2O <=> L-Glutamate + NADH + H+
Equation
Comment
two-step reaction (see R03314+R00245)
NADPH (see R00708)
Reaction class
RC00001  C00003_C00004
RC00216  C00025_C03912
Enzyme
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Other DBs
RHEA: 16420

KEGG   REACTION: R00708
Entry
R00708                      Reaction                               
Name
(S)-1-pyrroline-5-carboxylate:NADP+ oxidoreductase
Definition
(S)-1-Pyrroline-5-carboxylate + NADP+ + 2 H2O <=> L-Glutamate + NADPH + H+
Equation
Comment
possibly two-step reaction
NADH (see R00707)
Reaction class
RC00001  C00005_C00006
RC00216  C00025_C03912
Enzyme
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Other DBs
RHEA: 24885

KEGG   RCLASS: RC00216
Entry
RC00216                     RClass                                 
Definition
C2x-C6a:N2x+*+*-*+O6a+O6a:C1x-C1b
N2x-N1a:C2x-*:C1y-C1c
Reactant pair
Related class
Reaction
Enzyme
1.2.1.31        1.2.1.88
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]

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