KEGG   REACTION: R01454
Entry
R01454                      Reaction                               

Name
Cholesterol:oxygen oxidoreductase (side-chain-cleaving)
Definition
Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 20alpha-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Equation
Comment
first step of R02724 (R01454+R04854+R03933)
Reaction class
RC00521  C00187_C05500
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00107  Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
Orthology
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]

KEGG   RCLASS: RC00521
Entry
RC00521                     RClass                                 

Definition
C1c-C1d:*-O1a:C1a+C1b+C1y-C1a+C1b+C1y
Reactant pair
Related class
Reaction
Enzyme
1.14.14.-       1.14.15.6
Pathway
rn00140  Steroid hormone biosynthesis
rn00996  Biosynthesis of various alkaloids
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K25060  cucurbitadienol 11-hydroxylase / 11-oxocucurbitadienol 20-hydroxylase [EC:1.14.14.71 1.14.14.-]

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