KEGG   REACTION: R01629
Entry
R01629                      Reaction                               
Name
protocatechuate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Definition
3,4-Dihydroxybenzoate + Oxygen + NADH + H+ <=> Benzene-1,2,4-triol + CO2 + NAD+ + H2O
Equation
Comment
NADPH (see R01630)
Reaction class
RC00001  C00003_C00004
RC00115  C00230_C02814
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Reference
1  [PMID:9352916]
  Authors
Eppink MH, Boeren SA, Vervoort J, van Berkel WJ.
  Title
Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604.
  Journal
J Bacteriol 179:6680-7 (1997)
DOI:10.1128/JB.179.21.6680-6687.1997
Other DBs
RHEA: 30038

KEGG   REACTION: R01630
Entry
R01630                      Reaction                               
Name
protocatechuate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Definition
3,4-Dihydroxybenzoate + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + CO2 + NADP+ + H2O
Equation
Comment
NADH (see R01629)
Reaction class
RC00001  C00005_C00006
RC00115  C00230_C02814
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Reference
1  [PMID:9352916]
  Authors
Eppink MH, Boeren SA, Vervoort J, van Berkel WJ.
  Title
Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604.
  Journal
J Bacteriol 179:6680-7 (1997)
DOI:10.1128/JB.179.21.6680-6687.1997
Other DBs
RHEA: 30042

KEGG   RCLASS: RC00115
Entry
RC00115                     RClass                                 
Definition
C8y-C8y:C6a+*-*+O1a:C8x+C8x-C8x+C8x
Reactant pair
Related class
Reaction
Enzyme
1.14.13.27      1.14.13.64      1.14.13.114     1.14.99.-
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00362  Benzoate degradation
rn00627  Aminobenzoate degradation
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K14974  6-hydroxynicotinate 3-monooxygenase [EC:1.14.13.114]

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