KEGG   REACTION: R01837
Entry
R01837                      Reaction                               

Name
3beta-Hydroxyandrost-5-en-17-one:NAD+ 3-oxidoreductase/delta5-delta-4 isomerase
Definition
Dehydroepiandrosterone + NAD+ <=> Androstenedione + NADH + H+
Equation
Comment
NADP+ (see R01839)
Reaction class
RC00001  C00003_C00004
RC00146  C00280_C01227
Enzyme
1.1.1.145       5.3.3.1
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Other DBs
RHEA: 43935

KEGG   RCLASS: RC00146
Entry
RC00146                     RClass                                 

Definition
C1x-C2x:*-*:C1x+C2y-C1x+C2y
C2x-C1x:*-*:C2y+C5x-C2y+C1y
C5x-C1y:*-*:C1x+C2x+O5x-C1x+C1x+O1a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.145       1.1.3.6         5.3.3.1
Pathway
rn00140  Steroid hormone biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K03333  cholesterol oxidase [EC:1.1.3.6]
K09588  cytochrome P450 family 90 subfamily A1 [EC:1.14.-.-]
K16045  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]

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