KEGG   REACTION: R01837
Entry
R01837                      Reaction                               
Name
3beta-Hydroxyandrost-5-en-17-one:NAD+ 3-oxidoreductase/delta5-delta-4 isomerase
Definition
Dehydroepiandrosterone + NAD+ <=> Androstenedione + NADH + H+
Equation
C01227 + C00003 <=> C00280 + C00004 + C00080
Comment
NADP+ (see R01839)
Reaction class
RC00001  C00003_C00004
RC00146  C00280_C01227
Enzyme
1.1.1.145       5.3.3.1
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Other DBs
RHEA: 43935

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
Gene (509)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (508)   
All databases (524)   

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KEGG   RCLASS: RC00146
Entry
RC00146                     RClass                                 
Definition
C1x-C2x:*-*:C1x+C2y-C1x+C2y
C2x-C1x:*-*:C2y+C5x-C2y+C1y
C5x-C1y:*-*:C1x+C2x+O5x-C1x+C1x+O1a
Reactant pair
C00187_C00599    C00280_C01227    C00410_C01953
C00535_C04295    C00735_C05489    C01176_C05138
C03205_C05485    C05139_C05140    C05487_C05488
C15795_C15796    C16252_C16253
Related class
Reaction
R01459 R01837 R02216 R02499 R02840 R03327 R04163 R04678
R04849 R07446 R07789 R09920
Enzyme
1.1.1.145       1.1.3.6         1.14.19.79      5.3.3.1
Pathway
rn00140  Steroid hormone biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K03333  cholesterol oxidase [EC:1.1.3.6]
K09588  3beta,22alpha-dihydroxysteroid 3-dehydrogenase [EC:1.14.19.79]
K16045  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]

  All links  
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (16)   
   KEGG ENZYME (4)   
   KEGG REACTION (12)   
Gene (4)   
   KEGG ORTHOLOGY (4)   
All databases (26)   

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