KEGG   REACTION: R01900
Entry
R01900                      Reaction                               

Name
isocitrate hydro-lyase (cis-aconitate-forming)
Definition
Isocitrate <=> cis-Aconitate + H2O
Equation
Reaction class
RC00618  C00311_C00417
Enzyme
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00630  Glyoxylate and dicarboxylate metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00012  Glyoxylate cycle
M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
M00740  Methylaspartate cycle
Orthology
K01681  aconitate hydratase [EC:4.2.1.3]
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
Other DBs
RHEA: 22147

KEGG   RCLASS: RC00618
Entry
RC00618                     RClass                                 

Definition
C1c-C2b:O1a-*:C1c+C6a-C2c+C6a
C1c-C2c:*-*:C1b+C1c+C6a-C1b+C2b+C6a
Reactant pair
Related class
Reaction
Enzyme
4.2.1.3         4.2.1.36        4.2.1.114
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00300  Lysine biosynthesis
rn00630  Glyoxylate and dicarboxylate metabolism
rn00680  Methane metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01681  aconitate hydratase [EC:4.2.1.3]
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
K01705  homoaconitate hydratase [EC:4.2.1.36]
K16792  methanogen homoaconitase large subunit [EC:4.2.1.114]
K16793  methanogen homoaconitase small subunit [EC:4.2.1.114]

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