KEGG   REACTION: R02170
Entry
R02170                      Reaction                               
Name
Penicillin amidohydrolase
Definition
Penicillin + H2O <=> Carboxylate + 6-Aminopenicillanate
Equation
Comment
general reaction (see R04103)
Reaction class
RC00166  C00395_C02954
RC00328  C00060_C00395
Enzyme
Pathway
rn00311  Penicillin and cephalosporin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K01434  penicillin G amidase [EC:3.5.1.11]
K24041  penicillin V amidase [EC:3.5.1.11]
Other DBs
RHEA: 18696

KEGG   RCLASS: RC00166
Entry
RC00166                     RClass                                 
Definition
N1a-N1b:*-C5a:C1y-C1y
Reactant pair
Related class
Reaction
Enzyme
2.3.1.3         2.3.1.4         2.3.1.59        2.3.1.60        
2.3.1.78        2.3.1.81        2.3.1.157       2.3.1.191       
2.3.1.197       2.3.1.201       2.3.1.202       2.3.1.203       
2.3.1.209       2.3.1.210       2.3.1.227       2.3.1.276       
2.3.1.-         2.3.2.19        3.5.1.11        3.5.1.25        
3.5.1.26        3.5.1.33        3.5.1.41        3.5.1.52        
3.5.1.89        3.5.1.93        3.5.1.97        3.5.1.103       
3.5.1.104       3.5.1.105       3.5.1.108       3.5.1.112       
3.5.1.113       3.5.1.115       3.5.1.-         6.3.1.13        
6.3.4.13
Pathway
rn00052  Galactose metabolism
rn00230  Purine metabolism
rn00311  Penicillin and cephalosporin biosynthesis
rn00520  Amino sugar and nucleotide sugar metabolism
rn00523  Polyketide sugar unit biosynthesis
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00540  Lipopolysaccharide biosynthesis
rn00541  O-Antigen nucleotide sugar biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
RModule
RM043  Transamination and N-acetylation in deoxysugar biosynthesis
Orthology
K00621  glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4]
K01434  penicillin G amidase [EC:3.5.1.11]
K01443  N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
K01452  chitin deacetylase [EC:3.5.1.41]
K01945  phosphoribosylamine---glycine ligase [EC:6.3.4.13]
K02079  N-acetylgalactosamine-6-phosphate deacetylase [EC:3.5.1.25]
K02535  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
K02536  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
K02576  heparan sulfate N-deacetylase/N-sulfotransferase NDST1 [EC:3.5.1.- 2.8.2.8]
K02577  heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.5.1.- 2.8.2.8]
K02578  heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.5.1.- 2.8.2.8]
K02579  heparan sulfate N-deacetylase/N-sulfotransferase NDST4 [EC:3.5.1.- 2.8.2.8]
K04042  bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K11788  phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
K12631  puromycin biosynthesis protein Pur6
K12748  glutaryl-7-aminocephalosporanic-acid acylase [EC:3.5.1.93]
K13018  UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase [EC:2.3.1.201]
K13551  2'-N-acetylparomamine deacetylase [EC:3.5.1.112]
K13563  ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase [EC:2.3.2.19]
K13713  fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K15896  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase [EC:2.3.1.202]
K15913  UDP-N-acetylbacillosamine N-acetyltransferase [EC:2.3.1.203]
K16363  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
K16704  dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase [EC:2.3.1.210]
K17078  2'-N-acetylparomamine deacetylase / 2'''-acetyl-6'''-hydroxyneomycin deacetylase [EC:3.5.1.112 3.5.1.113]
K17939  GDP-perosamine N-acetyltransferase [EC:2.3.1.227]
K20583  deacetylase [EC:3.5.1.-]
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
K21379  dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase [EC:2.3.1.209]
K23144  UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
K24041  penicillin V amidase [EC:3.5.1.11]
K24251  dTDP-D-Quip3N acetylase [EC:2.3.1.-]
K24281  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine acetyltransferase [EC:2.3.1.-]
K24303  UDP-N-acetylbacillosamine alanyltransferase

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