KEGG   REACTION: R02207
Entry
R02207                      Reaction                               

Name
20alpha-Hydroxy-4-pregnen-3-one:NAD+ 20-oxidoreductase
Definition
20alpha-Hydroxy-4-pregnen-3-one + NAD+ <=> Progesterone + NADH + H+
Equation
Comment
NADP+ (see R02209)
Reaction class
RC00001  C00003_C00004
RC00139  C00410_C04042
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]

KEGG   REACTION: R02209
Entry
R02209                      Reaction                               

Name
20alpha-Hydroxy-4-pregnen-3-one:NADP+ 20-oxidoreductase
Definition
20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+
Equation
Comment
NAD+ (see R02207)
Reaction class
RC00001  C00005_C00006
RC00139  C00410_C04042
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]

KEGG   RCLASS: RC00139
Entry
RC00139                     RClass                                 

Definition
C1c-C5a:*-*:C1a+C1y+O1a-C1a+C1y+O5a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.53        1.1.1.149
Pathway
rn00140  Steroid hormone biosynthesis
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00038  3alpha(or 20beta)-hydroxysteroid dehydrogenase [EC:1.1.1.53]
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
K20595  gentamicin-X2/G418 6'-oxidase

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