KEGG   REACTION: R02208
Entry
R02208                      Reaction                               

Name
5alpha-pregnane-3,20-dione:NADP+ delta4-oxidoreductase
Definition
5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00145  C00410_C03681
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
Orthology
K12343  3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345  3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
Other DBs
RHEA: 21955

KEGG   RCLASS: RC00145
Entry
RC00145                     RClass                                 

Definition
C1x-C2x:*-*:C1y+C5x-C2y+C5x
C1y-C2y:*-*:C1x+C1x+C1z-C1x+C2x+C1z
Reactant pair
Related class
Reaction
Enzyme
1.3.1.3         1.3.1.22        1.3.1.114       1.3.1.115       
1.3.1.116       1.3.99.5        1.3.99.6
Pathway
rn00120  Primary bile acid biosynthesis
rn00140  Steroid hormone biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K00251  3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K09591  steroid 5-alpha-reductase [EC:1.3.1.22]
K12343  3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345  3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
K16051  3-oxo-5alpha-steroid 4-dehydrogenase [EC:1.3.99.5]

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