KEGG   REACTION: R02356
Entry
R02356                      Reaction                               

Definition
Estrone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxyestrone + NADP+ + H2O
Equation
Reaction class
RC00001  C00005_C00006
RC00704  C00468_C05300
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Orthology
K07424  cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17690  cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]

KEGG   RCLASS: RC00704
Entry
RC00704                     RClass                                 

Definition
C1x-C1y:*-O1a:C1x+C5x-C1x+C5x
Reactant pair
Related class
Reaction
Enzyme
1.14.14.1       1.14.14.-       1.14.15.24      1.14.-.-        
4.2.1.164
Pathway
rn00140  Steroid hormone biosynthesis
rn00523  Polyketide sugar unit biosynthesis
rn00906  Carotenoid biosynthesis
rn00981  Insect hormone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413  cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07414  cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07424  cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K10722  ecdysteroid 2-hydroxylase [EC:1.14.-.-]
K13328  dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase [EC:4.2.1.164]
K15746  beta-carotene 3-hydroxylase [EC:1.14.15.24]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17690  cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17691  cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K23037  beta-carotene 4-ketolase/3-hydroxylase [EC:1.14.99.63 1.14.15.24 1.14.99.-]

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