KEGG   REACTION: R02443
Entry
R02443                      Reaction                               

Name
naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Naringenin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Pentahydroxyflavanone + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C00509 + 2 C03024 + 2 C00007 <=> C05911 + 2 C03161 + 2 C00001
Comment
flavonoid 3',5'-hydroxylase
flavonoid 3',5'-monooxygenase
two-step reaction (see R02442+R04902)
Enzyme

KEGG   REACTION: R02442
Entry
R02442                      Reaction                               

Name
naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Definition
Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
flavonoid 3'-hydroxylase
flavonoid 3'-monooxygenase
first step of two-step reaction (see R02443, R02442+R04902)
Reaction class
RC00046  C00509_C05631
Enzyme
Pathway
rn00941  Flavonoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K05280  flavonoid 3'-monooxygenase [EC:1.14.14.82]
K13083  flavonoid 3',5'-hydroxylase [EC:1.14.14.81]
Other DBs
RHEA: 61099

KEGG   REACTION: R04902
Entry
R04902                      Reaction                               

Name
eriodictyol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Eriodictyol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pentahydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
flavonoid 3',5'-hydroxylase
flavonoid 3',5'-monooxygenase
second step of two-step reaction (see R02443, R02442+R04902)
Reaction class
RC00046  C05631_C05911
Enzyme
Pathway
rn00941  Flavonoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K13083  flavonoid 3',5'-hydroxylase [EC:1.14.14.81]
Other DBs
RHEA: 61103

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