KEGG   REACTION: R03325
Entry
R03325                      Reaction                               
Name
17alpha,20alpha-Dihydroxypregn-4-en-3-one:NADP+ 20-oxidoreductase
Definition
17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
Equation
C04518 + C00006 <=> C01176 + C00005 + C00080
Comment
NAD+ (see R03324)
Reaction class
RC00001  C00005_C00006
RC00228  C01176_C04518
Enzyme
1.1.1.149
Pathway
rn00140  Steroid hormone biosynthesis
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
Other DBs
RHEA: 15860

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (70)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (68)   
All databases (82)   

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KEGG   RCLASS: RC00228
Entry
RC00228                     RClass                                 
Definition
C1c-C5a:*-*:C1a+C1z+O1a-C1a+C1z+O5a
Reactant pair
C01176_C04518    C01907_C12430    C01907_C12433
C12431_C12432
Related class
Reaction
R03325 R06689 R06692 R06694
Enzyme
1.1.1.149       1.14.13.181
Pathway
rn00140  Steroid hormone biosynthesis
rn01057  Biosynthesis of type II polyketide products
rn01110  Biosynthesis of secondary metabolites
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
K15955  13-deoxydaunorubicin hydroxylase [EC:1.14.13.181]
K15956  daunorubicin C-13 ketoreductase

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Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   UMBBD-BT (1)   
Gene (4)   
   KEGG ORTHOLOGY (4)   
All databases (14)   

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