KEGG   REACTION: R03329
Entry
R03329                      Reaction                               

Name
steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11-hydroxylating)
Definition
17alpha-Hydroxyprogesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 21-Deoxycortisol + 2 Oxidized ferredoxin + H2O
Equation
Comment
Oxidized ferredoxin is reduced by NADPH (see R01195)
Reaction class
RC00661  C01176_C05497
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]

KEGG   RCLASS: RC00661
Entry
RC00661                     RClass                                 

Definition
C1x-C1y:*-O1a:C1x+C1y-C1x+C1y
Reactant pair
C00148_C19706    C00280_C05284    C00280_C05296
C00410_C03747    C00410_C05498    C00410_C19726
C00477_C16495    C00535_C05291    C00695_C04483
C00735_C05488    C00808_C03448    C00859_C03579
C00951_C05141    C01078_C04397    C01176_C05497
C01433_C06071    C01512_C11636    C02046_C03325
C02140_C03205    C02528_C03990    C03990_C15515
C03990_C15517    C05487_C05489    C06231_C16432
C08616_C21821    C11864_C11868    C11898_C20151
C15485_C15502    C15500_C15501    C15787_C15788
 » show all
Related class
Reaction
Enzyme
1.14.11.7       1.14.11.11      1.14.11.13      1.14.11.25      
1.14.11.28      1.14.11.35      1.14.11.55      1.14.11.-       
1.14.13.146     1.14.14.1       1.14.14.57      1.14.14.64      
1.14.14.85      1.14.14.120     1.14.14.121     1.14.14.125     
1.14.14.138     1.14.14.168     1.14.14.170     1.14.14.-       
1.14.15.1       1.14.15.4       1.14.15.8       1.14.99.14      
1.14.99.61      1.14.-.-
Pathway
rn00140  Steroid hormone biosynthesis
rn00260  Glycine, serine and threonine metabolism
rn00902  Monoterpenoid biosynthesis
rn00904  Diterpenoid biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00981  Insect hormone biosynthesis
rn00996  Biosynthesis of various alkaloids
rn00997  Biosynthesis of various other secondary metabolites
rn00998  Biosynthesis of various antibiotics
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
K04125  gibberellin 2beta-dioxygenase [EC:1.14.11.13]
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K09590  brassinosteroid-6-oxidase 1 [EC:1.14.-.-]
K10674  ectoine hydroxylase [EC:1.14.11.55]
K10722  ecdysteroid 2-hydroxylase [EC:1.14.-.-]
K12640  brassinosteroid-6-oxidase 2 [EC:1.14.-.-]
K12692  hyoscyamine (6S)-dioxygenase [EC:1.14.11.11]
K18054  2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase [EC:1.14.11.24 1.14.11.25]
K18056  1-deoxypentalenic acid 11beta-hydroxylase [EC:1.14.11.35]
K20512  taxoid 14beta-hydroxylase [EC:1.14.13.146]
K20623  typhasterol/6-deoxotyphasterol 2alpha-hydroxylase
K20980  dihydromonacolin L/monacolin L hydroxylase [EC:1.14.14.124 1.14.14.125]
K21114  steroid 15beta-monooxygenase [EC:1.14.15.8]
K22997  cyclooctat-9-en-7-ol 5-monooxygenase [EC:1.14.99.61]
K23276  7-deoxyloganate 7-hydroxylase [EC:1.14.14.85]
K25488  11-carbonyl-20beta-hydroxycucurbitadienol 2-hydroxylase [EC:1.14.14.-]
K25492  22,26-dihydroxycholesterol 16alpha-hydroxylase [EC:1.14.11.-]

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