Entry |
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Name |
anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)
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Definition |
Anhydrotetracycline + Oxygen + NADPH + H+ <=> 5a,11a-Dehydrotetracycline + NADP+ + H2O
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Equation |
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Reaction class |
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Enzyme |
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Pathway |
rn01057 | Biosynthesis of type II polyketide products |
rn01110 | Biosynthesis of secondary metabolites |
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Module |
M00780 | Tetracycline/oxytetracycline biosynthesis, pretetramide => tetracycline/oxytetracycline |
M00823 | Chlortetracycline biosynthesis, pretetramide => chlortetracycline |
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Orthology |
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Reference |
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Authors |
Pickens LB, Tang Y |
Title |
Oxytetracycline biosynthesis. |
Journal |
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Reference |
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Authors |
Peric-Concha N, Borovicka B, Long PF, Hranueli D, Waterman PG, Hunter IS |
Title |
Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length. |
Journal |
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Other DBs |
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