KEGG   REACTION: R04759
Entry
R04759                      Reaction                               

Name
19-hydroxyandrostenedione,NADPH---hemoprotein reductase:oxygen 19-oxidoreductase
Definition
19-Hydroxyandrost-4-ene-3,17-dione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Oxoandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
Comment
aromatase, ARO
following after R01840
subsequently R02351
Reaction class
RC00893  C05290_C05297
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K07434  aromatase [EC:1.14.14.14]
Other DBs
RHEA: 38206

KEGG   RCLASS: RC00893
Entry
RC00893                     RClass                                 

Definition
C1b-C4a:*-*:C1z+O1a-C1z+O4a
Reactant pair
Related class
Reaction
Enzyme
1.14.11.12      1.14.13.246     1.14.13.-       1.14.14.14      
1.14.14.86      1.14.14.111     1.14.14.115     1.14.14.126     
1.14.14.145     1.14.14.154     1.14.15.4       1.14.15.5       
1.14.15.36      1.14.18.9       1.14.18.10
Pathway
rn00140  Steroid hormone biosynthesis
rn00521  Streptomycin biosynthesis
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K05282  gibberellin-44 dioxygenase [EC:1.14.11.12]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K07434  aromatase [EC:1.14.14.14]
K12918  cytochrome P450 monooxygenase 2
K14040  abieta-7,13-dien-18-ol hydroxylase [EC:1.14.14.145]
K21292  ent-kaurene oxidase [EC:1.14.14.86]

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