KEGG   REACTION: R09191
Entry
R09191                      Reaction                               

Name
S-adenosyl-L-methionine:4-amino-anhydrotetracycline N-methyltransferase
Definition
4-Amino-anhydrotetracycline + 2 S-Adenosyl-L-methionine <=> Anhydrotetracycline + 2 S-Adenosyl-L-homocysteine
Equation
C06654 + 2 C00019 <=> C02811 + 2 C00021
Reaction class
RC00003  C00019_C00021
RC01515  C02811_C06654
Enzyme
Pathway
rn00253  Tetracycline biosynthesis
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00780  Tetracycline/oxytetracycline biosynthesis, pretetramide => tetracycline/oxytetracycline
M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Orthology
K14255  4-amino-anhydrotetracycline N4-methyltransferase [EC:2.1.1.335]

KEGG   RCLASS: RC01515
Entry
RC01515                     RClass                                 

Definition
N1a-N1c:*+*-C1a+C1a:C1y-C1y
Reactant pair
Related class
Reaction
Enzyme
2.1.1.234       2.1.1.235       2.1.1.236       2.1.1.324       
2.1.1.335       2.1.1.-
Pathway
rn00253  Tetracycline biosynthesis
rn00523  Polyketide sugar unit biosynthesis
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
RModule
RM035  Transamination and N,N-dimethylation in polyketide biosynthesis
Orthology
K13307  dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.235]
K13311  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.234]
K13326  dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.- 2.1.1.234]
K13330  dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase [EC:2.1.1.324]
K13332  N,N-dimethyltransferase
K14255  4-amino-anhydrotetracycline N4-methyltransferase [EC:2.1.1.335]
K20682  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase [EC:2.1.1.236]
K21327  N-methyltransferase [EC:2.1.1.-]

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