KEGG   REACTION: R12118
Entry
R12118                      Reaction                               

Name
sterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
Definition
14alpha-Methylsteroid + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Delta14-Steroid + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Equation
C21918 + 3 C03024 + 3 C00007 <=> C21919 + C00058 + 3 C03161 + 4 C00001
Comment
three-step reaction (see R12119+R12120+R12121)
Enzyme

KEGG   REACTION: R12119
Entry
R12119                      Reaction                               

Definition
14alpha-Methylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Hydroxymethylsteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the first step of three-step reaction (see R12118, R12119+R12120+R12121)
Reaction class
RC00257  C21918_C21920
Enzyme

KEGG   REACTION: R12120
Entry
R12120                      Reaction                               

Definition
14alpha-Hydroxymethylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Formylsteroid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
Comment
the second step of three-step reaction (see R12118, R12119+R12120+R12121)
Reaction class
RC00893  C21920_C21921
Enzyme

KEGG   REACTION: R12121
Entry
R12121                      Reaction                               

Definition
14alpha-Formylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Delta14-Steroid + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the last step of three-step reaction (see R12118, R12119+R12120+R12121)
Enzyme

DBGET integrated database retrieval system