KEGG   REACTION: R12270
Entry
R12270                      Reaction                               

Name
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Definition
8beta-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eupatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
Comment
two-step reaction (see R12267+R12268)
Reaction class
RC02572  C09440_C22049
Enzyme

KEGG   REACTION: R12267
Entry
R12267                      Reaction                               

Name
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Definition
8beta-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the first step of two-step reaction (see R12270, R12267+R12268)
Reaction class
RC00524  C22049_C22050
Enzyme

KEGG   REACTION: R12268
Entry
R12268                      Reaction                               

Definition
6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Eupatolide + H2O
Equation
Comment
spontaneous
the second step of two-step reaction (see R12270, R12267+R12268)
Enzyme

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