KEGG   Acanthamoeba castellanii: ACA1_360410
Entry
ACA1_360410       CDS       T02667                                 
Name
(RefSeq) phosphoinositide 3kinase family, accessory domain (pik domain) domain containing protein
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
acan  Acanthamoeba castellanii
Pathway
acan00562  Inositol phosphate metabolism
acan01100  Metabolic pathways
acan04070  Phosphatidylinositol signaling system
acan04081  Hormone signaling
acan04145  Phagocytosis
acan04517  IgSF CAM signaling
acan04518  Integrin signaling
acan04620  Toll-like receptor signaling pathway
acan05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:acan00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    ACA1_360410
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    ACA1_360410
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    ACA1_360410
   04517 IgSF CAM signaling
    ACA1_360410
   04518 Integrin signaling
    ACA1_360410
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    ACA1_360410
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    ACA1_360410
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    ACA1_360410
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:acan04131]
    ACA1_360410
Enzymes [BR:acan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     ACA1_360410
Membrane trafficking [BR:acan04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    ACA1_360410
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd HEAT_2 Peptidase_C14
Other DBs
NCBI-GeneID: 14923995
NCBI-ProteinID: XP_004352502
UniProt: L8HCV8
Position
Unknown
AA seq 1368 aa
MSLSVDPMVPAAMRPGEDVFTANLASAITAKSQLKSSGSPSKDPLSSSGGADAVRRPSNA
LPSRFGISLVVPSGSQVDLKCGVGDTAADFIRSNFNKMKFMLGATANAAHYVLQTPDGET
LASDALVASSAYVEQCVLGKSQPSLFLKPRERGPAPLPPMRPYAMTTSSAPASPSSLSTS
PRRLPFSYIPTATPPPSVAALSMASPSSSLELSPPSSPSSSLSSTPRTSNAHSPFSLSPA
TSFVAHTQSGDEIPTSPLATTSGRATSSDLSSSPPVIDIDVHEDEPFDLQVLLAGAVTTI
VECKPTDTAGNVLTRLDIPDSRLHCYSLATPASNALDGALVLSKLEYIRECRRHYILPQL
RVVEDTPSLSKEEKKENKDIGGLIGQKLCWTNVEDEISAFRKTMARVRKEVVLAEELRGL
DDGELNIRLSGAPNPTVDRLLIRVVLPLEKKSTNLLVTNDRGMETADSFLQRLLQLPLFS
TSGFYHAQTHPHLLLRAKGRLEHIVGKYPLLAFGMECVESKRWPKLVLLKRSEDYIALAK
PKQDDASASSSSTTTAGWTSARVPRTPRVRATPFSPRLGGASEGTRDVGESETGPTAIQE
VKAGEATEWEENCEGDQVDDEEEALAPRYDHALMAGELVRWDQKSHISLWELENRPFRIK
VMGVERTNELGCPSWRKFSPDLAPDDVIGSLYVHVGVYYGGQLLVKDAVTKPVPCSANPR
WGQWLTFDDLLFSNESRVCCTLYAKTARDTDAIPLAWANFNIFDYKHELRSGLHTLSMWP
DGPANPIGTCVGNAGFAHATQLALELDSFPLPVVFPTDGTTGKTKGPNRNSCLVLGGGEE
ELELVEEVEKILAMDSLHRLTPTQKKIVNTLRGYCLARPNALPKFLQAVNYADHISVQEM
HSLLGFFRQPTAVEALELLDSKFPDAKVRDHAVECLEALSHDELLDYLLQLVQVIKYEAY
HDSGNAFYWYLRSEVHAPEISERYSLILEAYLRGSPSHRRRLHRQNQALNAIYHVGTKIK
GLNSIQHSSRLSQDEAIKTEEERAEVLSAALAVIKLPSTFGLPLRADMEVADLLTDKCKF
MDSKKRPLWLVFENAQPARPPIYTIFKCGDDLRQDMLTLQMLRIMDKMWKNEGYDLCVTP
YGCIATGADMGFIENSATTAAVAKESGYGARGAFKEDPLKNWLLKHNPTKEQWDAALRNF
IRSCAAYCVATYVLGIGDRHNDNVMVTKDGRLFHIDFGHFLGNFKKKFGFKRERAPFVLT
PDHAFVMGGRGSEGFTLFITTACRAYNILRKHAMGTSLLNLTVFLLEQTGIPELKSAEDL
EYLRYAFATDLDDNAAAARFTELIHAALDCWTTRFNNAIHLIAHGGKG
NT seq 4107 nt   +upstreamnt  +downstreamnt
atgtcgctgtcggtcgaccccatggtgccggcggcgatgcggccgggcgaagacgtgttc
acggccaacctggcgtcggcgatcacggccaagagccagctcaagtcctccgggtcccct
tccaaagacccgctctcgtcctccggaggcgccgatgccgtgcgccggccttccaacgct
ctcccctcgcgctttggcatctccctcgtcgtcccgtcaggctcgcaggtggatctgaaa
tgtggtgtgggcgacacagcagccgacttcatccgctccaactttaacaagatgaagttt
atgctgggcgcgacagcgaatgcagcccactatgtgctgcaaacgcccgacggagagaca
ctcgcctcggatgcgctggtcgcgagcagtgcctacgtggagcagtgcgtgctgggcaaa
tcgcagccctcactcttcctcaagccccgagagcgcggccctgctccgctgccgcccatg
cggccgtatgccatgaccacctcgtcggcgcccgcctctccctcttccctctccacctcc
ccgcggcgactgcccttcagctacatacccaccgcgacaccgccgccgagcgtggcggcc
ctatccatggccagtccgtcgtcgtcgctcgaattgtcgccgccctcatcgccctcgtca
tcgctgtcctcgacaccgcgcacgtccaacgcccactcgcccttttccctctcgccggcc
acctccttcgtggcgcacactcagtcgggcgatgagatcccgacctcgcccctcgccacc
acgtccgggcgtgctacgtcatccgatctctcttcgtcgccgccggtcatcgacatcgat
gtccacgaggacgagccgtttgacctgcaggtgctgctggcgggggcggtgacaacgatc
gtggaatgcaagccgaccgacactgcaggcaacgtgctcacgcgtctggacattcccgac
tcccgcctgcattgctacagtctggccactcctgcctcaaacgccctcgatggcgctctc
gtgctgtccaagctcgagtacattcgcgagtgcagaaggcactacatcctcccccagcta
cgggtggtcgaggacacaccgagcctgagcaaagaggaaaagaaagaaaacaaagacatt
ggcggattgatcgggcagaagctgtgttggaccaatgtagaggatgagatttcagcgttc
cgcaagaccatggccagagtgaggaaagaagtggtgctggccgaagaactgcgaggattg
gacgacggggagctcaacatccgattgtccggcgcgcccaatcccactgtcgatcgcctg
ctcatccgggtcgtgctgccgctcgagaagaagagcaccaacctgctcgtcaccaacgat
aggggaatggagactgcggattccttcctgcagcgactgcttcagctgcccctgttctcg
acctccggcttctaccacgcccagacgcacccgcacctcctgctacgagccaagggcagg
ctggaacacatcgtgggcaagtacccgttgctggcctttggtatggaatgcgtggaaagt
aagcgttggccgaagctggtgctgctcaagcgatcggaggactacatcgcgctggccaaa
cccaaacaagacgacgcttccgcatcatcgtcgtcaaccaccactgccgggtggacctcc
gcccgcgtcccgcgcaccccacgagtgcgtgcgacaccattttcgccgcgcttgggagga
gccagcgaggggacgagagacgtcggcgagtcggagacagggccgacagcgatacaagag
gtgaaggcgggcgaagcgacggagtgggaggagaattgcgagggagaccaggtcgacgat
gaagaggaggccctcgcgccgcgctatgaccacgctctcatggccggcgagctggtgagg
tgggaccaaaagtcgcacatctccctgtgggagctggagaaccggccatttcgaatcaaa
gtgatgggcgtggagaggaccaacgaattgggctgtccctcgtggaggaagttctccccc
gatctcgctccggacgacgtcatcggctctctttacgtccacgtcggggtgtactacgga
ggacagctgctggtgaaggacgcggtcacaaagcccgtgccgtgttctgccaacccgcgc
tgggggcagtggctcacgttcgacgatctactcttctcgaatgaatcgcgcgtttgctgc
accctctatgcgaaaacggccagagacacggacgcaattccgcttgcttgggccaacttc
aacatcttcgactacaagcacgaactacggtccggcttgcacaccctctccatgtggccg
gacggaccggccaacccgatcggcacatgcgtgggtaatgcgggctttgcgcacgccacg
cagctcgcactcgagctcgactcctttcccctccccgtcgtctttcccaccgatggcacg
acgggcaagacgaagggacccaaccgcaattcttgcctggtgctgggcggcggagaggaa
gaactggagctggtggaagaggtggagaagatactcgccatggactctcttcaccggctg
accccgacccaaaagaagatcgtcaacacgctgcgcggctactgtctggcgcggcccaac
gccttgccgaagtttttgcaggccgtcaactatgccgaccacatatctgtccaggagatg
cactcgttgctgggcttcttcagacagccaacggcagtcgaggccctggagcttctcgac
tccaagttccccgatgctaaggtgcgagatcatgcggtcgaatgtctggaggccttgtcc
cacgatgagctgctcgactacctcctccagttggtgcaggtcatcaagtatgaagcctat
catgactctggcaatgcgttctattggtacctgcgatcggaggtgcacgcgccggagatc
tcggagcggtacagcctcatcctcgaggcctacctccgcggctcgccgtcccaccgtcgt
cggctgcatcgacagaaccaagccctcaacgccatctaccacgtcggaactaaaatcaag
ggcttgaactccattcaacattcatctcgtctgtcccaggacgaagcgatcaagacggaa
gaggagcgggccgaggtgctgagcgccgcactggcggtgatcaagctgccctccaccttt
gggctgccgctgcgggcggacatggaggtggcagatctcctcacagacaagtgcaagttc
atggactccaagaagcggccgctgtggctcgtctttgagaacgcccaacccgcgcgaccg
cccatctacaccattttcaagtgtggcgacgatctccgtcaggacatgttgacgctgcag
atgcttcgaatcatggacaagatgtggaaaaacgagggctacgatctgtgtgtgacgccc
tatggctgcattgccaccggggcggacatgggtttcattgagaactcggcaaccacggct
gcagtcgccaaggagtcgggctacggggccagaggcgccttcaaggaggacccgctcaag
aactggctgctcaagcacaaccccaccaaagaacagtgggacgcggcgctgagaaacttc
atccgatcttgtgcggcgtactgcgtggccacctatgtgctggggattggcgatcgacac
aacgacaacgtgatggtgaccaaggacggccgactgttccacatcgacttcggccatttc
ctggggaacttcaaaaagaaattcggcttcaagcgggaacgcgctccgttcgtgctgacc
ccggaccacgccttcgtgatgggcggtcgcggcagcgaaggattcacactcttcattaca
actgcttgccgcgcctacaacatccttcgcaagcacgccatgggaacgagcctgctaaac
ttgaccgtattcctcctcgagcagacgggcattccagagctgaagagcgcagaggacctg
gagtacctgcgctacgccttcgcaaccgatcttgacgacaatgcagccgcagcccgcttt
accgagctcatacacgccgccctcgactgctggaccacacgcttcaacaacgccatccac
ctcatcgcgcacggcggcaagggctga

  All links  
Gene (69)   
   RefGene (66)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (78)   

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