KEGG   Actinoplanes sp. NBRC 14428: Asp14428_47270
Entry
Asp14428_47270    CDS       T08315                                 
Symbol
ddlA_1
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
actr  Actinoplanes sp. NBRC 14428
Pathway
actr00470  D-Amino acid metabolism
actr00550  Peptidoglycan biosynthesis
actr01100  Metabolic pathways
actr01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:actr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Asp14428_47270 (ddlA_1)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Asp14428_47270 (ddlA_1)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Asp14428_47270 (ddlA_1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:actr01011]
    Asp14428_47270 (ddlA_1)
Enzymes [BR:actr01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Asp14428_47270 (ddlA_1)
Peptidoglycan biosynthesis and degradation proteins [BR:actr01011]
 Precursor biosynthesis
  Amino acid ligase
   Asp14428_47270 (ddlA_1)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp ATP-grasp_3 CPSase_L_D2 ATPgrasp_ST RimK TTL
Other DBs
NCBI-ProteinID: BCJ53252
Position
complement(5071800..5072759)
AA seq 319 aa
MGTSTEPHVLVLAGGLSYERDVSLRSGRRVLDALRGAGLSAELRDADVSLLPTLREDPPD
AVVIALHGATGEDGSLRGVLDLCEVPYVGCTAAASRLAWDKPSAKSMLREKGIRTPDWVA
LPHDRFSELGAVAVLDRIADRLGLPLMVKPAQGGSGLGAAVVRDPAELPAAMVGCFAYDS
TALVERYVAGMDVAVSVLDLGEGPIALPAVEIVPRNGVYDYAARYTAGLTTWHTPARLSP
PVAESVASTALAAHEALGLRDLSRVDLIVDADGVPHVLEVNVSPGMTETSLLPLAVQAGG
LDFGKILATLVSRAAARRG
NT seq 960 nt   +upstreamnt  +downstreamnt
atgggtacgtccacagaaccgcatgtcctcgtcctcgcaggcggcctctcgtacgagcgc
gacgtctcactgcgctccggccgccgcgtcctggacgcgctacgcggcgcgggcctgtcg
gcggagctgcgcgacgcggacgtatccctgctgccgacgctccgggaggaccctccggac
gcggtggtgatcgcactccacggggcgaccggcgaggacggctcgctccggggagtgctc
gatctgtgcgaggtcccgtacgtcggctgcacggcggcggcctcccggctcgcctgggac
aagccgtcggccaagtcgatgctgcgcgagaagggcatccgtacgccggactgggtcgcc
ctcccgcacgaccgcttctcggagctcggggcggtggcggtgctggaccggatcgccgac
cgcctcggcctcccgctgatggtgaagccggcccagggcggctcgggcctgggggctgcc
gtggtccgcgacccggccgaactcccggcggcgatggtgggctgcttcgcgtacgactcg
accgcgctcgtggaacggtacgtcgcgggcatggacgtggcggtctcggtcctggacctg
ggggagggcccgatcgccctgccggcggtggagatcgtcccccgcaacggcgtgtacgac
tacgcggcccggtacacggccggcctgaccacctggcacaccccggcccgcctgtccccg
ccggtggccgaatcggtggcatcgacggccctggccgcgcacgaggccctggggctccgc
gacctgtcgcgggtcgacctgatcgtggatgcggacggggtgccgcacgtgctggaggtc
aacgtctcgccggggatgacggagacgtcgttgctgccgctggcggtgcaggcaggcggc
ctggacttcggcaagatcctggcgacgctggtgagccgggcggccgctcgccgaggctag

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