KEGG   Antechinus flavipes (yellow-footed antechinus): 127539641
Entry
127539641         CDS       T08818                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
afz  Antechinus flavipes (yellow-footed antechinus)
Pathway
afz00562  Inositol phosphate metabolism
afz01100  Metabolic pathways
afz04015  Rap1 signaling pathway
afz04020  Calcium signaling pathway
afz04022  cGMP-PKG signaling pathway
afz04062  Chemokine signaling pathway
afz04070  Phosphatidylinositol signaling system
afz04071  Sphingolipid signaling pathway
afz04072  Phospholipase D signaling pathway
afz04081  Hormone signaling
afz04082  Neuroactive ligand signaling
afz04261  Adrenergic signaling in cardiomyocytes
afz04270  Vascular smooth muscle contraction
afz04310  Wnt signaling pathway
afz04371  Apelin signaling pathway
afz04540  Gap junction
afz04611  Platelet activation
afz04613  Neutrophil extracellular trap formation
afz04621  NOD-like receptor signaling pathway
afz04713  Circadian entrainment
afz04720  Long-term potentiation
afz04723  Retrograde endocannabinoid signaling
afz04724  Glutamatergic synapse
afz04725  Cholinergic synapse
afz04726  Serotonergic synapse
afz04728  Dopaminergic synapse
afz04730  Long-term depression
afz04742  Taste transduction
afz04750  Inflammatory mediator regulation of TRP channels
afz04911  Insulin secretion
afz04912  GnRH signaling pathway
afz04915  Estrogen signaling pathway
afz04916  Melanogenesis
afz04918  Thyroid hormone synthesis
afz04919  Thyroid hormone signaling pathway
afz04921  Oxytocin signaling pathway
afz04922  Glucagon signaling pathway
afz04924  Renin secretion
afz04925  Aldosterone synthesis and secretion
afz04926  Relaxin signaling pathway
afz04927  Cortisol synthesis and secretion
afz04928  Parathyroid hormone synthesis, secretion and action
afz04929  GnRH secretion
afz04933  AGE-RAGE signaling pathway in diabetic complications
afz04934  Cushing syndrome
afz04935  Growth hormone synthesis, secretion and action
afz04961  Endocrine and other factor-regulated calcium reabsorption
afz04970  Salivary secretion
afz04971  Gastric acid secretion
afz04972  Pancreatic secretion
afz04973  Carbohydrate digestion and absorption
afz05010  Alzheimer disease
afz05016  Huntington disease
afz05017  Spinocerebellar ataxia
afz05022  Pathways of neurodegeneration - multiple diseases
afz05142  Chagas disease
afz05143  African trypanosomiasis
afz05146  Amoebiasis
afz05163  Human cytomegalovirus infection
afz05200  Pathways in cancer
afz05415  Diabetic cardiomyopathy
afz05417  Lipid and atherosclerosis
Module
afz_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:afz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    127539641
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    127539641
   04310 Wnt signaling pathway
    127539641
   04371 Apelin signaling pathway
    127539641
   04020 Calcium signaling pathway
    127539641
   04070 Phosphatidylinositol signaling system
    127539641
   04072 Phospholipase D signaling pathway
    127539641
   04071 Sphingolipid signaling pathway
    127539641
   04022 cGMP-PKG signaling pathway
    127539641
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    127539641
   04081 Hormone signaling
    127539641
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    127539641
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127539641
   04613 Neutrophil extracellular trap formation
    127539641
   04621 NOD-like receptor signaling pathway
    127539641
   04062 Chemokine signaling pathway
    127539641
  09152 Endocrine system
   04911 Insulin secretion
    127539641
   04922 Glucagon signaling pathway
    127539641
   04929 GnRH secretion
    127539641
   04912 GnRH signaling pathway
    127539641
   04915 Estrogen signaling pathway
    127539641
   04921 Oxytocin signaling pathway
    127539641
   04926 Relaxin signaling pathway
    127539641
   04935 Growth hormone synthesis, secretion and action
    127539641
   04918 Thyroid hormone synthesis
    127539641
   04919 Thyroid hormone signaling pathway
    127539641
   04928 Parathyroid hormone synthesis, secretion and action
    127539641
   04916 Melanogenesis
    127539641
   04924 Renin secretion
    127539641
   04925 Aldosterone synthesis and secretion
    127539641
   04927 Cortisol synthesis and secretion
    127539641
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127539641
   04270 Vascular smooth muscle contraction
    127539641
  09154 Digestive system
   04970 Salivary secretion
    127539641
   04971 Gastric acid secretion
    127539641
   04972 Pancreatic secretion
    127539641
   04973 Carbohydrate digestion and absorption
    127539641
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    127539641
  09156 Nervous system
   04724 Glutamatergic synapse
    127539641
   04725 Cholinergic synapse
    127539641
   04728 Dopaminergic synapse
    127539641
   04726 Serotonergic synapse
    127539641
   04720 Long-term potentiation
    127539641
   04730 Long-term depression
    127539641
   04723 Retrograde endocannabinoid signaling
    127539641
  09157 Sensory system
   04742 Taste transduction
    127539641
   04750 Inflammatory mediator regulation of TRP channels
    127539641
  09159 Environmental adaptation
   04713 Circadian entrainment
    127539641
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127539641
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    127539641
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    127539641
   05142 Chagas disease
    127539641
   05143 African trypanosomiasis
    127539641
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127539641
   05016 Huntington disease
    127539641
   05017 Spinocerebellar ataxia
    127539641
   05022 Pathways of neurodegeneration - multiple diseases
    127539641
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127539641
   05415 Diabetic cardiomyopathy
    127539641
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    127539641
   04934 Cushing syndrome
    127539641
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:afz04131]
    127539641
Enzymes [BR:afz01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     127539641
Membrane trafficking [BR:afz04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    127539641
 Endocytosis
  Macropinocytosis
   Phospholipase C
    127539641
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 127539641
NCBI-ProteinID: XP_051819835
Position
6
AA seq 1000 aa
MAGARPGVHALQLEPPAVAEILKRGSKFIKWDEEASSRNLVTLRVDPHGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPETKPEDKLVTIVAGPDPVNTTFLNF
MAVQEDTAKIWADELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSQSIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLLEFVNQKQRDPRLNEVLYPPLRPAQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENSILPPETLDLSNDMTQPLSSYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPFPVILSFENHVDSAK
QQAKMAEYCRTIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHHPPLNLGEG
SVRKRPLEQSNSALSESSVLTEPSSPQLGSPSSEACSTLSNEEDLLGANPEPRKSIDREA
ESEEEEEEEPPDPKKTSTDEGTASSEVNATEEMSTLVNYVEPVKFKSFEVARKRNKSYEM
SSFVETKALEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNAGCQLVALNFQ
TLDLPMQLNAGVFEYNGRSGYLLKPEFMRRQDKSFDPFTEGIVDGIVANALRVKVISGQF
LSDRKVSIYVEVDLFGLPADTRRKYRTRPSQGNSFNPVWDEEPFDFPKVVLPTLASLRVA
AFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLIYTEASDYIPDDHQDYAE
ALINPIKHVSLMDQRSKQLAALMGESEAAPETAEKLPSQKPDHPQFKRSIHGCTEFVPSQ
PPGSGTSPTSPVINRPGQCDELVASILGEVSVAPWRSFGPTSPWGSFAAARSGTCGSCRR
SIRERRWRSRGGSSAPWPSTGGRWKRGARAGARRRRRRKR
NT seq 3003 nt   +upstreamnt  +downstreamnt
atggccggcgcccggcccggggtgcacgcgctgcaactggagcctccggcggtggccgag
atcttaaaacggggcagcaagttcatcaagtgggatgaggaggcttccagtcggaacctg
gtcacgctccgggtggatccccatggcttctttctctactggaccggacccaacatggaa
gtggacacgctggacatcagctcgatccgggacacgcgcacgggccgctacgcccgcctg
cccaaggaccccaagatcagggaagtcctgggtttcggaggtccggaaacgaagccggag
gacaagctggtgaccatagtggctggccccgaccccgtgaacactactttcctcaacttc
atggctgtgcaggaagacactgccaagatctgggcggatgagctcttcaagttggccatg
aacatcctggcccagaacgcgtcccggaacaccttcctccgaaaagcgtacaccaaatta
aagctccaggtgaaccaagatgggcgaatcccggtcaaaaacatcctgaagatgttctct
gctgacaagaagcgagtggagacggcgctggagtcctgcggcctcaattttaaccggagc
cagtcgatccggccagacgagttttccctggagatctttgagagattcctcaataaactg
tgtctccggcccgacatagacaagatcctgctggagatcggtgctaaggggaagccgtac
ctgaccttggagcagctcctggaatttgtcaaccagaagcagcgggacccgaggctgaac
gaggtcctgtaccccccgctccggccggcccaggcccgcctgctcatcgagaaatatgag
cccaaccagcagttcctggagcgagaccagatgtccatggaaggcttcagccgctacctg
ggcggggaggagaacagcatcctgcccccggagactctggacctgagcaacgacatgact
cagcccctcagctcctacttcatcaattcctcacacaacacctacctcacagcggggcag
ctggcggggacctcctcggtggagatgtaccggcaggcgctgctctggggctgccgctgc
gtggagctggacgtgtggaagggccggccgccggaggaggagcccttcatcacgcacggc
ttcaccatgaccaccgaggtgccgctgcgcgacgtgctggaggccatcgccgagaccgcc
ttcaagacctcgcccttccccgtcatcctctccttcgagaaccacgtggactcggcgaag
cagcaggccaagatggccgagtactgccgcaccatcttcggggacgccctgctcatagac
ccgctggacaagtacccgctggccccgggggtgcccctgcccagcccgcaggacctgatg
ggccggatcctggtgaaaaacaaaaagcggcaccacccgcccctgaacctcggcgagggc
tccgtgcgcaagcggcccctggagcagagtaactcggccctgagcgagagctccgtgctc
acggagccctcctccccgcagctcggatcccccagctcggaggcctgctccactctgagc
aatgaggaggatctcctgggcgccaatcctgagccccgaaaatccattgaccgagaggcc
gaaagtgaggaggaggaagaggaggagccgcccgaccccaagaagacctccacagatgag
ggaacagccagcagcgaggtgaacgccactgaggagatgtccacgctggtcaattacgtc
gaacctgtcaagttcaagtcctttgaggtggcccggaagcggaacaagagctacgagatg
tcgtccttcgtggagaccaaggccctggagcagctcaccaagagccccatggagtttgtg
gaatacaacaagcagcagctgagccgcatctaccccaagggcacgcgggtggactcctcc
aactacatgccgcagctcttctggaacgccggctgccagctcgtggccctcaacttccag
acgctcgacctccccatgcagctgaacgcgggcgtgttcgagtacaacgggcgcagcggc
tacctgctcaagcccgagttcatgcggcgccaggacaagtccttcgaccccttcaccgag
ggcatcgtggacggcatcgtggccaacgctctgcgggtcaaggtgatctcgggccagttc
ctgtcggacaggaaggtcagcatctacgtggaggtggatctcttcggcctccccgcggac
acgcggcgcaaataccgcacgcggccctcccaggggaactccttcaaccccgtctgggac
gaggagcccttcgacttccccaaggtggtgctgcccacgctggcctctctccgggtggcg
gccttcgaggaagggggcaagtttgtggggcaccggatcctgccagtctccgccatccgc
tcagggtaccattacatctgcctgaggaatgaagccaaccagcccctgtgtctgcccgct
ctgctcatctacacggaggcttccgactacatccccgatgatcaccaggactacgccgag
gctttgatcaaccccatcaagcacgtcagcctcatggaccagaggtcgaagcagctggcg
gcgctgatgggcgagagcgaggccgctcctgagaccgcggagaaactgccttctcaaaag
ccggaccacccgcagttcaaacggtccatccacggctgcaccgagtttgtgccctcccag
ccccccggctccgggacctcccccaccagccccgtcataaacagaccaggtcagtgcgat
gagctcgtcgccagcatcctgggagaggtgtccgtggccccctggaggagcttcgggccc
acaagtccctggggaagcttcgcagccgccaggagcgggacctgcgggagctgcagaaga
agcatcagagaaaggcggtggcgttcacgcggcggctcctcggcgccctggcccagcacc
ggggggagatggaaaagaggcgcaagagcgggggcccggaggaggaggaggaggaagaga
tga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (12)   

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