KEGG   Acinonyx jubatus (cheetah): 106976432
Entry
106976432         CDS       T04657                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju00562  Inositol phosphate metabolism
aju01100  Metabolic pathways
aju04015  Rap1 signaling pathway
aju04020  Calcium signaling pathway
aju04022  cGMP-PKG signaling pathway
aju04062  Chemokine signaling pathway
aju04070  Phosphatidylinositol signaling system
aju04071  Sphingolipid signaling pathway
aju04072  Phospholipase D signaling pathway
aju04081  Hormone signaling
aju04082  Neuroactive ligand signaling
aju04261  Adrenergic signaling in cardiomyocytes
aju04270  Vascular smooth muscle contraction
aju04310  Wnt signaling pathway
aju04371  Apelin signaling pathway
aju04540  Gap junction
aju04611  Platelet activation
aju04613  Neutrophil extracellular trap formation
aju04621  NOD-like receptor signaling pathway
aju04713  Circadian entrainment
aju04720  Long-term potentiation
aju04723  Retrograde endocannabinoid signaling
aju04724  Glutamatergic synapse
aju04725  Cholinergic synapse
aju04726  Serotonergic synapse
aju04728  Dopaminergic synapse
aju04730  Long-term depression
aju04742  Taste transduction
aju04750  Inflammatory mediator regulation of TRP channels
aju04911  Insulin secretion
aju04912  GnRH signaling pathway
aju04915  Estrogen signaling pathway
aju04916  Melanogenesis
aju04918  Thyroid hormone synthesis
aju04919  Thyroid hormone signaling pathway
aju04921  Oxytocin signaling pathway
aju04922  Glucagon signaling pathway
aju04924  Renin secretion
aju04925  Aldosterone synthesis and secretion
aju04926  Relaxin signaling pathway
aju04927  Cortisol synthesis and secretion
aju04928  Parathyroid hormone synthesis, secretion and action
aju04929  GnRH secretion
aju04933  AGE-RAGE signaling pathway in diabetic complications
aju04934  Cushing syndrome
aju04935  Growth hormone synthesis, secretion and action
aju04961  Endocrine and other factor-regulated calcium reabsorption
aju04970  Salivary secretion
aju04971  Gastric acid secretion
aju04972  Pancreatic secretion
aju04973  Carbohydrate digestion and absorption
aju05010  Alzheimer disease
aju05016  Huntington disease
aju05017  Spinocerebellar ataxia
aju05022  Pathways of neurodegeneration - multiple diseases
aju05142  Chagas disease
aju05143  African trypanosomiasis
aju05146  Amoebiasis
aju05163  Human cytomegalovirus infection
aju05200  Pathways in cancer
aju05415  Diabetic cardiomyopathy
aju05417  Lipid and atherosclerosis
Module
aju_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aju00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106976432
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    106976432
   04310 Wnt signaling pathway
    106976432
   04371 Apelin signaling pathway
    106976432
   04020 Calcium signaling pathway
    106976432
   04070 Phosphatidylinositol signaling system
    106976432
   04072 Phospholipase D signaling pathway
    106976432
   04071 Sphingolipid signaling pathway
    106976432
   04022 cGMP-PKG signaling pathway
    106976432
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    106976432
   04081 Hormone signaling
    106976432
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106976432
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106976432
   04613 Neutrophil extracellular trap formation
    106976432
   04621 NOD-like receptor signaling pathway
    106976432
   04062 Chemokine signaling pathway
    106976432
  09152 Endocrine system
   04911 Insulin secretion
    106976432
   04922 Glucagon signaling pathway
    106976432
   04929 GnRH secretion
    106976432
   04912 GnRH signaling pathway
    106976432
   04915 Estrogen signaling pathway
    106976432
   04921 Oxytocin signaling pathway
    106976432
   04926 Relaxin signaling pathway
    106976432
   04935 Growth hormone synthesis, secretion and action
    106976432
   04918 Thyroid hormone synthesis
    106976432
   04919 Thyroid hormone signaling pathway
    106976432
   04928 Parathyroid hormone synthesis, secretion and action
    106976432
   04916 Melanogenesis
    106976432
   04924 Renin secretion
    106976432
   04925 Aldosterone synthesis and secretion
    106976432
   04927 Cortisol synthesis and secretion
    106976432
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106976432
   04270 Vascular smooth muscle contraction
    106976432
  09154 Digestive system
   04970 Salivary secretion
    106976432
   04971 Gastric acid secretion
    106976432
   04972 Pancreatic secretion
    106976432
   04973 Carbohydrate digestion and absorption
    106976432
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    106976432
  09156 Nervous system
   04724 Glutamatergic synapse
    106976432
   04725 Cholinergic synapse
    106976432
   04728 Dopaminergic synapse
    106976432
   04726 Serotonergic synapse
    106976432
   04720 Long-term potentiation
    106976432
   04730 Long-term depression
    106976432
   04723 Retrograde endocannabinoid signaling
    106976432
  09157 Sensory system
   04742 Taste transduction
    106976432
   04750 Inflammatory mediator regulation of TRP channels
    106976432
  09159 Environmental adaptation
   04713 Circadian entrainment
    106976432
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106976432
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    106976432
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    106976432
   05142 Chagas disease
    106976432
   05143 African trypanosomiasis
    106976432
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106976432
   05016 Huntington disease
    106976432
   05017 Spinocerebellar ataxia
    106976432
   05022 Pathways of neurodegeneration - multiple diseases
    106976432
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106976432
   05415 Diabetic cardiomyopathy
    106976432
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    106976432
   04934 Cushing syndrome
    106976432
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aju04131]
    106976432
Enzymes [BR:aju01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     106976432
Membrane trafficking [BR:aju04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    106976432
 Endocytosis
  Macropinocytosis
   Phospholipase C
    106976432
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 106976432
NCBI-ProteinID: XP_026925392
UniProt: A0A6J2A6D6
Position
9
AA seq 1216 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNDSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFETSKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
NQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EADPGETPSEAPSEARTTPAENGVNHTTSLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKPFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
KLQMDLEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPSLASDPGKLNHRPPSS
EELEGDNPGKEFDTPL
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggccggggctcagcccggagtgcacgctttgcaactcaagccggtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactccactattgttactcca
attattttgaggactgaccctcagggatttttcttttactggacagatcaaaataaggag
acggagctgttagatctcagccttgtcaaggatgccagatgtgggaaacatgccaaagct
cccaaggaccccaaattacgtgaacttttggatgtggggaacatcggacgcttggagcat
cgcatgataacggtggtgtatgggcctgacttagttaacatctcccatttgaatctcgtg
gctttccaagaggaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagagacgcatttctggaaaaagcctatacgaagcttaag
ctgcaagtcactccagaagggcgcattcctctcaaaaacatataccgcttgttctcagca
gaccggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgat
tcaatacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgc
cctcgacctgaaattgataacatcttttctgaatttggtgccaaaagcaaaccatacctt
acagttgatcagatgatggattttatcaacctgaagcagcgagatcctcggctaaatgaa
atactttacccacctttaaagcaagagcaagtccaagtactgattgagaagtatgagccc
aacgatagccttgccaaaaaaggacagatatcagtggatggctttatgcgctatctgagt
ggagaagaaaatggagtcgtttcgcctgagaaactggatttgaatgaagatatgtctcag
cccctttctcactatttcatcaattcctcacacaacacctacctcacagctggccagttg
gctggaaattcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg
gagttggactgctggaaaggacggactgcggaagaggaaccagtcatcacccatgggttc
accatgacaactgaaatatccttcaaggaagtgatagaagcaattgctgagtgtgcattt
aagacgtcaccttttccaattctgctttcatttgagaaccacgtagattccccaaagcag
caagccaagatggcagagtattgccgactgatctttggagatgctcttctcatggaacca
ctggaaaaatacccactggaatctggagttcctcttccaagccctatggatttaatgtac
aaaattttggtgaaaaataagaagaaatcgcataagtcatcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacgtacagtgactcctccagcgtgtttgagccctca
tctccaggagccggggaagctgatactgagagtgacgacgatgacgatgatgacgactgt
aaaaaatcttcaatggatgagggtactgctggcagtgaggccatggccacagaagagatg
tctaacctggtgaactatattcagccagtcaagtttgagtcctttgaaacttcaaaaaaa
agaaatagaagttttgaaatgtcttccttcgtggaaaccaaaggactcgagcaactgaca
aagtctccagtggaatttgtagaatataacaaaatgcagctcagcaggatatatccaaaa
ggaacccgtgtggattcatccaactacatgcctcagctcttctggaatgctggttgccaa
atggttgcacttaattttcaaactgtggacctggctatgcaaataaatatggggatgtat
gaatacaatgggaaaagcggctacagattaaagccagagttcatgaggagacccgacaag
cactttgatccattcaccgaaggcatcgtagatgggatagtggccaacactttatctgtg
aagattatttcaggtcagtttctttctgataagaaagttgggacctatgtggaagtggat
atgtttggtttgcctgtggacacaaggaggaaggcatttaagaccaaaacatcacaagga
aatgctgtaaatcctgtctgggaagaagagcccattgtgttcaaaaaggtggttcttcct
tctctggcctgtttgaggatagcagtttatgaagaaggaggtaaatttatcggtcaccgg
atcttgcctgtacaggcaattcggccaggctatcactacatctgtctgcggaatgagagg
aaccagcctctgatgctcccagctgtctttgtctacatagaggtgaaagactatgtccca
gatacatatgcagatgtgattgaagctttgtcaaatccaatacgatatgtgaatctgatg
gagcagagagcaaagcaactggctgctctgacactggaagatgaagaagaagtaaagaaa
gaggctgatcctggggaaacaccatcagaagctccaagtgaagccaggacaactccagca
gaaaacggagtgaatcacactacatccctggcacccaaaccaccctcccaggctccccac
agccaaccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagt
gttttaacagaagtggaagcacagactatcgaagagctaaagcaacagaaaccgtttgtg
aaacttcaaaagaagcactacaaagaaatgaaagacctggtgaaaagacaccacaagaaa
accactgaccttatcaaagaacacactacaaaatataatgaaattcagaatgactacttg
agaaggagggcagctttggaaaagacagccaaaaaggatagtaagaaaaaatcagaaccc
agcagtcctgaccatggttcatcaacaattgagcaagatcttgctgccctagatgctgaa
atgacccaaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcga
caagaacagtattacagtgagaaataccagaagcgagaacatattaaactgcttattcag
aaattgacggatgttgccgaagaatgtcagaacaatcagctgaagaagctcaaagaaatc
tgtgagaaggagaagaaggaattaaagaagaaaatggataaaaaaaggcaggagaagatc
acagaagctaaatccaaagacaaaagtcaaatggaagaggaaaagacagagatgatccgg
tcatacatccaggaggtggtacagtacatcaagaggttagaagaggcacaaagtaaacgg
caagaaaaacttgtagagaaacacaaggagatccgtcagcagatcctggatgaaaagccc
aagctgcagatggatctggagcaagagtaccaagacaagttcaaaagactgcccctggag
atcttggagttcgtgcaggaagccatgaaagggaagatcagtgaagatagcaatcacagt
tctgctcctccctccctggcctcagaccctggaaaactgaaccacaggcctccttccagt
gaggagctagaaggggacaacccaggaaaagagtttgatactcctctgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (16)   

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