KEGG   Astyanax mexicanus (Mexican tetra): 103040193
Entry
103040193         CDS       T05042                                 
Symbol
apc2
Name
(RefSeq) adenomatous polyposis coli protein 2
  KO
K02085  adenomatosis polyposis coli protein
Organism
amex  Astyanax mexicanus (Mexican tetra)
Pathway
amex04310  Wnt signaling pathway
amex04519  Cadherin signaling
amex04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:amex00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    103040193 (apc2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    103040193 (apc2)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103040193 (apc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:amex01009]
    103040193 (apc2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:amex03036]
    103040193 (apc2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:amex04812]
    103040193 (apc2)
Protein phosphatases and associated proteins [BR:amex01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     103040193 (apc2)
Chromosome and associated proteins [BR:amex03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    103040193 (apc2)
Cytoskeleton proteins [BR:amex04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     103040193 (apc2)
SSDB
Motif
Pfam: APC_basic Arm_APC_u3 APC_rep APC_N_CC Arm APC_r Suppressor_APC SAMP SSNA1 PEA2_C Sec7-like_HUS DDE_Tnp_IS240 HALZ Par-4_C
Other DBs
NCBI-GeneID: 103040193
NCBI-ProteinID: XP_007240270
Ensembl: ENSAMXG00000018947
UniProt: A0A8B9LAJ9
Position
16:complement(18746044..18791251)
AA seq 2532 aa
MSNSVASYDQLVRQVEDLRKENSHLRRELEDNSHHLSKLENETSDMKEVLKQLQSKLEQE
ACTLASSGRADVLDQLKELHMDLTNYYELKYQPHNLRAFSETMTSQVGDADDRTPVPPAS
ISRSRSPVCLSSRQSSSVSGEGTAVHPSGHLHPAMGAEGRVTAQHLEDLCKERTMLLSEI
KKEETERRWYYSQLQGLSQRLAELPRIDTFSIQMDLIRQQLEFEAQQLRSVMEERFGTSD
EMVQRTQIRVARLEQLEKELQEAHGSRGPQEKNTQSESQSADCISKASNNPEQDNGAGSS
SMMEAPGEAGSKVEMVFWLLSMLASRDREEMSRTLLAMSSSQESCIAMRKSGCVPLLVQI
LHDGGPGETQGATGCSREARSRASAALHNIVYSQPDEGQARREMRVLHVLEQIRSHCENG
WDWIENHTGTPSPGGTKNDIPEPVDPQICQAMCAIMKLSFEEEYRRAMNELGGLHVIAEL
MQLEQELYGMQNEPMNMALRRYAGMALTNLTYGDVVNKATLCTKKSCLQAIVAQLSSDSE
ELHQVVSSILRNLSWRADINSKRALRDVGSVSGLMACALQATKESTLKSVLSALWNLSAH
STENKVAICSVDGALGFLVSTLTYRCQTNSLAIIESGGGILRNVSSLVATREDYRQVLRD
HNCLQTLLQHLRSHSLTIVSNACGTLWNLSARSPKDQELLWDLGAVSMLRNLIHSKHKMI
AMGSAAALRNLLTNRPLKYKDTAVVSPGSCMPSLYMRKQKALEAELDAKHLAETFDSLEK
QSPKHLNINKPLRHIESLAKDYASDSGCFDDDEAPNVSSSLDTGTFSMLSMFLNNSNFLH
NQPRKRESDPEQDVGPVPTEDKKTQPPEDEVTVAAEKLAKKITNTVAKIDKLVEDITMHT
SSEDSFSLSSEDHFADWNYGPDDLHEARAKSCSPCGLSDTIPFPLKERFSKAHALIRLKT
ANSSLSNDSLNSGSTSDGYCGSKDQIRPSMRPAEQKRPNKLELKVAHEELLNSGATVSKV
ICQNEIPERDSDPAKEIKLPDQGSTDEEKSQEPLVATPATVSTRVSSDTSVPTIKLSPSY
QHVPLIQSVARFGVAKTAIDVQAAQGMRRQAWVPTVMTGGSISKFSVCSARSPTIGQLET
PQKYSVENTPICFSRCSSLSSLSSGDGALDGQSQSENELESDSSLEIIEVEDGDVVRKLD
EDETLEDLSDSQLLMTDQKTCPTSSSTSEPIQIPCSLRHEKTFLRTASPLINEDRSPSSS
SDNYIHETPLVMSRCSSVSSLGSFESPSIASSIQSDPCSEMISGTVSPSDLPDSPGQTMP
PSRSKTPCCAESNGPEQQNLGGVAGQWENSLRKFMEIADFKERFNLPPDLDTMIYFTVEK
PIENFSCASSLSALPLHEHYVQKDVELKLTPLLNQQDNDPDADADDPSCMDQDQYSEGNS
DDDIEILKECINSAMPSRFKKVRPTIMSALNTQSRRSVQLPVYMVLQNNNNQICSGRKVG
MCVKDIHHDDSSYTDSAEGTPMYFSSTTSLSDETLQYPVKMKGSRDWRSRNKETQELIDI
EARRIEELRLFSRFHKSTKMGCNSDIVTNQTNQMNKTMKQMTPTQRLLVQSREMAAKMTQ
QRVQSQSPVRQIQKQGQSLSQSMPHLDFPIRKQGTDLYQNQKTYSRNNTQEKAALQKLRR
PAATEEATYCLYDNEIDIESGMMARVTTRQKQLNDSSKNNPVLHYANPQGRIDNFHRNAL
YRIKQNLIMEEAPPCYSLSSSLSSLSDADFEEHQGKAQRVWLRNKHNLMSNPGQCLPKAQ
HAQSQFEDNSSPSSVSMDSEDDLLLKCITSAMPKQKKKQSNRKRKGEKKQKQKTTQPQKD
SEVWGPGNDQYSDDMASDKDSDLNSVEWRAIQEGANTIITKLQASKSQEPSSESESVLSF
MSGSSFTPKPDINEKKVLKDKKANKPLDFAPRKPVPNLPVVFRGRTVIYTPKKETTLSQR
PPPKKVTPKDAPKNPNLAQHRSRSLHRLGRPNDSTQLSLPKRSSTPPARIPKSSSSGSSQ
SSTPCRQPYKKITSPTQIVKQSPKVASSAPSSPPEKKGCVSPPNQNPKSPPDSKTQKSPV
RIPFMQNPTRQSRAISPLVTNQPTSTNRPNSGTQITGRRILPANRLDLVRMTAAHSRSGE
TDRNGFLRQLTFIKESANVSRQDIPGSRSVPTSKHGSPRRARPGAPAVFLCSSRCQELKP
TAQGPRRLQGLQGQRNGQEQGILKQNMTLSRANSTDRDLTVRRPARRTSSESPCRIPQRN
IPEPKPREKKDDTFKRYSSSPSINVLSRVTSRSSLRSSSSDSSGRAKSEKDIKQKPAQNR
NGSRNSNSKVTWRRIRDEDVPQILKSTLPPTALPLVPSPEGHKPMPPPMPGKLPTITLIS
RKTSDATVQTEDFSANKTNSSTSPTAESGAVLSDEAAKIVLLRKISLTSGNTIQDGDSDG
SLKNYSTASTSTFQSVESSHSGGVGHFRQSCPSKAVRVTPFNYVPSQLSCCSQETQSQAA
TIPEKSGEKLEA
NT seq 7599 nt   +upstreamnt  +downstreamnt
atgtcaaactcggtggcctcctatgaccagctggtgcggcaggtggaggatctccgcaag
gagaactcccacctgcgtcgcgagctggaggacaactcgcaccacctgtccaagctggag
aatgagacctccgacatgaaggaggttctaaagcagcttcagagcaaactggagcaggag
gcctgcactctcgcctcttcagggagagctgatgtgctcgaccagctcaaagagttgcac
atggacttgaccaactattatgagctcaagtaccagcctcacaacctgcgtgcgttctct
gagaccatgaccagtcaggtaggcgacgcggacgacaggacgcctgtgcctccagccagc
atcagcaggtccaggagccctgtctgtttatcgtcccgtcagagctcgtctgtgtccggg
gagggcacggccgtacaccctagcggccacctccacccggccatgggggcagagggccgt
gtcactgctcagcatttagaggatctctgcaaggagaggacgatgctgctgagtgaaatt
aagaaggaggagacagagcggcgttggtattattctcagctgcagggactctcacagagg
ctggctgagttgccccggattgacacattctccattcaaatggaccttattcggcagcag
ttagaatttgaggcccagcagctacgctcggtcatggaggaacggtttggtaccagtgat
gaaatggtacagagaacacagatccgtgtggctcgtctagagcagcttgagaaagagcta
caagaggctcatggttctcgtggtccacaggagaagaacacccaatcagagagtcagagt
gctgactgcatctccaaagcatctaacaaccctgagcaggataatggagctggcagtagc
tctatgatggaggcacccggagaagcagggagcaaagtggagatggtgttctggctgctg
tctatgctggcctccagagatcgggaggagatgtcccgtaccttgttagccatgtccagc
tcgcaggaaagctgcattgcaatgcgcaagtctggctgtgttcccttgctggtgcaaata
ctgcatgacggaggacccggagagactcaaggagccacaggctgtagccgcgaggcgaga
tccagagctagcgctgctctgcacaacattgtgtactcgcagcctgatgagggccaggct
cggcgtgagatgagggtactgcacgtgctggaacagatccgctcacattgtgagaatggt
tgggactggattgagaaccacactggaaccccatcccctggtggtactaagaatgacatc
ccagagccagtagatcctcagatttgccaggccatgtgtgccatcatgaagctttccttt
gaggaggaataccgaagggccatgaacgaacttggtggtcttcatgtcattgcagagctc
atgcagttggaacaggagctgtacggcatgcagaatgaacccatgaatatggccctgcga
agatatgctggcatggcactcaccaatctcacttatggagatgttgtgaataaggccaca
ctttgcacgaagaagagctgccttcaagccattgttgcccagctttcatctgatagtgag
gaattacatcaggtggtctcaagcattcttaggaacctttcatggcgagctgatatcaac
agcaagagagctctccgtgacgttggcagtgtgtcaggactaatggcgtgtgcacttcag
gccacaaaggaatccactttaaaaagtgtgctgagtgctttatggaatttgtcagcacat
agcactgagaataaagtggcgatttgctctgttgatggtgctcttgggtttctggtcagt
acccttacctaccggtgtcaaaccaactcgctggcaatcattgaaagcggtgggggaatt
ctacgcaacgtgtccagccttgttgctaccagagaagattacagacaagtcctcagggat
cacaactgcctccagactttgctacagcacctgcgatctcacagtctaaccattgtgagc
aacgcctgtggaaccctctggaatctgtctgctcgaagtccaaaggaccaagaactacta
tgggacctaggagctgtgagcatgctacgcaatctcatccactcaaagcacaaaatgata
gccatgggaagtgctgcagcgctgaggaacctcctcacaaaccgcccactcaagtataaa
gatactgctgttgtatctccaggctcctgcatgccctcactctatatgaggaaacagaaa
gccttagaggccgaattggatgcaaaacacctggcggaaactttcgattcacttgagaag
caaagccccaagcatttgaatattaacaaacccctacgacacatagagagcctggccaag
gactacgcctcagactctggttgcttcgatgatgacgaggccccgaacgtttcgagtagc
ttagacacaggaacattctccatgctctctatgttcttgaacaactccaacttccttcat
aatcagcctcgcaaacgagagagtgacccagagcaagatgtgggtccggtaccaacagag
gataaaaagacacaacctcctgaagatgaagtgacggttgcggctgaaaagttagccaaa
aagatcaccaacactgtggcgaaaatcgacaagctggtggaagatattaccatgcacact
tcttcggaggacagcttcagtctcagttctgaggaccatttcgcagactggaattatggg
cctgacgatcttcatgaagcacgagccaagtcatgttccccttgtggactttctgatacc
atcccttttcctctgaaagaacgtttcagcaaagctcatgccctcatacgacttaaaaca
gccaactcaagcttgtctaatgacagccttaacagtggcagcactagtgatggctattgt
gggagcaaagaccaaattcgaccttctatgaggccagcagaacagaaacgtccaaacaag
ctcgaacttaaagtcgctcatgaggagctgctcaatagtggtgccactgtttccaaagta
atctgccagaatgagataccggagagagattctgacccagcaaaagaaatcaaattgcca
gatcaaggcagcacagatgaagagaaaagtcaagaacctcttgttgcaacaccggcaact
gtgtcgaccagggtatcttccgatactagcgtaccaaccatcaagctctctccctcctat
cagcatgttccactgatccagagtgttgccaggtttggtgtcgcaaagactgctattgat
gtccaggcagctcagggaatgagaagacaggcctgggtcccaactgtgatgactggcgga
agtattagcaaattctcagtatgctctgcaagaagcccaacaataggccagctggagaca
ccacagaagtattcagtggaaaacacaccaatctgcttctcgcgctgcagttctttgtcc
tccctttcttcaggcgatggggctctcgatggccaaagccaaagtgaaaacgagctggag
agtgactcctctcttgaaattattgaagtggaagatggtgatgtagtgaggaagctagac
gaggatgagacactcgaggatctgagtgacagccagttgcttatgacagaccagaaaacc
tgtcccacaagtagcagtacttctgaacccattcaaattccctgctctttaagacatgaa
aagacattccttagaacagcatcaccgctcataaatgaagacagatccccatccagctcc
tcagacaactacattcacgagacaccacttgtgatgagtcgttgtagctctgtaagttct
ctgggcagctttgagtccccttcaatcgccagttctattcaaagtgatccttgcagtgaa
atgattagcggaactgtgagcccgagtgatctcccagacagcccagggcaaaccatgcca
ccaagtcgcagtaaaacaccatgctgtgctgaatctaatggaccggagcagcagaatctt
ggaggtgttgcaggccaatgggaaaacagcctgcgaaagttcatggaaattgcagacttc
aaggaaaggttcaacttgcccccagacctggacacaatgatctatttcactgttgaaaaa
ccaatcgagaatttttcctgtgcctccagcctgagcgctcttcctctgcatgagcactac
gttcagaaagatgtggaactcaaacttactcctttgctaaatcaacaagacaacgacccg
gatgctgatgccgatgatccatcatgtatggatcaggatcagtacagtgaaggcaactca
gacgatgacattgaaatcctcaaagagtgcatcaactcagccatgccttccagatttaag
aaagtaagacccactataatgtcagccctaaacactcaatctcgaagatctgtgcaatta
ccagtgtacatggtgctccagaataataacaatcagatttgctctggccggaaagtcgga
atgtgtgtgaaggatattcatcatgacgattcttcttacactgattcggctgaaggtact
ccaatgtatttctcgagcaccacttctttaagcgatgagactcttcagtacccagtcaag
atgaaggggtcaagagactggcgctccagaaacaaagagacgcaggaacttattgatata
gaggcgaggagaattgaagaactgcgtctcttctctcgcttccataaatcaacgaaaatg
ggatgcaattctgatatagtaacgaaccaaacaaaccaaatgaacaaaaccatgaaacaa
atgactcctactcaaaggctgcttgtacaaagtagggaaatggcagcgaagatgactcag
caaagagtacaaagccagtcaccagtccgacaaatacagaagcaaggacagagtctgtcg
caaagtatgccgcacttagattttcccatcagaaaacaaggcacagatttgtatcaaaat
cagaagacgtactccagaaataacacacaggaaaaggcagctttgcagaaattgcggcgc
ccagcagccacagaggaagccacctactgcttgtacgacaatgaaattgatatagagagt
ggaatgatggcaagggtaacgacaaggcagaaacagcttaacgattcaagcaagaataac
ccagtgctccactatgcgaacccacaaggtcgcattgacaattttcacaggaacgcactt
tacagaatcaaacaaaacctgattatggaagaagctcccccgtgttactccctcagctca
tctctcagttctctgagtgatgcagattttgaggaacaccaagggaaagctcagcgtgta
tggctgagaaataaacacaatttgatgtccaatccaggtcagtgtctcccaaaagctcaa
cacgctcaaagccagtttgaagataacagctcaccaagttcagtcagcatggactctgag
gatgatcttttattaaaatgcataacatctgctatgccaaagcaaaagaagaaacaatcc
aacagaaaacggaaaggagagaaaaagcaaaaacagaaaacaactcaacctcagaaggac
tcagaagtctggggtcctggaaatgatcagtacagtgatgatatggcatctgataaagat
tccgatcttaacagtgttgaatggagggcgatacaagagggagcgaatacaataatcaca
aagttgcaagcatccaaatcccaggaaccatcatctgaatcagagtcagttctttcattt
atgtctggatcaagctttaccccaaaacctgacatcaatgagaagaaggtactcaaagat
aaaaaggctaataagccacttgattttgccccacgtaaaccagttccaaatttgcctgta
gttttcagaggcagaactgttatatacacacccaagaaagagacaacactttcgcaaaga
ccaccacccaagaaagtgactccaaaggatgctccaaaaaatccaaaccttgctcagcac
cggtccagaagtcttcacagattggggcgccccaatgattctactcaactgtcattaccc
aagagaagctcgactcctcctgccaggatcccaaaaagctcctcttcaggatcatctcaa
agttcaaccccttgcagacagccttacaaaaaaataacatctcctacccaaatagtcaag
caaagtccaaaggtggcaagctcagctccaagtagtccacctgagaagaaaggatgtgtt
tccccaccaaatcaaaaccctaaatcacctcccgacagcaaaactcagaagtcccctgtc
agaataccattcatgcagaatccaacaaggcagtcaagagcaatatcaccattggtgacc
aaccaacctactagtactaacagaccgaatagcggcactcaaataacaggaagaagaatc
ctaccagctaatcgactggatttagttcgcatgacagctgctcattcgcgcagtggtgaa
acagatcgtaatggcttcctcagacagttgacctttattaaagaatcagcaaatgtctca
agacaagacattcctggttcgcgctcagttcctacatccaagcatggatcacctcgaagg
gcacgcccaggagctccagcagttttcctatgttcctctcgctgccaggagctgaagccg
acagcacagggtcccagaagattgcaggggcttcaagggcaaagaaatggacaggagcaa
ggcatcctcaagcagaatatgactctatcaagagcaaattccaccgacagggatctcaca
gtgagacgtcctgccaggagaacaagttcagagagtccctgcaggattccgcagaggaac
atcccagagccgaaaccaagggagaagaaagacgatacgttcaaaagatattcctcctcc
cccagtataaacgtcttaagccgtgtcaccagccgctcctcgctgcgctcctcatcttca
gactcgagtggacgagctaagagtgaaaaggacataaaacagaaaccggcacagaacaga
aacgggtcacgaaacagcaacagcaaagtcacctggaggaggattcgtgacgaggacgtt
ccccagatcttaaagagcactcttccacccaccgcactgcctctggtgccttcccctgaa
gggcacaaaccaatgcctcctcccatgccaggaaaactgccaacaattactctgatctca
cggaaaacaagcgatgcaacagttcaaaccgaggacttctcagccaacaaaaccaattca
agcacgtcccctacagcggagagcggcgcagtgctttcagacgaggcagcaaagatagtt
cttctgagaaaaattagcctgacctctgggaataccattcaagatggagattctgatgga
tccctcaagaattacagcacagcttccacctcaacctttcagtccgtggagagcagccat
agtggaggcgtaggtcacttccgtcagagttgccccagcaaagcagtccgagttacccca
ttcaattatgttcccagccaattgtcatgttgctcccaagaaacacagagtcaagcagca
acaatacctgagaaatcgggggaaaaacttgaggcctag

  All links  
Gene (63)   
   RefGene (59)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (80)   

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