KEGG   Bufo bufo (common toad): 120982179
Entry
120982179         CDS       T07950                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf00562  Inositol phosphate metabolism
bbuf01100  Metabolic pathways
bbuf04020  Calcium signaling pathway
bbuf04070  Phosphatidylinositol signaling system
bbuf04081  Hormone signaling
bbuf04082  Neuroactive ligand signaling
bbuf04261  Adrenergic signaling in cardiomyocytes
bbuf04270  Vascular smooth muscle contraction
bbuf04310  Wnt signaling pathway
bbuf04371  Apelin signaling pathway
bbuf04540  Gap junction
bbuf04621  NOD-like receptor signaling pathway
bbuf04912  GnRH signaling pathway
bbuf04916  Melanogenesis
Module
bbuf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120982179 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    120982179 (PLCB2)
   04371 Apelin signaling pathway
    120982179 (PLCB2)
   04020 Calcium signaling pathway
    120982179 (PLCB2)
   04070 Phosphatidylinositol signaling system
    120982179 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    120982179 (PLCB2)
   04081 Hormone signaling
    120982179 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    120982179 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    120982179 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120982179 (PLCB2)
   04916 Melanogenesis
    120982179 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120982179 (PLCB2)
   04270 Vascular smooth muscle contraction
    120982179 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbuf04131]
    120982179 (PLCB2)
Enzymes [BR:bbuf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120982179 (PLCB2)
Membrane trafficking [BR:bbuf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120982179 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120982179 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 DUF4815
Other DBs
NCBI-GeneID: 120982179
NCBI-ProteinID: XP_040268094
Position
11
AA seq 1236 aa
MSMLSPILSPPEIKSYLSKGERFIKWDDESSTASPVILRVDPKGYYVYWTFQSKEIEFIE
VTSIRDTRFGKYAKIPKSQKLREVFNLDFPENNFLAKTLCIVTGSDMVDLTFHNFVSYKE
NVGKDWATDIMTIITNPILNNASRYSFYEKIHVKLTLQLNADGKIPVRNIFQLFPADRKR
VEQALHSCHLSKGKNDAINPEDFPETVFRTFLMYLCPRPEIDEIFTSHHSKAKPYMTKDH
LTKFINQKQRDSRLNELLFPPAKIEQVQTLIQKYEPSAINKQRGQLSPEGMVWFLCGSEN
SVVSMDKLLVNQDMNQPLTHYFINSSHNTYLTAGQFSGVSSPEMYRQTLLSGCRCVELDC
WKGKPPEEEPIITHGFTMTTEILFKDVIEAIAESAFKTSPCPIILSFENHVDSAKQQAKM
AEYCRTIFGDMLLTDVLEKFPLKAGCPIPSPNDLQGKILIKNKKNQAFLSSEKKAQTNDP
ASAEQGNFLTNENSDNQAEEEAGKEGESDEVVENVNEEEIKQMQSDEGTAGQEATAYEEM
SSLVNYIQPVKFDSFEVSAQKNQSYVISSFVETKAYDLLTKFPVQFVEYNKRQMSRIYPK
GTRMDSSNYMPQMFWNAGCQMVALNFQTMDVAMQHNMGLFEFNGRSGYILKHEFMRRADK
QFDPFTVDRIDVVVANTLSITIISGQFLSDKSVKTYVEVELFGLPGDPKRKYKTKLTSTA
NSLNPVWKEEPFVFEKILMPEMASLRVAAFEEGGKFIGHRIIPVDVIRSGYHHMCLRSES
NMPLTMPSLFVYVEVKDYVPDTWAELTHALSNPIKAFKAQEKSIKINNKTSDEKTIKLHS
NGSCGSIKLPSALLQNCTPRKGSANCAKTDPMNEAAEPETTNQDELQKQKSFIKLQKKHE
KELKELERKGMKRREEILQKYSGAFSDLHTQMNKKKTSKKANKNPEDDYGSVWGAGGMPG
KPDPKVVDLKEKLEEELMRLGEELYESIWKKKEQHSMEQISKLMELAQEKQAAELKVLKD
STDSDTKQMKKKLEMKRLERLEAMSKNTMDKAAQERLKKEINNSHIQEVVQVLQMVSDKW
SNQQQKLEERQTEGLQRIKEQGEQTQKDLQLEYQEKVKSLELEIPTLVHDCIAPCFPSEA
KSLKKEPENCPNRWEFLFAKHDKVESPTVTEEESKTQNDPPANEVEAGTLGSSPATEPLS
TADSVGEISTNEASSSDAPTSSDVAEKISSEEVSTQ
NT seq 3711 nt   +upstreamnt  +downstreamnt
atgtccatgctatcacctatcctgagtccaccggagatcaaaagttacttgtccaagggg
gaacgcttcataaaatgggatgatgaatcatctacagcatctccagtcattctacgtgtt
gacccaaaaggttattatgtgtactggactttccagagcaaggaaattgaatttatcgaa
gtgaccagtatccgagacacgcgattcggaaaatatgccaaaatcccaaagagtcagaaa
ttacgagaagtcttcaacctggactttcctgaaaataatttcctggccaaaaccctttgc
atcgtcactgggtcagacatggtggatctcacctttcataactttgtatcctacaaggag
aacgtcggaaaggactgggctactgacatcatgaccatcatcacaaatcctattctgaac
aacgcttcccgttattccttctatgagaaaatacatgtaaaactcacacttcaattaaat
gcagacggaaagattcctgtacgcaatattttccagctgtttcctgccgacaggaagaga
gtagaacaagcattacactcttgtcatctttcaaaggggaaaaatgatgccatcaaccca
gaggacttccctgaaaccgtcttcagaacgttcctgatgtatctgtgtccacggccagag
atagatgaaatcttcacttcccaccattctaaagccaaaccttacatgactaaagatcac
ctcaccaagtttatcaaccaaaagcaaagagacagtcgcttaaatgagctgctcttccct
cctgcaaagattgagcaagtgcaaactctcatacaaaaatatgagcccagtgccatcaac
aaacagagagggcagctgtctccggaaggtatggtttggttcctctgtgggtctgagaac
agtgttgtgtcaatggacaagttacttgtgaatcaggacatgaatcaacctcttactcac
tattttatcaactcctctcacaacacttacctcacagctggtcagttttctggggtctca
tcccctgaaatgtaccgacagactctgctctctggttgccgctgtgtggagctagactgc
tggaaggggaagcctcctgaggaagaacccattatcactcatggatttacaatgactaca
gagatcctttttaaggatgtcattgaagctattgcggaatcggcattcaaaacctctcct
tgtcccatcatcttgtcatttgaaaaccatgtagactctgccaagcagcaggcaaaaatg
gccgagtactgcagaacaatatttggagacatgttactgactgatgttctagaaaaattt
ccattgaaagcaggatgtccaataccaagtcccaatgatttgcaaggcaaaatcctgata
aaaaacaagaagaaccaggcttttttatcttcagagaagaaagcccaaaccaatgaccca
gcaagtgcagaacagggaaattttctgacaaatgaaaactcagataatcaagcagaagag
gaggcagggaaagaaggtgaaagtgatgaagttgtagaaaatgtgaatgaagaagaaatt
aaacaaatgcagtcagatgagggcactgctggtcaggaggcaacagcttatgaagagatg
tcaagtttggtcaattacatccagccagtgaaatttgattcatttgaggtgtctgcacaa
aagaatcaaagttatgtaatttcttcattcgtggaaactaaagcctatgatctactgacc
aagttcccagtgcagtttgttgaatacaataagagacaaatgagtaggatttatccaaag
ggaaccaggatggattcatctaactacatgcctcaaatgttctggaatgcaggatgtcag
atggtggcgctcaacttccaaacgatggacgtggcaatgcagcataacatgggtctcttt
gagtttaatggcagaagtgggtacatactaaaacatgaattcatgaggcgtgcagacaag
caatttgatccctttacagttgaccgtattgatgtggttgtggctaacacactttcaatt
acaataatttcaggtcagttcctcagcgacaaaagtgtgaaaacctatgtagaagttgag
ttgtttggactgcctggagatcctaagcgaaagtacaaaaccaaattaacctctactgcc
aattcattaaatcctgtatggaaagaagagccatttgtctttgaaaagatcctaatgccg
gagatggcatctctaagagttgcagcttttgaagagggaggaaaattcattggtcatcgg
atcattcctgttgatgtgattagatcaggttaccatcatatgtgtctacggagtgaaagt
aacatgccgcttacaatgccatctctgtttgtctatgtggaggtgaaagactatgtgcca
gatacatgggcagaacttactcacgctctctcaaatcccatcaaagctttcaaagcccag
gagaagtcaataaagataaataacaagacatctgatgagaaaacaatcaagctccactcc
aacggctcgtgtggctctattaaactgccgagcgccttactgcagaactgtaccccacgt
aaaggttcagcaaactgtgcgaaaacggatcctatgaatgaagcagcagaaccagaaacc
acaaatcaggatgaattacaaaaacagaaaagttttataaaacttcagaagaagcatgag
aaagagttaaaggaactggagcgcaaaggaatgaagcgaagggaagagattcttcaaaag
tattctggtgccttcagtgacttgcatacccagatgaacaagaagaagaccagcaagaaa
gccaacaaaaatccagaggatgactacggctcagtgtggggagctggtggaatgccaggt
aaaccagatcctaaggttgttgacttgaaagagaagctagaagaggaactgatgcgcctt
ggagaggagctgtatgagagtatctggaagaagaaagagcagcattccatggagcaaatc
tccaaactaatggagctggcgcaagaaaagcaagcagcagaactaaaagtcctgaaggac
tcaacagacagtgacactaaacagatgaagaaaaagctggagatgaagaggctggaaaga
cttgaagccatgagcaagaatacaatggataaagctgctcaggagaggttaaaaaaggag
ataaacaactctcatattcaagaagtggtgcaggtcctacaaatggtatctgataaatgg
agcaaccagcaacagaaattagaagaaaggcagactgaaggactgcaaagaatcaaagag
caaggagagcaaactcaaaaagaccttcaacttgaataccaggaaaaggtgaagagcttg
gagctggaaataccaactctggttcacgactgcatagcaccatgctttccctcagaagcc
aaatctttgaaaaaagagccagaaaactgtccaaacaggtgggaatttctatttgcaaaa
cacgacaaagtagaatctcccaccgttactgaagaggagtcaaaaacccagaatgaccca
cctgcaaatgaggtagaagctggaactttgggcagcagcccggctacagaaccactttcc
acagccgattcagtgggtgagatatctacaaatgaggcctcatcgagtgacgctccaaca
tcttcagacgtagcggaaaagatttcctcagaggaagtatccacacaatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (12)   

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