KEGG   Bufo bufo (common toad): 120998986
Entry
120998986         CDS       T07950                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf00562  Inositol phosphate metabolism
bbuf01100  Metabolic pathways
bbuf04020  Calcium signaling pathway
bbuf04070  Phosphatidylinositol signaling system
bbuf04081  Hormone signaling
bbuf04082  Neuroactive ligand signaling
bbuf04261  Adrenergic signaling in cardiomyocytes
bbuf04270  Vascular smooth muscle contraction
bbuf04310  Wnt signaling pathway
bbuf04371  Apelin signaling pathway
bbuf04540  Gap junction
bbuf04621  NOD-like receptor signaling pathway
bbuf04912  GnRH signaling pathway
bbuf04916  Melanogenesis
Module
bbuf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120998986 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    120998986 (PLCB1)
   04371 Apelin signaling pathway
    120998986 (PLCB1)
   04020 Calcium signaling pathway
    120998986 (PLCB1)
   04070 Phosphatidylinositol signaling system
    120998986 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    120998986 (PLCB1)
   04081 Hormone signaling
    120998986 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    120998986 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    120998986 (PLCB1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120998986 (PLCB1)
   04916 Melanogenesis
    120998986 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120998986 (PLCB1)
   04270 Vascular smooth muscle contraction
    120998986 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbuf04131]
    120998986 (PLCB1)
Enzymes [BR:bbuf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120998986 (PLCB1)
Membrane trafficking [BR:bbuf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120998986 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120998986 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like RecC_4th
Other DBs
NCBI-GeneID: 120998986
NCBI-ProteinID: XP_040285796
Position
4
AA seq 1225 aa
MAGAQPGVHALQLKRVCVSDTLKRGSKCIKWDDDSNLVYPVVLKMDPNGFFLHWVDQNKE
TELLDISLVKDARWGKHARTPKDPKLKEQLEVGNFGGRLEYRMFTIVYGPDLVNISYLNL
VAFQEEIAKEWTDEIFSLATNLLAQNMSRDAFLEKAYTKLKLQANQEGKIPVKNIYRIFS
ADRKRVETALESCNLPSGRSDSIPQDDFTPELYRVFLNNLCPRPEIDNIFSEIGTKSKPY
LTVDQMTEFINSKQRDPRLNEILYPPLKQEQVQLLIEKYEPSSSLASKGQLSVEGFIRYL
NGEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLAGCRC
VELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPYPILLSFENHVDSPK
QQAKMAEYCKQIFGDGLLTEPLEKFQLEPGVPLPSPMELKYKILVKNKKKSHKSADGSGK
KKLLEQASNACSDSSSVFEPSSPGAGEADIESEEDDDDDEDDCKKSSMEEGTAGNEASAT
EEMSNLVNYIQPVKFESFETSKKRNKSYEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRI
YPKGTRVDSSNYMPQVFWNAGCQMVALNFQTIDFPMQLNMGMYEYNAKCGYRLKPEFMRR
PDKHFDPFTETTVDGIVANTVSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKT
SQGNAVNPVWEEEPIVFKKVVLPSLACLRISAYEEGGKFIGHRILPVYAIRPGYHYICLR
NEKNVPLTLPAIFVCIEVKDYVPDTFADVIEALSNPIKYVNLMEQRSRQLAALTLEDEEE
VKKEAEAGDAPSETNSEPRPAPAENGLNHASTLTPKPASQSVHSQPAPGSVKVPAKTAPA
EDLIMSVLTEVEAQTIDELKQQKSFVKLQKKHYKEMKDLVKKHHKKTTDLIKEHTTKYNE
IQNDYLRRRAILEKTARRDSKKKGESGSPDHNSSTVEQDLAALDAEMAQKLVELKEQQQQ
QLLNLRQEQYYSEKYQKREHIKQLIQKLTDVAEECQNNQLKKLKETCEKEKKELKKKMDK
KRQEKVTETKSKDKNQMEEEKTEMIRSYIQEVVQCLKRLEDAQTKRQEKLIEKHKEIRQQ
ILDEKPKVELDQEYQDKFKRLPMEIQEFVQEAMKGKFSEEREHSSSLLTPDSGKSPVGNS
GNHKSLDHEEEGEEEAPAKAFDTSL
NT seq 3678 nt   +upstreamnt  +downstreamnt
atggcaggggcacagccaggggtacatgctctgcagctcaaacgtgtctgcgtctctgac
accctgaaaagaggatccaagtgcattaaatgggatgatgactcgaatcttgtgtatcct
gttgttctcaaaatggatcctaatggatttttcctgcactgggtggatcagaacaaggag
actgaacttttggatataagtttggttaaagatgccagatggggaaagcatgcacgaact
ccaaaggacccaaagctgaaagagcagttggaagtcggaaactttggaggtcgattagaa
tatcggatgtttaccattgtgtatggcccagatctggttaacatttcatatctgaattta
gtagcatttcaagaagaaattgcaaaggaatggacagatgagattttcagtctggcaaca
aatttgttggcacagaacatgtcccgggatgcatttctggaaaaagcatacaccaagctg
aagcttcaagccaatcaagaagggaaaattcctgttaaaaacatataccgtatattctcc
gcagacagaaaacgagtggaaactgcattagagtcttgcaatcttccatctggcagaagt
gattccatccctcaagatgacttcacaccagaattgtacagagtcttcttaaataacctg
tgtccccgacctgagatagacaacattttctcagagatcggcacaaaaagtaaaccatac
ctcactgttgaccagatgacagaattcattaactccaagcagcgggatccaaggctaaat
gaaattctgtatccacctctgaagcaggaacaagtccagctgctaattgagaaatatgag
cctagcagcagcttggcatcaaaaggtcagctttcagttgaaggattcatacgatatctc
aatggagaagaaaatggagttgttccacctgagaaactggatttaaatgaagatatgtct
caacccctctctcattattttattaattcctcacacaacacttacctcacagctgggcag
ctggcaggtaactcctcggttgagatgtatcgtcaagtgctgttagctggatgccgttgt
gtagaattggattgctggaaggggcgtaccgcagaggaagagccggtgatcacacatggg
tttaccatgaccactgaaatatcttttaaggaagtaatagaagcaattgctgaatgtgca
tttaagacctcaccgtacccgatcctcctgtcctttgaaaatcacgtggactcgccaaaa
caacaggccaagatggctgaatactgcaagcaaatttttggggatggacttttaacagaa
ccattggagaagtttcaacttgaaccaggggtccctcttcctagtcctatggaactgaag
tataaaattcttgtgaaaaataaaaagaaatcgcacaaatcagctgatggaagtggaaag
aagaaactcttagaacaagcgtccaatgcttgcagcgactcttctagtgtatttgagcca
tcatcgcctggcgcaggtgaagccgacattgagagtgaggaagatgatgatgatgatgag
gatgactgtaagaaatcttccatggaagaaggcaccgctggaaatgaagccagtgccaca
gaggagatgtccaacctggtgaactatattcagccggtgaagtttgagtcttttgagact
tctaaaaagagaaacaagagctatgaaatgtcctcctttgtggaaaccaaggggcttgag
cagctgacaaaatctcccgtagagtttgtcgaatataacaaaatgcagcttagtagaatt
tatccaaaaggaacccgagtagattcatccaactacatgcctcaggtcttttggaatgcg
ggatgtcaaatggtagctcttaacttccaaacaatagattttcctatgcaacttaatatg
gggatgtatgaatataatgctaaatgtggatacagactgaagcctgagtttatgagaagg
ccagataaacattttgatccttttactgagacaacagtagatgggatagttgcaaacaca
gtgtctgtaaagatcatttcaggacagtttttgtcggataagaaggttggcacctatgta
gaagtggatatgttcgggttgccagttgataccagaagaaaagcgttcaaaacaaagaca
tcacaaggcaatgcggtgaatcccgtatgggaggaggagcctattgtttttaaaaaggtt
gtgcttccgtcccttgcatgtctaagaatatcggcatatgaagaaggagggaaattcata
ggtcaccggatattacctgtttatgcaatccgtccaggttatcactatatctgcctgaga
aatgagaaaaatgtgccactcactctaccagcaatctttgtctgcatagaagtgaaggat
tacgtccccgacacattcgcagatgtgattgaagctttgtcaaatccaattaaatatgtc
aatttgatggaacaaagatccagacagctggctgcactcacgctggaagacgaagaagaa
gtgaagaaagaggcagaagccggtgatgctccatcagaaactaacagtgaaccaaggccg
gcaccagcagaaaatggcctgaaccatgcttctacactaacaccgaagccagcatcccag
tctgttcacagtcagccagctccaggttctgtaaaagttcctgctaaaactgcacctgct
gaggacctcataatgagtgttttaacagaagtggaagctcagaccatcgacgaactgaaa
cagcaaaagtcctttgttaaattgcagaagaaacattacaaggaaatgaaggatcttgta
aaaaagcaccataagaaaaccactgaccttatcaaggagcacaccacaaagtataatgaa
attcaaaacgattacttaaggaggcgggcaatcctggagaagacagccagaagagacagc
aaaaaaaagggcgaatctgggagtccggatcataattcctctactgtagaacaagattta
gccgcattagatgcagaaatggcacagaaattagtagagctgaaagaacagcagcaacag
cagcttctcaatctccgacaagaacagtattacagcgagaaatatcagaaaagagagcat
atcaaacagctcatccagaagctgacagatgtggccgaggagtgccagaacaaccagctg
aaaaagctcaaggaaacatgtgaaaaagaaaagaaagagttaaaaaagaagatggacaag
aaacggcaagaaaaagtcacagaaaccaaatcaaaagataagaatcaaatggaggaggag
aagacagaaatgatcagatcctatatccaggaagtggtgcagtgccttaaaaggttagaa
gatgctcaaaccaaaaggcaggaaaaacttatagagaaacacaaggagattcgacagcaa
atattggacgaaaagccaaaggttgaacttgatcaggaataccaggacaaattcaaacga
cttccaatggaaattcaagagtttgtccaggaggccatgaagggaaaattcagtgaagaa
agagaacatagctcttctctcctaacacccgacagtgggaagtctccagtggggaactcg
ggaaatcacaaaagtctggatcatgaagaagaaggtgaagaagaggctccagcaaaggca
tttgatacatcgctttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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