KEGG   Bos javanicus (banteng): 133241372
Entry
133241372         CDS       T11659                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
bjv  Bos javanicus (banteng)
Pathway
bjv00562  Inositol phosphate metabolism
bjv01100  Metabolic pathways
bjv04015  Rap1 signaling pathway
bjv04020  Calcium signaling pathway
bjv04022  cGMP-PKG signaling pathway
bjv04062  Chemokine signaling pathway
bjv04070  Phosphatidylinositol signaling system
bjv04071  Sphingolipid signaling pathway
bjv04072  Phospholipase D signaling pathway
bjv04081  Hormone signaling
bjv04082  Neuroactive ligand signaling
bjv04261  Adrenergic signaling in cardiomyocytes
bjv04270  Vascular smooth muscle contraction
bjv04310  Wnt signaling pathway
bjv04371  Apelin signaling pathway
bjv04540  Gap junction
bjv04611  Platelet activation
bjv04613  Neutrophil extracellular trap formation
bjv04621  NOD-like receptor signaling pathway
bjv04713  Circadian entrainment
bjv04720  Long-term potentiation
bjv04723  Retrograde endocannabinoid signaling
bjv04724  Glutamatergic synapse
bjv04725  Cholinergic synapse
bjv04726  Serotonergic synapse
bjv04728  Dopaminergic synapse
bjv04730  Long-term depression
bjv04742  Taste transduction
bjv04750  Inflammatory mediator regulation of TRP channels
bjv04911  Insulin secretion
bjv04912  GnRH signaling pathway
bjv04915  Estrogen signaling pathway
bjv04916  Melanogenesis
bjv04918  Thyroid hormone synthesis
bjv04919  Thyroid hormone signaling pathway
bjv04921  Oxytocin signaling pathway
bjv04922  Glucagon signaling pathway
bjv04924  Renin secretion
bjv04925  Aldosterone synthesis and secretion
bjv04926  Relaxin signaling pathway
bjv04927  Cortisol synthesis and secretion
bjv04928  Parathyroid hormone synthesis, secretion and action
bjv04929  GnRH secretion
bjv04933  AGE-RAGE signaling pathway in diabetic complications
bjv04934  Cushing syndrome
bjv04935  Growth hormone synthesis, secretion and action
bjv04961  Endocrine and other factor-regulated calcium reabsorption
bjv04970  Salivary secretion
bjv04971  Gastric acid secretion
bjv04972  Pancreatic secretion
bjv04973  Carbohydrate digestion and absorption
bjv05010  Alzheimer disease
bjv05016  Huntington disease
bjv05017  Spinocerebellar ataxia
bjv05022  Pathways of neurodegeneration - multiple diseases
bjv05142  Chagas disease
bjv05143  African trypanosomiasis
bjv05146  Amoebiasis
bjv05163  Human cytomegalovirus infection
bjv05200  Pathways in cancer
bjv05415  Diabetic cardiomyopathy
bjv05417  Lipid and atherosclerosis
Module
bjv_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bjv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    133241372 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    133241372 (PLCB3)
   04310 Wnt signaling pathway
    133241372 (PLCB3)
   04371 Apelin signaling pathway
    133241372 (PLCB3)
   04020 Calcium signaling pathway
    133241372 (PLCB3)
   04070 Phosphatidylinositol signaling system
    133241372 (PLCB3)
   04072 Phospholipase D signaling pathway
    133241372 (PLCB3)
   04071 Sphingolipid signaling pathway
    133241372 (PLCB3)
   04022 cGMP-PKG signaling pathway
    133241372 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    133241372 (PLCB3)
   04081 Hormone signaling
    133241372 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    133241372 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    133241372 (PLCB3)
   04613 Neutrophil extracellular trap formation
    133241372 (PLCB3)
   04621 NOD-like receptor signaling pathway
    133241372 (PLCB3)
   04062 Chemokine signaling pathway
    133241372 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    133241372 (PLCB3)
   04922 Glucagon signaling pathway
    133241372 (PLCB3)
   04929 GnRH secretion
    133241372 (PLCB3)
   04912 GnRH signaling pathway
    133241372 (PLCB3)
   04915 Estrogen signaling pathway
    133241372 (PLCB3)
   04921 Oxytocin signaling pathway
    133241372 (PLCB3)
   04926 Relaxin signaling pathway
    133241372 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    133241372 (PLCB3)
   04918 Thyroid hormone synthesis
    133241372 (PLCB3)
   04919 Thyroid hormone signaling pathway
    133241372 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    133241372 (PLCB3)
   04916 Melanogenesis
    133241372 (PLCB3)
   04924 Renin secretion
    133241372 (PLCB3)
   04925 Aldosterone synthesis and secretion
    133241372 (PLCB3)
   04927 Cortisol synthesis and secretion
    133241372 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    133241372 (PLCB3)
   04270 Vascular smooth muscle contraction
    133241372 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    133241372 (PLCB3)
   04971 Gastric acid secretion
    133241372 (PLCB3)
   04972 Pancreatic secretion
    133241372 (PLCB3)
   04973 Carbohydrate digestion and absorption
    133241372 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    133241372 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    133241372 (PLCB3)
   04725 Cholinergic synapse
    133241372 (PLCB3)
   04728 Dopaminergic synapse
    133241372 (PLCB3)
   04726 Serotonergic synapse
    133241372 (PLCB3)
   04720 Long-term potentiation
    133241372 (PLCB3)
   04730 Long-term depression
    133241372 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    133241372 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    133241372 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    133241372 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    133241372 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    133241372 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    133241372 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    133241372 (PLCB3)
   05142 Chagas disease
    133241372 (PLCB3)
   05143 African trypanosomiasis
    133241372 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    133241372 (PLCB3)
   05016 Huntington disease
    133241372 (PLCB3)
   05017 Spinocerebellar ataxia
    133241372 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    133241372 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    133241372 (PLCB3)
   05415 Diabetic cardiomyopathy
    133241372 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    133241372 (PLCB3)
   04934 Cushing syndrome
    133241372 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bjv04131]
    133241372 (PLCB3)
Enzymes [BR:bjv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     133241372 (PLCB3)
Membrane trafficking [BR:bjv04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    133241372 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    133241372 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 GP24_25
Other DBs
NCBI-GeneID: 133241372
NCBI-ProteinID: XP_061262753
Position
29:42952433..42968748
AA seq 1234 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRLGSGVPDS
SVRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGE
EGLQRGPDVLGPAYREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANAVRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQSGPETSQETQTQQL
GCQLNPHPTPSPLDASPRRPPGPATSPTSSSISSSISSPGQRDDLIASILSEVAPAPLDE
LRGHKALVKLRSRQERDFRELYKKHQRKAVALTRRLLDNLAQARAGSRCRQRPGVLSGED
ERAEEEEVSRYQEFQKKQVQCLLELREAQVDTEADRRLEHLQQAQLKLREVVLDAHMTQL
KKLKEINEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLE
EAQKQRQERLVAGQQQILQQLAEEEPKLLAQLVQDCQEQRERLPQEIRWSLLGETQEGLG
DGHLVACASNGHAPGSSGHLPGADSESQEETTKL
NT seq 3705 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctagagccgcccaccgtcgtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtaaccctgcgagtggactccaatggcttcttcctgtactggacgggacccaacatggag
gtggacacactcgacatcagttccatcagggacaccaggacgggccgttatgcccgcctg
cccaaggaccccaagatccgggaggtgttgggctttgggggccctgatgcccggttggag
gagaagctgatgacagtggtggccgggccagacccggtgaatacaacattcttgaacttc
atggccgtgcaggatgatacagccaaggtctggtccgaggagctcttcaagttggctatg
aacatcctggctcagaacgcctcccggaacaccttcttgcgcaaagcatacacgaagctg
aagctgcaggtaaaccaggatggacggattccagtcaagaacatcctgaagatgttctca
gcagacaagaagcgggtagaaactgcactggaatcctgtggcctcaatttcaaccgaagc
gagtccatccggcctgacgagttttccttggaaatctttgagcggttcctgaacaagctg
tgtctgcggccagacattgacaagatcctgctggagataggtgccaagggcaaaccttac
ctgacgctggagcagctcatggatttcattaaccagaagcagcgagacccgcggctcaac
gaagtgctgtacccacctctgcggccctcccaggcccgactgctcatcgagaagtacgaa
cccaacaagcagttcctggagcgagaccagatgtccatggagggcttcagccgctacctg
ggaggtgaggagaatggcattctgccgcttgaggccttggatctgagcacagacatgacc
cagccgctcagcgcctacttcatcaattcctcgcacaacacctatctcacggcggggcag
ctggccggaacctcgtcggtggagatgtaccggcaggcgctgttgtggggctgccgctgt
gtggagctggacgtgtggaaggggcggccgcccgaggaggagccgttcatcacgcacggc
ttcaccatgaccacggaggtgccgctgagagacgtgcttgaggccatcgcggagactgcc
ttcaagacttcgccctaccccgtcatcctctcctttgagaaccacgtggactcggcgaaa
cagcaggccaagatggctgagtactgccgctccatctttggggacgctctgctcatcgac
cccctggacaagtacccgctggccccaggcgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcggcaccgactcggcagcggcgtccccgacagc
tccgtgcgcaagcggccactggagcagagcaactcggccctgagcgagagctccgccacc
accgagccctcctcgccccagcttgggtcccccagctctgacagctgcccaggcctgagc
aatggggaggaggtgggcctcgagaagcccagcctggagcctcagaagtctctgggggag
gagggtttgcagcggggccctgatgttcttggacctgcctaccgggaggatgaggaagag
gacgaggaagaggaggaacaaacggaccccaaaaagccgaccacggatgagggcaccgcc
agcagtgaggtcaacgccactgaggaaatgtccacactcgtcaactatatcgagcctgtc
aagttcaagtccttcgaggctgctcgaaagaggaacaagtgcttcgagatgtcgtccttc
gtggagaccaaggccatggagcaactgaccaagagccccatggagtttgtggaatacaac
aagcagcagctcagccgcatctaccccaagggcacccgcgtggactcgtccaactacatg
ccccagctcttctggaacgtgggctgccagcttgttgcactcaactttcagaccctggat
gtgccaatgcagctcaacgccggcgtgtttgagtacaacgggcgcagcggctacctactc
aagcctgagttcatgcggcggccggacaagtcctttgaccccttcaccgaagtcatagtg
gacggcatcgtggccaatgccgtgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggaatctacgtggaggtagacatgttcgggcttcctgttgacacgcggcgc
aagtaccgcacacggacctcacaggggaactcgttcaaccctgtgtgggatgaggagcca
ttcgacttccccaaggtggtgctgcccacactggcttcgctgcgcatcgcggcctttgag
gaggggggcaagttcgtggggcaccggatcctgcctgtctctgctatccgctcagggtac
cattacatctgcctgcggaatgaggccaaccagccgctgtgcctgccagccctgctcatc
tacaccgaggcctccgactacatccccgacgaccaccaggactatgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcatt
ggggagagcgaggctcagtctggcccggagacgagccaggagacccagactcagcagctg
gggtgccagctgaacccacacccgacgcccagcccactggacgcctccccgcgccggccc
ccaggccccgccacctccccgaccagctcctccatcagctcctccatcagcagcccaggt
cagcgcgatgatcttatcgccagcatcctctcagaggtggccccggccccgctggacgag
ctccgaggccacaaggccctagtgaagctccggagccggcaagagcgagacttccgggag
ctgtacaagaaacatcagcggaaggccgttgccctcacgcgccggttgctcgacaacctg
gcccaggcccgtgcggggagcaggtgccgacagcggcctggtgtcctaagcggggaggac
gagagggcagaagaggaagaggttagcaggtatcaagagttccagaagaaacaggtgcag
tgtctgctggagctgagggaggcccaggtggacacagaggcggatcggaggctggagcac
ctgcagcaggctcagctgaagctcagggaggttgtcctggacgctcacatgactcagttg
aagaaactgaaggagataaacgagagggagaagaaggagctgcagaagatcctggacagg
aaacgccacaacagcatctcagaggccaagaccagggagaaacataagaaagaggcggaa
ctgacagagattaaccgtcggcacatcactgagtcagtcaactccatccgtcggctggag
gaggcccagaagcagcggcaggaacgccttgtggccggacagcagcagatcctccaacag
ctggcggaagaggagcccaagctgctggcccagctggtccaggactgtcaggagcagcgg
gagaggctgccccaggagatccgctggagcctgctgggcgagacacaggagggactgggg
gacgggcatctggtcgcctgtgccagcaacggtcacgcgcctgggagcagcgggcacctg
cccggcgctgactcagagagccaggaggagactacaaagctctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (14)   

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