KEGG   Balaenoptera musculus (blue whale): 118892175
Entry
118892175         CDS       T09887                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus04310  Wnt signaling pathway
bmus04390  Hippo signaling pathway
bmus04519  Cadherin signaling
bmus04550  Signaling pathways regulating pluripotency of stem cells
bmus04810  Regulation of actin cytoskeleton
bmus04934  Cushing syndrome
bmus05010  Alzheimer disease
bmus05022  Pathways of neurodegeneration - multiple diseases
bmus05165  Human papillomavirus infection
bmus05200  Pathways in cancer
bmus05206  MicroRNAs in cancer
bmus05210  Colorectal cancer
bmus05213  Endometrial cancer
bmus05217  Basal cell carcinoma
bmus05224  Breast cancer
bmus05225  Hepatocellular carcinoma
bmus05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    118892175 (APC2)
   04390 Hippo signaling pathway
    118892175 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    118892175 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118892175 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118892175 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118892175 (APC2)
   05206 MicroRNAs in cancer
    118892175 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118892175 (APC2)
   05225 Hepatocellular carcinoma
    118892175 (APC2)
   05226 Gastric cancer
    118892175 (APC2)
   05217 Basal cell carcinoma
    118892175 (APC2)
   05213 Endometrial cancer
    118892175 (APC2)
   05224 Breast cancer
    118892175 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    118892175 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118892175 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    118892175 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118892175 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bmus01009]
    118892175 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:bmus03036]
    118892175 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:bmus04812]
    118892175 (APC2)
Protein phosphatases and associated proteins [BR:bmus01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     118892175 (APC2)
Chromosome and associated proteins [BR:bmus03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    118892175 (APC2)
Cytoskeleton proteins [BR:bmus04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     118892175 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC APC_r Arm Suppressor_APC Arm_APC_u3 SAMP ZER1-like_2nd ARM_PUB SSNA1 Sec7-like_HUS bZIP_1 MPS2 Wtap PDC10_C Par-4_C HALZ CCDC138_cc
Other DBs
NCBI-GeneID: 118892175
NCBI-ProteinID: XP_036702345
UniProt: A0A8B8X2L3
Position
3:complement(170422087..170447952)
AA seq 2277 aa
MGLLGLLSLLHSAFFGDQALQELKMTSSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYSLKFQPPAL
APEPTARTPEGSPVHSSGPSKDSFGELSRATIQLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLSAQDRVQQTEPQALLAVKSMPMDEDPEAEVPTHPEDGAPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGAGGRNGTPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPE
GGGAGGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRD
PLNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAIVAQLASESEELHQVVSSILRNL
SWRADISSKKVLREVGSMTALMQCVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSAGDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPAKYQAAATAVSPGACAPSLYVRKQRALEAALDARHLAQALDHLEKQGLPEAEAASKK
PLPPLRHLDGLAQDYASDSGCFDDDDAPSLATAAAATAEPASPAVLPLFLGSPFLQGQAL
ARTPPARRGGLESEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSS
GDPGQEAPREGRAHSCSPCRGPEAGRREAGGRAHPLLRLKAAHASLSNDSLNSGSTSDGH
CPREHSRPYPLAALAEHCEGPLCGQARPSRLDLNLPSGQVEPKARDAAATDARVCTIKLS
PTYKHVPLLEGTARAGAGSLAPRARKQAWLPAEDLNKVPEKLAAEKAPLCLSRCSSLSSL
SSAGRPGPSEAGDLDDSDSSLEGLEEAGPSEAGLDGAWQGPGAASLPMAIPVPQRGRGLG
VEDATPSSSSENCVQETPLVLSRCSSVSSLGSFESPSIASSVASDPCSGLGSGTVSPSEL
PDSPGQTMPPSRSKTPPPAPAPPGEREATQFSLQWESYVKRFLDIADCRERCRLPSELDA
GSVRFTVEKPDENFSCASSLSALALHELYVQKDVELRLLPPACPERSSGGGVGPGHRRRD
EAGGRLEGPTSTDRDLELLRECLGGAVPARLRKVASALVPGRRTLPVPVYMLVPAPARED
ESCTDSAEGTPVTFSSATSLSEETLQGPPGDGGPAQGQKAAGRAAPTRQPAGHRHRAGGT
GRSTEQPRGAGRSRAGLELPLCRPPSACRDRDSSRPGRARGDGALQSLCLTTPTEEAVYC
FYGNDSDEEPSAAAAVAPPRRASAIPRAVKRESLAGGRKEVQAVPKVAPPKVAAPKVTPP
KVAAPKVAPPARGQPSLIADETPPCYSLSSSASSLSEPEPFDRTASRSRAREPGVTKDPG
PGGRRDGAPRPRAEAELLRRCTGSAVPRRRPQVSGPGCRQSRAAQQQKRPAEGPREHSEE
AAGSDHASDLDSVEWRAIQEGANSIVTWLHQAAAAATREASSESDSVLSFASGQSVGSTL
QPPLHRKGRRPRAEGQAGSAMRPEKRDRALAQRSGDLEKPRGTQATSGVPAVLRGRTVIY
MPSPATRAQPKGAPGPRNVPRKTGAPNPVQPAAPAKTSGPGQQRSRSLHRPGKISELAAL
SPPQRSATPPARLAKTPSSSSSQTSPASQPLTRRSPPAVQAAGPLPGPGASPATKTPARA
LLAKQHKTQKSPVRIPFMQRPARRGPPPLARAAPEPGPRARGGRPGLPRVASARSSGSEA
SDRSGFRRQLTFIKESPGLLRRRRSELSAAEAATPAAQASLPRRGRPALPAVFLCSSRCD
ELRGAPRQAPAPQRPPMARPGPGERLPRRTSSESPSRLPVRTPAARPETVKRYASLPHIS
VARGPDAPAPGPVADNAPCSSTGEAAPGTTWRRIRDEDVPHILRSTLPPRALPLLGSSPE
DGPTGPPQRKTSDAVVQTEDFATAKTNSSTSPSLESWATPQATTGGPPSLLLGSDVDGPG
PAKAPAPGPFVPASRHGSPSRSARVPPFNYVPSPMVAATTDSAVEKAPAPVPTGLLG
NT seq 6834 nt   +upstreamnt  +downstreamnt
atggggctcctggggctgctgagcctgctgcactcggccttcttcggggaccaggcgctg
caggagctgaagatgacgagctccgtggcgccctacgaacagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgaggcaggagcttcgggataactcaagccacttg
tccaagctggagacagaaacgtcgggcatgaaggaggtcctgaagcacttgcagggcaag
ctggagcaggaggcccgcgtcctggtgtcctcagggcagaccgaggtgctggagcagctg
aaagccctgcagatggacatcaccagcctgtacagcctcaagttccaacccccggctctg
gcccccgagcccactgcccggacccccgagggaagcccggtgcacagctccgggccctcc
aaggacagctttggggagctgagccgggccaccatccagctgctggaggaactggaccgg
gaacggtgtttcctgttgaatgagattgagaaggaggagaaggagaagctctggtattac
tcgcagctgcaaggcctatccaagcgcctggacgaactccctcacgtggagacgcagttc
tcgatgcagatggatctgatccggcagcagctggagttcgaagcccagcacatccgctcg
ctgatggaggagcgcttcggcacctcggacgagatggtgcagcgggcgcagatccgtgct
tcccgcctggagcagatcgacaaggagttgctgtcggcgcaggaccgggtgcaacagacc
gagccccaggccttgctggcagtgaagtcgatgccgatggatgaggaccccgaggctgag
gtccccacgcaccctgaggatggtgcccctcagccgggcaacagcaaggtggaggtggtc
ttctggctgctgtccatgctggcgacgcgtgaccaggaggacacggcacggacgctgctc
gccatgtccagttcacctgagagctgcgtggccatgcgccgctcgggctgcctgccgctg
ctgctgcagatcctgcacggcaccgaggccggggctgggggtcgcaacgggaccccaggg
gcgccgggagccaaggatgcgcgcatgcgcgccaacgcagcgctgcacaacatcgtcttc
tcccagccggaccagggtctggcgcgcaaggaaatgcgcgtcctgcacgtgctcgagcag
atccgtgcctactgtgagacctgctgggactggctgcaggcccgggacggcgggcccgag
ggcggcggcgccggcggcgccccggtccccatcgagccacagatctgccaggccacctgc
gccgtgatgaagctgtccttcgacgaggaataccgccgcgccatgaacgagctgggtggg
ctgcaggctgtggcggagttactgcaggtcgactatgagatgcacaagatgacccgggac
cctctcaacctggccctgcgccgatacgccggcatgaccctcaccaacctaaccttcggg
gacgtcgccaacaaggccgcactgtgcgcccgccggggctgcatggaggccatcgtggcc
cagctggcgtccgagagtgaggagctgcaccaggtggtgtccagcatcctgcgcaacctg
tcctggagggcggacatcagcagcaagaaggtgctgagggaggtgggcagcatgacggcc
ctgatgcagtgcgtcctgcgagcctccaaggagtccaccctgaagagcgtgctcagcgcc
ctgtggaacctctcggcgcacagcacggagaacaaggccgccatctgccaggtggacggc
gccctgggcttcctggtcagcacactgacctacaagtgccagagcaactcgctggccatc
atcgagagcggcggcggcatcctgcgcaacgtgtccagcctcatcgccacccgcgaggac
tacaggcaggtgctgcgggaccacaactgcctgcagacgctgctgcagcacctgacgtcg
cacagcctgaccatcgtgagcaacgcatgcggcacgctctggaacctgtcggcccgcagc
gccggcgaccaggagctgctgtgggacctgggcgccgtgggcatgctgcgcaacctggtg
cactccaagcacaagatgatcgccatgggcagcgccgccgccctgcgcaacctgctggcc
caccggcccgccaagtaccaggcggcggccaccgccgtctcccccggcgcctgtgcgccc
agcctgtacgtgcgcaagcagcgggcgctggaggctgcgctggacgcgcggcacctggcg
caggcactcgaccacctggagaagcagggcctgcccgaggccgaggccgcctccaagaag
ccgttgccgcccctgcgccacctggacggcctggcccaggactacgcttctgactcgggc
tgcttcgatgatgacgacgcaccctccctggccaccgctgctgccgccaccgccgagcct
gccagccccgccgtgctgcccctcttcctgggcagccccttcctgcagggccaggcgctg
gcccgcaccccccccgcccgccggggcggcctggagtccgagaaggaggccggcggggag
gcagctgtggcagccagggccaaggccaagctggcactggcagtggcgcgcatcgaccgg
ctggtggaggacatctcggccctgcacacctcgtccgacgacagcttcagcctcagctct
ggggatcccgggcaggaggccccgcgggagggccgcgcgcactcctgctccccttgccgg
gggcccgaggcggggcggcgagaggccggcggccgggctcacccgctgctgcggctcaag
gcggcccacgccagcctctccaacgacagtcttaacagcggcagcaccagcgacgggcac
tgtccccgcgagcactcgcggccctacccgctggccgcgctggccgagcattgcgaggga
cccctgtgcggccaggcgcggcccagccggcttgacctcaacctgcccagcggccaggtt
gagcccaaggcccgggacgccgcggccacagatgcccgcgtgtgcaccatcaagctgtcg
cccacctacaagcacgtgccgctgcttgagggcaccgccagggcgggcgcggggtccctg
gcccccagggcccggaaacaggcctggctgcccgcagaggacctgaacaaggtgcccgag
aagctggcggcggagaaggcacccctctgcctgtcgcgctgcagctccctgtcctcactg
tcctcggccggccgcccagggcccagtgaggccggggacctggacgacagcgactcgtcc
ctggaggggctggaggaggccggccccagtgaggccgggctggacggggcctggcagggg
ccgggggccgcctccctgcccatggccatcccggtgcctcagcggggccggggcctgggg
gtggaggacgccacgccgtccagctcgtccgagaactgcgtgcaggagacgccactggtg
ctgagccgctgcagctcggtcagctcgctgggcagcttcgagagcccatccatcgccagc
tccgtcgccagcgacccgtgcagcgggctgggcagcggcacagtcagccccagcgagctt
cctgacagccccgggcagactatgccaccgagccgcagcaagacgcccccgccagccccc
gcgccgccgggcgagcgtgaggccacccagttcagcctgcagtgggagagctacgtgaag
cgcttcctggacatcgccgactgccgggagcgctgccggctgccgtccgagctggacgcg
ggcagcgtgcgcttcactgtggagaagcccgacgagaacttctcatgtgcttccagcctg
agtgcgctggctctgcacgagctctacgtgcagaaggacgtggagctgcggctgctgccc
ccggcctgccccgagcgcagcagtgggggaggcgtgggccccgggcaccgccggcgggac
gaggccggcggccgcctcgaagggccaacatccaccgaccgggacctggagctgctgcgc
gagtgcctgggtggggccgtgcccgcccggctccgcaaggtggcctcggcactggtgcct
ggccgccgcaccctgcctgtgcccgtctacatgctggtgcccgccccagcccgggaggat
gagtcctgcaccgactcggccgagggtacgccagtcacgttctccagcgccacctccctc
agcgaggaaacactgcagggaccccccggggacggcgggcctgcgcaggggcagaaggct
gcaggccgtgccgcccccaccaggcagcccgccgggcaccggcacagggcggggggcacg
ggccggagcacagagcagccccggggggctggcaggagccgcgcagggctcgagctgccc
ctctgccggcccccgagcgcctgcagggacagggacagctcccgcccgggccgggcgcgt
ggggacggggccctgcaatctctgtgcctcacgacgcccaccgaggaggctgtgtactgc
ttctacggcaacgactcagacgaggagccgtccgcggcagcggcggtggcacccccgcgg
cgggcatctgcgatcccccgcgcggtgaagagggaatccctggctggtggcaggaaggag
gtgcaggccgtgcccaaggtcgcgccacccaaggttgctgcgcccaaggtcacgccgccc
aaggttgctgcgcccaaggtcgcgccacccgccaggggccagcccagcctcattgccgat
gagacaccaccatgctactccctgagctcctccgccagctccctgagcgagcctgaaccc
tttgaccgcacggccagccggtcccgagcccgcgagccaggggtcaccaaggacccaggc
cccgggggcaggcgggacggcgccccccgcccgcgggccgaggcagagctgctccggcgc
tgcactggctcagccgtgcccagacgccggccccaggtgtctggcccagggtgccgccag
tcccgagcggcgcagcagcagaagaggccagcagaggggccccgggagcacagtgaggag
gcggcgggctcggaccacgcctcagacctggacagcgttgagtggcgcgccatccaggag
ggggccaactccatcgtcacgtggctacaccaggcggcggcggcggccacccgcgaggcc
tcctctgagtccgactccgtcctgtcctttgcctcagggcagtcggtgggctccaccctg
cagcctcccctgcacaggaaggggcgacggccaagggcagagggccaggcgggcagtgcc
atgcggccagagaaacgggacagggctctggcccagcgcagcggcgacctggagaagcca
cgtggcactcaggccacgtctggggtgccagccgtgctccggggacggacggtgatctac
atgcccagcccagcgacccgggcccagcccaaaggtgcccctgggccccgcaatgtgccg
agaaagacgggagccccaaacccagtgcagccagcagcccccgccaaaacctcaggcccc
gggcagcagcggtctcgaagcctgcaccgacctggcaagatctcagagctggcggcgctg
agcccccctcagaggagcgccacgccacccgcccgcctggccaagaccccctcgtcgagc
tcctcccagacctccccggcctcccagcctctgacgaggaggtcacccccggccgtccag
gctgcaggacccctgcctggccccggggcctcccccgcaaccaagactcccgcccgggcc
ctgctggccaagcagcacaagacacagaagtcgcccgtgcggatccccttcatgcagagg
cccgccaggcgggggccgccacccctggccagggcagccccggagccaggtccaagggcc
cgagggggccgcccggggctgcctcgtgtggcctccgcccgctccagcggcagcgaggcc
tccgaccgctccggtttccggcggcagctgaccttcatcaaggagtcgccgggcctgctg
cgccgccgacgctccgaactgtccgccgccgaggccgccaccccggctgcccaggccagc
ctgccccgccgtggccggcccgcgctacctgccgtcttcctatgctcctcgcgctgtgat
gagctgcggggggccccccggcaggctccggccccccagcggccccccatggcccggccc
ggcccgggcgagcggctgccccggcgcaccagctctgagagcccgtctcgcctgccggtc
cgcacgccggccgcgcggcccgagacggtcaagcgctacgcctccctgcctcacatcagt
gtggcccgcgggcccgacgcccccgcccctgggcctgtggcggacaacgcgccctgcagc
agcactggggaggccgcgccgggcaccacgtggcgtcgcatccgggacgaggacgtcccg
cacatcctgcggagcacgctgcccccccgcgccctgcccctgctgggctcctcacccgag
gacggccccacaggccctccgcagcgcaagaccagcgacgccgtggtccagaccgaggac
ttcgcgactgccaagaccaactcgagcacgtccccgagcctggagagctgggcgacccca
caggccacgaccggcggccccccctccctcctcctcggcagcgacgtggacgggccgggc
cccgccaaggcgcccgcccccggccccttcgtccccgccagccgacacggctcccccagc
cgctccgcccgcgtcccccccttcaactacgtgcccagccccatggtggcagccaccact
gactctgccgtggagaaagcccccgcccccgtccctaccggcctcctgggatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (19)   
   Pfam (19)   
All databases (28)   

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