KEGG   PATHWAY: bsu00620
Entry
bsu00620                    Pathway                                

Name
Pyruvate metabolism - Bacillus subtilis subsp. subtilis 168
Class
Metabolism; Carbohydrate metabolism
Pathway map
bsu00620  Pyruvate metabolism
bsu00620

Module
bsu_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bsu00620]
bsu_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bsu00620]
Other DBs
GO: 0006090
Organism
Bacillus subtilis subsp. subtilis 168 [GN:bsu]
Gene
BSU29680  acsA; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BSU29560  ytcI; acyl--CoA ligase [KO:K01895] [EC:6.2.1.1]
BSU14580  pdhA; pyruvate dehydrogenase E1 component subunit alpha [KO:K00161] [EC:1.2.4.1]
BSU14590  pdhB; pyruvate dehydrogenase E1 component subunit beta [KO:K00162] [EC:1.2.4.1]
BSU08080  acoC; dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system [KO:K00627] [EC:2.3.1.12]
BSU14600  pdhC; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [KO:K00627] [EC:2.3.1.12]
BSU14610  pdhD; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BSU24060  lpdV; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BSU08090  acoL; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BSU26970  adhB; zinc-type alcohol dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
BSU27010  adhA; formaldehyde dehydrogenase AdhA [KO:K13979] [EC:1.1.1.2]
BSU29470  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
BSU37660  eutD; phosphate acetyltransferase [KO:K00625] [EC:2.3.1.8]
BSU29180  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
BSU29200  accA; acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
BSU24350  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K02160]
BSU24340  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
BSU18240  yngH; biotin carboxylase 2 [KO:K01961] [EC:6.4.1.2 6.3.4.14]
BSU29210  accD; acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
BSU07640  yflL; acylphosphatase [KO:K01512] [EC:3.6.1.7]
BSU39860  aldX; aldehyde dehydrogenase AldX [KO:K00128] [EC:1.2.1.3]
BSU38830  aldY; aldehyde dehydrogenase AldY [KO:K00128] [EC:1.2.1.3]
BSU19310  dhaS; aldehyde dehydrogenase DhaS [KO:K00128] [EC:1.2.1.3]
BSU37960  ywdH; aldehyde dehydrogenase YwdH [KO:K00128] [EC:1.2.1.3]
BSU04340  ydaP; thiamine pyrophosphate-containing protein YdaP [KO:K00158] [EC:1.2.3.3]
BSU03050  ldh; L-lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
BSU33400  yvgN; glyoxal reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
BSU29050  ytbE; oxidoreductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
BSU40860  yyaH; hypothetical protein [KO:K01759] [EC:4.4.1.5]
BSU38370  ywbC; hypothetical protein [KO:K01759] [EC:4.4.1.5]
BSU28700  ysfE; hypothetical protein [KO:K01759] [EC:4.4.1.5]
BSU24790  yqgX; hypothetical protein [KO:K01069] [EC:3.1.2.6]
BSU34680  yvcT; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BSU23550  mleA; NAD-dependent malic enzyme 1 [KO:K00027] [EC:1.1.1.38]
BSU29220  ytsJ; NAD-dependent malic enzyme 4 [KO:K00027] [EC:1.1.1.38]
BSU37050  ywkA; NAD-dependent malic enzyme 2 [KO:K00027] [EC:1.1.1.38]
BSU29880  malS; NAD-dependent malic enzyme 3 [KO:K00027] [EC:1.1.1.38]
BSU14860  pycA; pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
BSU29120  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BSU33040  fumC; fumarate hydratase class II [KO:K01679] [EC:4.2.1.2]
BSU30560  pckA; phosphoenolpyruvate carboxykinase [KO:K01610] [EC:4.1.1.49]
BSU35190  yvkC; phosphotransferase YvkC [KO:K01007] [EC:2.7.9.2]
BSU24170  mmgA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BSU10350  yhfS; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BSU28280  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
bsu00010  Glycolysis / Gluconeogenesis
bsu00020  Citrate cycle (TCA cycle)
bsu00061  Fatty acid biosynthesis
bsu00260  Glycine, serine and threonine metabolism
bsu00290  Valine, leucine and isoleucine biosynthesis
bsu00300  Lysine biosynthesis
bsu00630  Glyoxylate and dicarboxylate metabolism
bsu00640  Propanoate metabolism
bsu00650  Butanoate metabolism
bsu00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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