KEGG   Bos taurus (cow): 112446776
Entry
112446776         CDS       T01008                                 
Symbol
EP300
Name
(RefSeq) histone acetyltransferase p300
  KO
K04498  E1A/CREB-binding protein [EC:2.3.1.48]
Organism
bta  Bos taurus (cow)
Pathway
bta03083  Polycomb repressive complex
bta03250  Viral life cycle - HIV-1
bta04024  cAMP signaling pathway
bta04066  HIF-1 signaling pathway
bta04068  FoxO signaling pathway
bta04110  Cell cycle
bta04310  Wnt signaling pathway
bta04330  Notch signaling pathway
bta04350  TGF-beta signaling pathway
bta04519  Cadherin signaling
bta04520  Adherens junction
bta04630  JAK-STAT signaling pathway
bta04720  Long-term potentiation
bta04916  Melanogenesis
bta04919  Thyroid hormone signaling pathway
bta04922  Glucagon signaling pathway
bta04935  Growth hormone synthesis, secretion and action
bta05016  Huntington disease
bta05152  Tuberculosis
bta05161  Hepatitis B
bta05164  Influenza A
bta05165  Human papillomavirus infection
bta05166  Human T-cell leukemia virus 1 infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05200  Pathways in cancer
bta05203  Viral carcinogenesis
bta05206  MicroRNAs in cancer
bta05211  Renal cell carcinoma
bta05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    112446776 (EP300)
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    112446776 (EP300)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    112446776 (EP300)
   04330 Notch signaling pathway
    112446776 (EP300)
   04350 TGF-beta signaling pathway
    112446776 (EP300)
   04630 JAK-STAT signaling pathway
    112446776 (EP300)
   04066 HIF-1 signaling pathway
    112446776 (EP300)
   04068 FoxO signaling pathway
    112446776 (EP300)
   04024 cAMP signaling pathway
    112446776 (EP300)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    112446776 (EP300)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    112446776 (EP300)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    112446776 (EP300)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    112446776 (EP300)
   04935 Growth hormone synthesis, secretion and action
    112446776 (EP300)
   04919 Thyroid hormone signaling pathway
    112446776 (EP300)
   04916 Melanogenesis
    112446776 (EP300)
  09156 Nervous system
   04720 Long-term potentiation
    112446776 (EP300)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112446776 (EP300)
   05206 MicroRNAs in cancer
    112446776 (EP300)
   05203 Viral carcinogenesis
    112446776 (EP300)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    112446776 (EP300)
   05215 Prostate cancer
    112446776 (EP300)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112446776 (EP300)
   05161 Hepatitis B
    112446776 (EP300)
   05164 Influenza A
    112446776 (EP300)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112446776 (EP300)
   05165 Human papillomavirus infection
    112446776 (EP300)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    112446776 (EP300)
  09164 Neurodegenerative disease
   05016 Huntington disease
    112446776 (EP300)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bta03000]
    112446776 (EP300)
   03036 Chromosome and associated proteins [BR:bta03036]
    112446776 (EP300)
   03029 Mitochondrial biogenesis [BR:bta03029]
    112446776 (EP300)
Enzymes [BR:bta01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     112446776 (EP300)
Transcription factors [BR:bta03000]
 Eukaryotic type
  Other transcription factors
   Pocket domain CBP
    112446776 (EP300)
Chromosome and associated proteins [BR:bta03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    112446776 (EP300)
Mitochondrial biogenesis [BR:bta03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Coactivators
    112446776 (EP300)
SSDB
Motif
Pfam: KAT3 KIX Creb_binding zf-TAZ RING_CBP-p300 PHD_P300 Bromodomain ZZ KIX_2 Npa1 Med15_N
Other DBs
NCBI-GeneID: 112446776
NCBI-ProteinID: XP_024848564
Ensembl: ENSBTAG00000016198
VGNC: 57349
Position
5
AA seq 2411 aa
MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD
ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQGMASQAQQNSPGLGLINS
MVKSPMAQAGLTSPNMGMGTSGPNQGPTPSATGVMSSPVSQPAMGMNTGMNAGMSPGMLT
AGNGQGMMPNQVMNGSIGAGRGRPNMQYPNPGMGSAGNLMTEPLQQGSPQMGGQTGLRGP
QPLKMGMMNNPNPYGSPYTQNSGQQMGASGLGLQIPTKSVLPNSLSPFAMDKKAVPGGGM
PNMGQQQAPQVQQPGMVAPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
AGDKRNQQSILTGAPVGLGSTSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ
MPTQPQVQAKNQQNQQSGQSPQGMRPMSNMSASPMGVNGGVGVQPSNLLSDSMLHSAINS
QNPMMSDNGSVASLGPMPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
SAASMVPVMNTGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRVTPQPGLNQFGQMSM
PQPPIGPRQNSPLQHHVQLAQTGTLNPPMGYGPRMQQPSSQSQFLPQTQFSTQGMNVTNM
PLAPSGGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPPLPQPALHQNSPSPVPSRTP
TPHHTPPSIGAQQPPATAIPAPVPTPPAMPPGPQSQVLHPPPRQTPTPPPTQLPPQVQPS
LPAAPSVDQAQQQPLSQQSTAASVPTPTAPLLPPQPATPLSQPAVSLEGQVSNPPSTSST
EVNSQAIPEKQPSQEARMEPKMEVEAPEPAETQPEDVPETKAEDCKVEPTETEERGTELK
TETKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMSTLEALYRQDPESLPFRQPVD
PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYK
YCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHF
CEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL
HHEIIWPSGFVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNEFLRRQNHPESGE
VTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQE
YGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP
SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKE
LPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK
SSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP
CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR
WHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQ
SLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENK
CPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG
QQPTTPQTPQPPPPSQPQPTPPNNMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPL
PGPPPAAVEVAMQIQRAAETQRQMAHVQIFQRPIQHQMPQMTPMAPMGMNPPPMARGPGG
HLEPGMGPTGMQQQPPWAQGGLPQPQQLQSGMPRPAMMSVSQHGQPLNMPPQPGLGQVGV
SPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQ
PLPGQPGLQPPAMPGQQGVHSSPAMQNLNPMQAGVPRAGLPQQPTQQQQLPPPMGGMSPQ
AQQMNMNHSTMPSQFRDILRRQQMMQQQQQGAGPGMGPGLANHNQFQPPQGVGYPAPQQQ
PPPRMQHHMQQIPQGSMGQMGQLPQALGAEAGASLQAYQQRLLQQQMGSPAQPNPMSPQQ
HMLPSQAQSPHLQGQQIPSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ
TSSPHPGLVAAQGNPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLGTDNSDLN
SNLSQSTLDIH
NT seq 7236 nt   +upstreamnt  +downstreamnt
atggccgagaatgtcgtggaaccggggccgccttcagccaagcggcctaaactctcatct
ccggccctctcggcgtccgccagcgatggcacagattttggctctctgtttgacttggag
cacgacttaccagatgaattaatcaactctacagaattgggactaaccaatggtggtgat
attagtcagcttcagacaagtcttggcatagtacaagatgcagcctctaaacataaacag
ctgtcagaattgctacggtctggtagttcccctaacctcaatatgggggttggtggccca
ggccaaggcatggccagccaagcccaacagaacagtcctggattaggtttgataaatagc
atggtcaaaagcccaatggcccaggcaggcttgacttctcccaacatggggatgggcact
agtgggccaaatcagggccccacgccgtctgcaacaggtgtgatgagcagtcccgtcagt
cagcctgccatgggaatgaacacggggatgaacgctggcatgagtcccggcatgctgact
gccggcaatggacaagggatgatgcctaatcaagtcatgaacggttcaattggagcaggc
cgggggcgaccgaatatgcagtacccgaacccaggcatgggaagtgctggcaacttaatg
actgagccgctgcagcaaggctctccccagatggggggacagacgggactgagaggcccc
cagcctctcaagatgggaatgatgaacaaccctaatccttacggttcaccatacactcag
aattctggacagcagatgggagccagtggccttggtctccagattccgacaaagtctgta
ctaccaaatagcttatctccatttgcaatggacaaaaaggctgttcctggtggaggaatg
cccaatatgggccagcagcaggccccacaggtccagcagccaggcatggtggctccggtg
gcccaggggatgggttctggggcacatacagctgatccggagaagcgcaagctcatccag
cagcagcttgtcctcctcctgcacgctcacaagtgccagcgccgggagcaggccaacggg
gaggtgaggcagtgcaaccttccccactgtcgaaccatgaagaacgtcctaaaccacatg
acacactgccagtcgggcaagtcctgccaagtggcacactgtgcatcttctcgacaaatc
atttcccactggaagaattgtacaaggcatgattgtcctgtgtgtctccccctgaaaaac
gctggagataagagaaatcaacagtcaattttgactggagcaccagttggacttggcagt
actagctctctaggggtgggtcaacagtccactcccagcctaagcactgtcagtcagatt
gatcccagctctatagaaagagcctatgcagcccttggactgccctatcaagtaaatcag
atgccgacccagccccaggtgcaagcgaagaatcagcagaaccagcagtctgggcagtct
ccccaagggatgcggcccatgagcaacatgagtgctagtcctatgggagtaaatggaggt
gtaggggttcaaccgtcgaatcttctttctgactcgatgttgcattcagccataaattct
caaaacccaatgatgagtgacaatggcagtgtggcctctctgggtcctatgccaacagca
gctcaaccatccagtactggaattcggaagcaatggcatgaagatattactcaggatctt
cgaaatcatcttgtccacaaactcgttcaagccatatttcccactccggatcctgctgct
ttaaaagacagacggatggaaaacctagttgcatatgcccggaaagtggaaggggacatg
tatgaatcggcaaacaatcgagcggaatactaccacctgctagctgagaagatctataag
attcagaaggaactagaagaaaagcgaaggactagactacagaaacagaacatgctacca
agtgctgcaagcatggtgccagttatgaacacagggcctaacatggggcagccacaacca
ggaatgacttctaatggccctctccctgatccatctatgatccgcggcagtgtgccaaac
cagatgatgcctcgggtaactccacagcctggtttgaatcagtttggccagatgagtatg
cctcagccccctattggaccccggcaaaactctcctcttcagcaccatgtacagttagct
caaactggaacacttaacccgcctatgggctacgggcctcgcatgcagcagccttccagc
cagagccagtttcttcctcagactcaattctcaacacagggaatgaatgtaacaaatatg
cctttggctccgtctggcggtcaagcaccagtgtctcaagcacagatgtccagttcttcc
tgtcctgtgaactctcctataatgcctcctgggtctcaagggagccacattcactgtccc
cctctccctcaaccagctctgcatcagaactcaccctcacccgtacctagtcgcaccccc
acccctcaccacactccccctagcataggggctcagcagccaccagcaacagcaatccca
gcccctgttcctacgcctccagccatgccacctggcccacagtcccaggttctccatccg
cctccaagacagacgcctacgccgccaccaacacaacttcctccccaagtgcagccttcg
cttcctgctgctccctcagtcgaccaggcgcagcagcagcctctgtcccagcaaagcaca
gcagcctctgtgcccaccccgacggcacccctgctgcctccgcagccggcaactccactt
tcccagccagctgtaagcctcgaagggcaggtatcaaaccctccatccactagtagcacg
gaagtgaattctcaggccattcctgagaagcagccttcacaggaagcaagaatggagcct
aaaatggaagtggaggcgccagaaccagcagagactcagccggaggatgttccagagact
aaagcagaagactgtaaagtagaacctacagaaaccgaagagagaggcactgaattaaaa
actgagacaaaagaggaagaagaccagccaagtacttcagcgacccagtcatctccagcc
ccaggacagtcaaagaagaagattttcaaacctgaagagttacgacaggcactgatgtca
acactggaggcactttaccgacaggatccggaatcccttcccttccgtcagcctgtggac
cctcagcttctaggaatccctgattactttgatattgtgaagagccctatggatctttct
accatcaagaggaagttagacactggacagtatcaggagccctggcagtatgtggatgac
atttggctcatgttcaacaatgcttggttatataatcggaaaacatcacgggtgtacaaa
tactgctccaagctgtctgaggtcttcgaacaagaaattgaccctgtcatgcaaagcctt
ggatactgttgtggcagaaagttggagttctctccacagacactctgttgctatggcaaa
cagttatgcacaatccctcgtgatgccacttactacagttatcagaacaggtatcatttc
tgtgagaagtgtttcaatgaaatccaaggggagagcgtttctttgggggatgacccttcc
caacctcaaactacaataaataaagaacaattttcaaagagaaaaaatgacactctggat
cctgaactgtttgttgagtgtacagagtgtgggagaaagatgcatcagatctgtgtcctc
catcacgagatcatctggccatcgggatttgtctgtgatggttgtttaaagaagactgca
cgaactagaaaagaaaataagttttctgctaaaagactgccatctaccaggcttgggaca
tttctggagaatcgtgtgaatgagtttctgaggcgacaaaatcaccctgagtcaggagag
gtcactgttcgagtagttcatgcttctgacaaaactgtggaagtcaaaccaggcatgaaa
gcaagatttgtagatagtggagagatggcagaatcctttccatatcgaaccaaagcgctc
tttgccttcgaagagatcgatggtgttgacttgtgcttctttggtatgcacgttcaagag
tatggctctgactgccctccgcccaaccagaggagagtatacatatcatacctcgatagt
gttcacttcttccgtcctaaatgcttgaggactgccgtctatcatgaaatcctaattgga
tatttggaatatgtcaagaaattaggatacacaacagggcatatttgggcgtgtccgcca
agtgaaggagacgactacatcttccattgccacccccctgaccagaagatacccaagccc
aagcgactgcaggagtggtacaaaaagatgctcgacaaagctgtgtccgagcgaatcgtc
catgattataaggacattttaaaacaagctactgaagatcgattgacaagcgcgaaggaa
ttgccttactttgagggtgatttctggcccaacgtcctggaagagagcattaaggaactg
gaacaggaggaggaggagcggaagcgggaggagaacaccagcaacgagagcacagatgtg
acaaagggagacagcaaaaatgctaaaaagaaaaacaacaagaaaactagcaaaaacaag
agcagcctgagtcgtggcaataagaagaagccaggcatgcctaacgtatccaacgacctc
tcacagaaattgtatgccaccatggagaagcacaaagaggtcttctttgtgatccgtctc
atcgctggccctgccgccaactccctgcctcccatagttgaccccgaccccctcatcccc
tgtgacctgatggatgggcgggatgcctttctcacccttgcaagggacaagcacctggag
ttctcgtcgttgcgaagagcccagtggtccaccatgtgcatgctggtggagctgcacacc
cagagccaggaccgctttgtctacacctgcaacgagtgcaagcaccacgtggagacacgc
tggcactgcaccgtgtgtgaggattatgacttgtgtatcacctgctacaacactaaaaac
cacgaccacaagatggagaagctcgggctggggcttgatgacgagagcaacaaccagcag
gctgccgccacgcagagcccgggagactcccgccgcctgagcatccagcgctgcatccag
tcgctggtgcacgcctgccagtgccgcaacgccaactgctcgctgccgtcctgccagaag
atgaagcgggtggtgcagcacaccaagggctgcaagcgcaagaccaacggcggctgcccc
atctgcaaacagctcatcgccctgtgctgctaccatgccaagcactgccaggagaacaag
tgccccgtgcccttctgcctcaacatcaagcagaagctccggcagcagcagctgcagcac
cggctccagcaggcccagatgctgcgcaggaggatggccagcatgcagcggactggtgtg
gtggggcagcagcagggcctgccctcccctacccctgccacccccaccacgccgacgggc
cagcagcccaccaccccgcagacaccccagcccccacccccctctcagccccagcccaca
cctcccaacaacatgccgccctacttgcccaggactcaagctgctggcccagtgtcccag
ggcaaggcagcaggccaggtgacgcccccgacccctcctcagactgctcagcccccactt
ccgggacccccacctgcagcagtggaggtggccatgcagattcagagggcagccgagacg
caacgccagatggcccacgtgcaaatctttcagcggccgatccagcaccagatgccgcag
atgactcccatggcccctatgggtatgaacccgccccccatggccagagggcctggtggg
catttggagccagggatggggcccactggcatgcagcagcaacccccatgggcccaggga
ggactgccccagccccagcagctgcagtccgggatgccccggccagccatgatgtcggtg
tcacagcacgggcagcccctgaacatgcctccccagccgggcctgggccaggtaggtgtg
agccctctcaagccaggcactgtgtctcaacaagccttacagaacctcctgcggactctc
aggtctcccagctcccccctgcagcagcaacaggtgctcagtatccttcatgccaacccc
cagctattggctgcgttcatcaaacagcgggctgccaagtacgccaactccaacccgcag
cccctccccgggcagccgggcctgcagccccccgctatgccaggtcagcagggggtccac
tccagccccgccatgcagaacttgaaccccatgcaggcaggtgtcccgagggctggcctg
ccccagcagcccacgcagcagcagcagctcccgccacccatgggcgggatgagcccacag
gctcagcagatgaacatgaatcacagcaccatgccctcgcaattccgagacatcttgagg
cgacagcagatgatgcagcagcagcagcagggagcggggccagggatgggcccggggctg
gccaaccacaaccagttccagcctccccagggcgtgggctaccctgccccgcagcagcag
ccgccaccgcgaatgcagcatcacatgcagcagataccacaagggagcatgggacagatg
ggccagctcccgcaggccctgggagcagaggcgggagccagtctgcaggcctaccagcag
cggctccttcagcaacagatgggctcgccggcccagcccaaccccatgagcccccagcag
cacatgctcccgagtcaggctcagtccccgcacctccaaggccagcagatcccgtctctc
tccaatcaagtgcgatctccccagcctgtcccttctccgcggcctcagtcccagcccccc
cactccagcccttccccacggatgcagcctcagccttctccacaccacgtctccccacag
accagttctccacatcctggactggtcgctgcccagggcaaccccatggaacaagggcat
tttgccagcccggaccagaattcgatgctctctcagctcgctagcaatccaggcatggca
aacctccatggtgcaagcgccacggacctgggactcggcaccgacaactcagacttgaat
tcaaacctctcacagagtacactagacatacactag

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (18)   

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